15/06/2024
It’s been a week since this ground-breaking dementia and lifestyle medicine study was published, and we have not seen it reported in any Australian mainstream or medical media. If it had been a drug study with similar positive results, it would have been all over the media. We can only speculate on why this study has been ignored – was it the plant-based diet or the paradigm-breaking idea that lifestyle could be more effective than pharmaceuticals?
Here is what we posted about the study on our nutrition page last weekend:
Intensive lifestyle changes can improve cognition and slow the progression of early Alzheimer's disease, finds this landmark study directed by Dr Dean Ornish. This is the first randomised, controlled clinical trial to investigate the effects of lifestyle change on those already diagnosed with Alzheimer’s disease. Participants and their spouses/carers were provided with whole foods, plant-based meals and snacks, dietary supplements, and an in-person and online intensive program of exercise, stress management and group support. Compared to the control group, the study found a statistically significant improvement in 3 out of 4 measures of cognitive function and a borderline significant improvement in the fourth. Finding a statistically significant improvement in a small study (49 subjects) over a relatively short period of time (20 weeks) suggests that the lifestyle intervention had a powerful effect. There were also changes in biomarkers for Alzheimer's disease and metabolic health: LDL cholesterol was reduced by 31%. A dose effect was observed – higher adherence to the lifestyle intervention was associated with greater improvement in cognition and biomarkers.
Lifestyle intervention studies can raise more questions. Why did some subjects in the intervention group not do well? Was it related to adherence or other factors related to the disease? What was the relative importance of healthy plant-based nutrition versus supplements, exercise, meditation, and group support?
We call on research institutions to fund larger studies to validate the findings of this research and answer some of the questions it raises. However, given the established evidence linking lifestyle factors with the development of Alzheimer's disease and the therapeutic benefits of lifestyle found in this study, we shouldn’t have to wait for further research to recommend nutrition and lifestyle interventions as standard treatment for all patients with a diagnosis of early Alzheimer's disease.
Link to paper - https://alzres.biomedcentral.com/articles/10.1186/s13195-024-01482-z
Link to Dr Michael Greger’s summary of the new study - Can Alzheimer's Disease Be Reversed with a Plant Based Diet? https://nutritionfacts.org/video/can-alzheimers-disease-be-reversed-with-a-plant-based-diet/
If you are looking to make significant lifestyle changes to prevent or treat early-stage Alzheimer's disease, please join us at our next seven-day immersion retreat in the Yarra Valley, Victoria. Dates: 8th to 15th September. Details - https://www.wholefoodsplantbasedhealth.com.au/immersion/