11/10/2025
Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi are awarded the Nobel Prize in Physiology or Medicine 2025 for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body. The body’s powerful immune system must be regulated, or it may attack our own organs. They discovered how the immune system is kept in check
Mary E. Brunkow
Institute for Systems Biology,
Seattle, USA
Fred Ramsdell
Sonoma Biotherapeutics,
San Francisco, USA
Shimon Sakaguchi
Osaka University,
Osaka, Japan
Nobel Prize
