04/04/2025
Sleep is so essential, yet we often discount it. It’s almost a badge of honour to brag about how you can survive on Little sleep. But it’s not healthy, for just about anybody. Thanks Tracey Yeend - Hormonal, Nutritional & Environmental Health for the share. 
A recent study highlights the significant impact even a single night of sleep deprivation can have on the immune system.
Researchers found that losing just one night's sleep can alter circulating immune cells, particularly monocytes, and promote systemic inflammation, potentially increasing the risk of obesity, diabetes, and heart disease.
The study involved 237 healthy adults and revealed that obese individuals already experienced poorer sleep quality, elevated low-grade inflammation, and increased non-classical monocytes. Strikingly, one night of sleep deprivation in lean volunteers transformed their monocyte profiles to resemble those of obese individuals, a state associated with chronic inflammation.
The lead researcher, Fatema Al-Rashed, emphasizes that modern society's technological advancements and evolving expectations are disrupting sleep patterns and impacting immune health. The researchers advocate for further research into the relationship between sleep deprivation and immune responses and suggest potential interventions like sleep therapies and technology usage guidelines to alleviate these effects.
RESEARCH PAPER 📄
Fatema Al-Rashed et al., "Impact of sleep deprivation on monocyte subclasses and function", The Journal of Immunology (2025)