Keto Kitchen

06/05/2025

Interesting ready for expecting moms 🌸

A recent study in Nature Metabolism highlights how maternal exercise during pregnancy can improve offspring metabolic health through a mechanism involving the adipokine SERPINA3C. These findings provide valuable insights into how early-life metabolic programming occurs and may offer new approaches for preventing obesity and metabolic disorders.

The research shows that maternal physical activity increases SERPINA3C production in white adipose tissue (WAT), which is then transferred into fetal circulation. Once in the fetus, this protein influences fat cell development by enhancing expression of Kruppel-like factor 4 (KLF4), a transcription factor that regulates inflammation and metabolic balance. By increasing KLF4 levels, maternal exercise protects offspring from diet-induced obesity, insulin resistance, and chronic inflammation, even when they are later exposed to a high-fat diet (HFD).

To confirm the role of SERPINA3C, researchers conducted both knockdown and overexpression experiments. When maternal SERPINA3C was reduced, offspring exhibited higher fat accumulation, increased adipose inflammation, and impaired glucose metabolism. Conversely, artificially increasing SERPINA3C levels in maternal WAT replicated the metabolic benefits of maternal exercise in offspring, even in the absence of physical activity.

SERPINA3C activates the cathepsin G-integrin β1-PI3K pathway, which triggers epigenetic modifications in fetal fat cells. It promotes the removal of methyl groups from the Klf4 gene, sustaining its expression and preventing adipose inflammation.

These findings highlight the influence of maternal health on offspring well-being. Engaging in regular physical activity during pregnancy not only benefits the mother but can also provide lasting metabolic advantages for her child. Understanding these mechanisms could also inform early-life interventions aimed at reducing the risk of obesity, diabetes, and other metabolic diseases. As research continues to uncover the biological pathways connecting maternal lifestyle to offspring health, there is more potential for strategies that center upon metabolic health.

Read the study here: https://www.nature.com/articles/s42255-024-01213-6

06/05/2025

How fun does this sound? 😊😀

🍬 Save the Date: The Great Candy Run 5K is back on Sunday, Nov. 9, 2025! 🍭

The sweetest race of the year supports families facing fetal health diagnoses — and every step makes a difference. 💙

🏃‍♀️ Join us in Colorado or virtually
💝 Not running? Donate and still make an impact

Every step — and every dollar — brings us closer to stronger beginnings and brighter futures for families everywhere.

06/05/2025

Need to register

Join us to learn more about epilepsy in the workplace, your rights and reasonable accommodation by employers for employees with epilepsy. Our dynamic panel will unpack these issues with their experience, expertise and insight for a truly educational webinar not to be missed by workers and employers....

03/18/2025

Another epilepsy study is looking for participants aged 12 and up. Participants who suffer prolonged seizures are the ideal candidates.

Clinical Trial Opportunity:
UCB Biopharma is conducting a phase 3 clinical trial called STARS that is investigating a drug for prolonged (seizures typically lasting more than 3 minutes with a predictable pattern). The study is looking for patients 12 years of age and older who have focal or generalized epilepsy, or a combination of the two. It is required for the patient to have an active caregiver to be part of this study.

For more study information, please contact an experienced Patient Navigator at +1 470-523-2502. The Patient Navigators are healthcare professionals available to help you better understand this clinical study and decide if it may be right for you.

To learn more about the study visit https://www.starsepilepsystudy.com/

03/18/2025

Congrats on getting to a seizure free point!! 🙌😊

A parent's peace of mind when it comes to their child's safety is priceless. We are grateful to all the DDF supporters whose generosity makes it possible to provide detection monitors to families in need. Please read the feedback from one family below:

"I cannot put into words the peace of mind that Danny Did Foundation provided our family. Before we were able to purchase our device, I would stay awake as long as I could at night, terrified our daughter may have a seizure during her sleep and stop breathing. I was crippled by fear that she would experience SUDEP due to the type of seizure she has experienced. This has given her independence back as a young adult who has been able to start her first semester of college, as well as her first job! She has been seizure-free since June, but the lingering fears of a mother have only been calmed due to this potentially life-saving device. Thank you for the incredible gift of funding for devices that we could not have been able to provide on our own."

03/18/2025

We are proudly Canadian at Keto Kitchen but we also love and support our American neighbors who are suffering at the hands of their delusional President.

True North Strong & Free! 🇨🇦 Celebrating the people, places, and spirit that make Canada great!

