Saguaro Biosciences, Quebec, QC (2026)

02/03/2026

🌵✨ One week to go: Saguaro Bio at ! ✨🌵

We are counting down the days until we head to (Society for Laboratory Automation and Screening) 2026 conference at Boston. This year, we are showcasing the latest applications of our non-toxic, live-cell dyes with a full lineup of posters and podium presentations.

Add these to your SLAS agenda:

🎤 Podium Presentation : A Screening Workflow for Live Cell Painting: Profiling Drugs at Scale to Generate New Insights Presented by:

Poster #1335-A: Implementation of a Live Cell Profiling Screen: Improving Bioactivity Classification and Detection over Fixed Cell Painting
Poster #1389-E: Regulatory Adoption of Organoids and 3D Models: Tailor-Made Tools that Deliver Comprehensive Insights
Poster #1218-D: Beyond the ATP Readout: A Novel Imaging Assay to Reveal Distinct Mechanisms of Cytotoxicity in High-Throughput

Stop by Booth #741 to discuss how Saguaro dyes can benefit your screening pipelines, or book a meeting in advance: info@saguarobio.com

See you in Boston! 👋

01/29/2026

🌵✨SLAS2026 Podium Presentation: Revealing Bioactive Responses, Missed by Fixed Cell Painting, with ChromaLIVE ✨🌵

We are excited to announce the podium presentation of titled "A Screening Workflow for Live Cell Painting: Profiling Drugs at Scale to Generate New insights."

⏰ When: Monday, February 9, 2026, 11:00 AM – 11:25 AM EST
📍 Where: Room 210A
🎤 Presentation track: Advanced Imaging and High Content Assays

Join us to learn more about the new automated workflow designed for discovery-scale screening and
👉 Methods for profiling cells without perturbing them, using Saguaro’s non-toxic live-cell painting dyes.
👉 How to integrate modular automation for robust, high-throughput live-cell painting.

👉 How ChromaLIVE outperforms fixed and end point cell painting assays by delivering better bioactivity detection and phenotypic distinctiveness.

01/27/2026

🌵✨Saguaro is heading to Boston for !✨ 🌵

Join us at the (Society for Laboratory Automation and Screening) conference between February 9-11.

🌟We might be unveiling a brand-new dye with our signature non-toxic, mix-and-read simplicity, and data-rich performance!!

📩 Want to connect at the event? Stop by Booth #741 to discuss how Saguaro dyes can benefit your screening pipelines in 2D and 3D, or book a meeting in advance: 📧 info@saguarobio.com

01/20/2026

Check out this new paper by the Chan-Zuckerberg making use of ChromaLIVE to develop this new AI framework for scalable biological microscopy. 👀🚀

A better understanding of biological phenomena involves combining datasets from different imaging techniques and different model scales (organelles, cells, organisms). 🧬🔬 Their new framework, WaveOrder, leverages differentiable wave-optics to solve optical inconsistency, a bottleneck in analyzing these different datasets at scale. 📈

Validating their model involved using an optical pooled screen of A549 cells and ChromaLIVE non-toxic dye, the leading technology for providing high-quality image-based profiling data to feed AI models with! 🤖✨

Check it out: https://zurl.co/ICObL

Liu Mehta

01/13/2026

🌵 Tracking real-time ER stress dynamics in iPSC-derived neurons 🌵

Using ER-LIVE, our non-toxic live-cell Endoplasmic Reticulum stain, we successfully tracked drug-induced ER stress in real-time capturing time-sensitive phenotypic changes that static endpoint imaging misses.

The non-toxic nature and simple mix-and-read protocol makes ER-LIVE perfect for long-term imaging of sensitive models like iPSC-derived neurons, allowing you to observe:

❇️ ER Clumping ❇️ Membrane Reorganization ❇️ Blebbing ❇️ Perinuclear ER aggregation ❇️ Cell shrinkage and ❇️ Breakdown of extended ER tubules

📧 Reach out to us at info@saguarobio.com 🔗 Check out our website to learn more: https://zurl.co/judUk

12/22/2025

Christmas Party at Saguaro 🎄🪓

Last week, our team enjoyed a fantastic Christmas party filled with fun activities and great moments together.

We kicked things off with an axe-throwing tournament; a perfect way to break the ice and get everyone laughing… or screaming! 🪓😄

Next up was the escape room. Locked inside an abandoned hospital, we worked together, followed the clues, and managed to escape just in time 🚪✨. A great reminder that we truly are a strong team when it comes to solving problems together.

