23/05/2025
Intriguing research from the Garvan and UNSW has found abnormal/mutated immune cells may be why some people with coeliac disease continue to have bad symptoms and damaged villi, despite strictly avoiding gluten.
👉️ They found that 7 out of 10 people with refractory coeliac disease had a high amount of immune cells with genetic mutations, appearing to give the cells a growth and survival advantage….. which may be why they were still found even when gluten was removed from the diet.
🟢 They are still determining if these cells are the cause or the results of the chronic inflammation that persists in this group.
🟢 If they can confirm that these mutated cells are in fact responsible for the disease not healing......
🟢 This should make it possible to target those cells with existing drugs.
🟢 Taking these cells away should lead to healing.
https://www.unsw.edu.au/newsroom/news/2025/05/rogue-immune-cells-explain-why-a-gluten-free-diet-fails-for-some-people-with-coeliac-disease