We share positivity, unity, and pride—always with kindness. No negativity, no profanity—just pure Canadian love. 🍁

🇨🇦🇨🇦JOIN US!! Help spread Canadian pride! 🇨🇦🇨🇦

03/18/2025

Did you know Greece has prioritized wheelchair access at their beaches?



https://accessnow.com/blog/greece-makes-hundreds-of-beaches-wheelchair-accessible/

03/16/2025

Are there any Canadians in this group?

03/02/2025

🇨🇦🇨🇦🇨🇦

🇨🇦 🧐Think our buying boycott isn’t big enough?

Think again.

📌 This data represented only a handful of border crossings for ONE MONTH and equates to a potential 🇺🇸 $81 million US lost from just TWO USA border crossings in B.C.!

🇨🇦Pour yourself a tea or drink, this is a long but worthwhile read if you are following the Trump fiasco and buying bans!

✅Cross-border shopping and traffic from British Columbia, including areas like Langley and White Rock, into the United States has experienced a significant decline over the past month. 🙌

This decrease is attributed to recent political tensions, and Trump’s threats of annexing Canada.

🇨🇦 According to data from Cascade Gateway, the Peace Arch border crossing, which is one of the primary crossings near White Rock, saw a notable reduction in traffic. In February 2025, the average daily number of cars heading south through this crossing was approximately 3,500, compared to nearly 5,000 daily in February 2024, indicating a decrease of about 30%.  

🇨🇦Additionally, during the Family Day/Presidents’ Day long weekend, car traffic at the Peace Arch crossing decreased by over 40% compared to the same period in the previous year. Other crossings in southwest B.C. experienced declines exceeding 20%. 

🇨🇦This downward trend is further supported by observations from local businesses. For instance, the manager of Peace Arch City Cafe & Bar in Blaine, Washington, reported a nearly 30% drop in customers over the past couple of months, attributing this decline to the heightened political tensions. 

🇨🇦What does that mean in $$$?

I looked at data for ONLY 2 border crossings below:

🚙 Peace Arch crossing saw a 30% decrease in daily crossings.

🚗 The long weekend (Family Day/Presidents’ Day) saw a 40% decline

(Other border crossings in southwest BC saw 20%+ declines.)

💰Average Spending Per Visitor:
• A 2018 study by the Pacific Northwest Economic Region (PNWER) estimated that Canadian cross-border shoppers spend an average of $100–$200 USD per trip, mainly on:
• Groceries
• Gasoline
• Clothing
• Other retail goods

💰For a more recent and localized estimate:
• A Canadian shopper in Washington State (2024 reports) spent around $150 per trip on average.

📉 Estimating Lost Sales:

Pre-Decline Traffic (February 2024)
• 5,000 daily crossings at Peace Arch.
• Estimated $150 per trip per Canadian shopper.
• Potential daily sales = 5,000 × $150 = $750,000 USD
• Monthly (30-day) estimate = $22.5M USD

📊Post-Decline Traffic (February 2025)
• 30% drop → 3,500 daily crossings.
• New potential daily sales = 3,500 × $150 = $525,000 USD
• New monthly estimate = $15.75M USD

Total Estimated Sales Loss:
• Daily loss: $750,000 - $525,000 = $225,000 USD per day
• Monthly loss: $22.5M - $15.75M = $6.75M USD per month
• Annualized loss (if trend continues)….. insert drum roll please….🥁

✅$81M USD per year!

This decline directly affects businesses in Blaine, Bellingham, and other Washington State border towns that depend on Canadian shoppers for retail, fuel, and tourism revenue.

🧐Think our boycott isn’t big enough? Think again. This data represented only a handful of border crossings for ONE MONTH.

Think bigger, Amazon, online sales, grocery store spending. All of it matters.

THIS IS WHERE WE WIN.

🇨🇦Go Canada!🇨🇦



*Ai generated photo/data research

02/24/2022

Does anybody need a seizure watch? We have a first-generation one that I am happy to draw a name for and gift it.... Samsung phone included in the gifting.

Comment here below to enter, and share the post about the "Mee See Tees" funky t-shirts to qualify as an entry.

Will draw a winner in the next 2 weeks :)

02/22/2022

😍😍PROMO CODE: BUY2 for free shipping when you buy any two!😍😍

The CUTEST t-shirts for your little ones! Flippin' fun graphics that your kids see,, not you! PLUS a portion of the proceeds goes to protect, clean, and save our oceans in the Pacific Northwest!

https://www.meeseetees.com/

09/17/2021

Can somebody please explain to me how the science is going to work for long-term studies of Covid vaccines with a proper, scientifically coordinated placebo/control group, if everybody on the planet gets vaccinated?