To wrap up the evening, we headed to Quai 1635 to enjoy a wonderful meal together 🍷🍝.

Thank you to the entire Saguaro team for the energy, collaboration and positivity you bring every day. You truly make it a pleasure to work together and to share such a great year.

Wishing you all a very Merry Christmas! 🎄✨

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12/11/2025

🌵 ✨Implementing live cell painting in HTS: A How-To Guide ✨🌵

We are excited to share with you our latest How-To Guide. Our goal with this guide is to provide a reference for drug discovery groups to implement this powerful new approach into their own HTS pipelines. 🚀

Inside the guide:
🔶 How to design a scalable workflow that preserves cell health.
🔶 Strategies for capturing robust profiling data in live cells without perturbations.
🔶 A practical reference for integrating this approach into existing HTS pipelines.

If you are a drug discovery group looking to adopt this emerging approach, this is your blueprint.

Refer to the guide here: https://zurl.co/hMeij

Reach out to us at info@saguarobio.com or visit our website for more information: https://zurl.co/5YIYW

12/09/2025

🎄✨Saguaro Holiday discounts: Better Data. Bigger Savings✨🎄

🎅Saguaro Santa is feeling extra festive this holiday season!! You can now stock up on our industry-leading, non-toxic, live-cell dyes with a special year-end Discount!

🔶 From today until the 31st of December enjoy

🧪 10% off when you buy 3 tubes
🧪 15% off when you buy 6 tubes
🧪 20% off when you buy 12 tubes

Upgrade your imaging with dyes that treat your cells gently, allowing for longer, more biologically accurate and unperturbed cellular responses.

👉 Reach out to us at info@saguarobio.com or visit our website to learn more: https://zurl.co/M6lRA

12/02/2025

🌵✨ New publication alert: ChromaLIVE™ predicts drug response for clinical applications ✨🌵

We are incredibly proud to announce the peer-reviewed publication in iScience titled "High-content imaging of primary chronic lymphocytic leukemia cells predicts patient cohorts with distinct cellular drug responses "

The study utilized ChromaLIVE™ to perform high-content live-cell painting on primary Chronic Lymphocytic Leukemia (CLL) patient samples to do what standard clinical markers couldn't:

👉 stratify Leukemia patients into distinct cohorts based on cell phenotypes
👉 predict therapeutic drug responses by distinguishing between cell states like stress, quiescence, and apoptosis.

See how the patient drug response was predicted just by watching the cells live: https://zurl.co/x8GVO

👏 A huge congratulations to Andrews and his entire team at Sunnybrook Research Institute for leading this fantastic study!

11/18/2025

🌵✨ Great news! Our Drug Profiling Service Webpage is finally online!✨🌵

Take a look! 👇

Learn more about how we’ve already helped multiple pharma customers in the last year get new drug insights they didn’t expect 🚀

https://zurl.co/miwPH

In a nutshell:

👉 Powered by ChromaLIVE™ dye, the leading technology for profiling drugs with images, outperforming fixed-cell and label-free approaches.

👉 Capture the most accurate biology: unperturbed cells with the truly non-toxic ChromaLIVE™. Obviate wash and fixation.

👉 More data points with kinetics: more data and more context for better drug insights

👉 Leverage our rich and unique library of 1000’s of drug annotations

🌵Let our experts handle the wet lab, imaging, and analytics so you can focus on discovery 🌵

11/13/2025

Saguaro is on the move again: next stop, London! 🇬🇧✨🌵

📍 Join us at: – High Content Imaging & Flow Cytometry in Drug Discovery 2025
🏢 Venue: GSK Medicines Research Centre, Stevenage, UK
🗓️ Dates: 19–20 November 2025

Our Co-Founder and CCO, , will be on-site meeting with clients and partners showcasing how Saguaro dyes are advancing non-toxic, data-rich live-cell imaging for more insightful drug discovery.

Don’t miss our poster ( #25): “Beyond the ATP Readout: A Novel Imaging Assay to Reveal Distinct Mechanisms of Cytotoxicity in High-Throughput.”

📧 Reach out to us at info@saguarobio.com to set up a meeting and discuss how Saguaro dyes can improve your drug profiling insights with the leading cell painting approach.

Checkout our products and services at https://zurl.co/3Mh9g

See you in Stevenage! 🌵✨

Saguaro Biosciences

02/03/2026

01/29/2026

01/27/2026

01/20/2026

01/13/2026

12/22/2025

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