16/12/2025
✨These guideline updates are a major step forward for adults under 45 with suspected coeliac disease!
Extra notes from the ESsCD guidelines:
🌾 HLA-DQ2/DQ8 testing isn’t needed for initial diagnosis, but may help if results are unclear, for someone already gluten-free, or for high-risk family members. A negative result rules out coeliac disease.
🌾 Already gluten-free? A gluten challenge (≥3g/day* for 6 weeks, ~1–2 slices bread) may be needed, followed by blood tests ± biopsy. Low-FODMAP gluten foods can help with symptoms.
🌾Saliva or stool tests are not accurate. Feeling better off gluten alone cannot confirm coeliac disease.
These updates mean more accurate diagnoses, fewer unnecessary biopsies, and clearer guidance for adults at risk — especially if coeliac disease runs in your family.
✨ Follow along for more research updates in the coeliac space!
*Note this differs from the Coeliac Australia gluten challenge recommendations of 10g of gluten per day for 6 weeks. Speak with your medical team about the best way forward for you if you are required to do a gluten challenge.