09/10/2025
Low testosterone can have a profound impact on mood and emotional wellbeing. Testosterone plays an important role not only in physical health like muscle mass, energy, and libido but also in brain chemistry and emotional regulation. When levels drop below the optimal range, men often report feeling unusually flat, unmotivated, or even depressed.
This is because testosterone influences key neurotransmitters such as serotonin and dopamine, the same chemicals that help regulate mood, pleasure, and motivation. Low testosterone can lead to symptoms that closely resemble clinical depression such as persistent sadness, loss of interest in activities, low self-esteem, irritability, and difficulty concentrating.
Feeling depressed, fatigued or low s*x drive? You could have low testosterone. Read about the link between testosterone and depression.