UVB light therapy med for Vitiligo,Psoriasis,Eczema

05/04/2023

26/10/2021

Vitiligo Growing period treatment:
1. NB UVB+hormone (oral or external use)
2. NB UVB+PP2B
3. NB UVB+Chinese herbs
4. NB UVB+Vitamin D3 derivatives external use
5. NB UVB+photosensitizer
6. NB UVB+transplant
7. NB UVB+antioxygen (oral)
8. NB UVB+ Fractional Laser
9. NB UVB+dermabrasion
this treatment combo i get is from professional dermatologist in China. i hope it could do some help...

26/10/2021

how to distinguish growing period & intact period:study about VIDA, Koebner Phenomenon, wood lamp, and try it...

22/06/2021

22/06/2021

home use narrowband uvb 311nm light therapy with brush comb,now is available for everyone.
if any question, feel free to leave me message.

18/06/2021

Narrowband UVB (NB-UVB) phototherapy for Vitiligo
132 people have indicated they have taken Narrowband UVB (NB-UVB) phototherapy
Overview
Narrowband UVB (NB-UVB) is the most widely prescribed type of phototherapy for vitiligo.1 NB-UVB may be a first-line treatment for generalized vitiligo.2 One of the oldest vitiligo treatments, NB-UVB slows the overactive growth of skin cells by repeatedly exposing skin to an artificial UVB light source.

For generalized vitiligo, NB-UVB produces better pigmentation than Psoralen + UVA (PUVA) phototherapy) with fewer side effects.2 For maximum effectiveness, NB-UVB is often prescribed in combination with topical Protopic (Tacrolimus) or vitamin D analogs such as Calcipotriene.3

NB-UVB is considered safe for children and pregnant or breastfeeding women. It can be performed in a clinic or at home with smaller, handheld devices.2

How do I take it?
For vitiligo, NB-UVB is conducted two to three times a week for just a few minutes, with exposure gradually increased over time.1 Treatment can range from three to 24 months, with a three-month resting period after one year to minimize annual UVB dose.4

Protective goggles and groin protection (underwear or towel) must be worn during treatment. Face protection is also recommended to prevent skin aging.1

Side effects
NB-UVB for vitiligo is safe when administered correctly. Mild sunburn is a common side effect, generally experienced after eight hours of treatment. Everyone who undergoes NB-UVB will develop some degree of tan.1

Severe burns, hyperpigmentation, and skin malignancies are rare.3 Although the long-term risk of NB-UVB is unknown, research shows that it is less risky than PUVA.5

18/06/2021

VITILIGO PSORASIS SEDEF VE SEBOREA DERMATIT NEDIR ?
What is vitiligo?
Key points
Vitiligo is a pigmentary disorder resulting in typically asymptomatic white macules that can appear at any time during human life and can be psychologically devastating.
It occurs in all skin types and at all ages, with equal frequencies between men and women.
Vitiligo is considered to be an autoimmune disease with an underlying genetic predisposition in the majority of cases.
Vitiligo is not caused by poor medical care.
Personal behavior or state of mind may play an important role in the disease management.
Vitiligo is never a contagious disease, but infective agents may apparently play an indirect role in some cases.
Vitiligo is not related to bad diet, but correct diet may help.
Vitiligo seems not to be directly related to pollution, but the environment plays a major role in vitiligo development.
Vitiligo is not clearly genetically transmitted.
Progression of the disease can be halted in about 90% of cases, if treatment is sought.
A cure is not yet known for each and every case, but adequate medical and /or surgical therapies may treat satisfactorily over 75% of the affected subjects.
Be optimistic! It is not true that there is nothing that can be done for vitiligo. In fact, just the opposite is true and research is happening all over the world to find the cure for vitiligo.
Vitiligo is an acquired sudden loss of the inherited skin color. Despite its long recognition, the cause of this disorder is still unknown. The loss of skin color yields white patches of various sizes, which can be localized anywhere on the body. The disease affects people of all races, men and women, and all age groups. It may appear at any age; cases have been reported as early as 6 weeks after birth and after 80 years of age.
Vitiligo is not a contagious disease, however is is a difficult condition to tolerate, being more often a psychologically devastating disease, especially in darker skinned individuals, in whom it is more easily noticeable. The actual cause of vitiligo is under debate and has been attributed to autoimmune causes, oxidative stress, and/or a neurogenic disturbance. These terms will be explained later on.
In other terms, vitiligo is a skin and/or mucosal disorder characterized by white patches, often, but not always, symmetrical, which usually increase in size with time, corresponding to a substantial loss of functioning epidermal and sometimes hair follicle melanocytes. It may occur in a unilateral distribution or may be generalized.
Vitiligo lesions may rarely itch and have a high propensity to sunburn. Vitiligo is a chronic persistent and often progressive disorder; spontaneous repigmentation is uncommon and usually occurs around the hairs in a perifollicular pattern. Many patients are poorly educated about their illness. In one study, 51.3% of patients believed that their vitiligo was caused by poor medical care, 30% thought personal behavior played a major role, 25% - wrong diet, 21.3% - altered state of mind, and 20% blamed only pollution or environmental alterations. All the beliefs mentioned above are considered by the scientific community to be “per se” unfounded and misleading, even if all of them may offer some true indications for understanding the disease and for finding the cure.
Vitiligo is a disease that presently cannot be cured, but still can be treated successfully with many different approaches. Its progression can be halted in almost 90% of cases with appropriate therapy, most frequently by combining different treatments. More than 75% of subjects affected by vitiligo respond satisfactorily to active treatments (medical or surgical).

18/06/2021

Vitiligo nbUVB Treatment Protocol
By John E. Harris, MD, PhD and Mark Scharf, MD
The success of nbUVB (311-312) therapy for vitiligo was first reported by Westerhof and Nieuweboer-Krobotova
in 1997 (1). Yones et al. reported superior efficacy of nbUVB over PUVA in 2007 (2). No evidence-based
guidelines for treatment have been reported, and current protocols are based on experience. In general, a safe,
aggressive treatment protocol is preferred to a conservative one for two reasons: 1) slow progression wastes
time for the patient, who is eager to find the dose that will induce repigmentation. 2) slow progression
encourages light adaptation in the skin, which blocks UV pe*******on and the beneficial effects, possibly
prolonging the time it takes to reach a therapeutic dose.
Frequency: Treatment frequency should be 2-3x/wk. In two separate studies comparing 2x/wk vs. 3x/wk for
vitiligo (Excimer laser)(3) and psoriasis (nbUVB)(4), 3x/weekly produced faster results than 2x/weekly, however
eventually the two schedules resulted in equivalent efficacy. Therefore, if the patient’s schedule allows, I
recommend starting at 3x/weekly for the first 3 months, and then decreasing to 2x/weekly thereafter.
Dosing: A slight pink erythema lasting less than 24 hrs is thought to be an optimal response (5), which will occur
at different light doses in different patients. The recommended starting dose for non-vitiligo treatment protocols
is typically 50-70% of the MED assessed for each patient. Assessing MED for vitiligo is difficult due to limited
involved skin, and arguably unnecessary since depigmented skin is similar to Type I skin, for which the average
MED is 400. Therefore most protocols in use recommend basing the starting dose on this standard.
Recommendations for increases at each visit are typically 5-20% of the previous dose, however many use a set
dose increase that falls within this range for early treatments. Some protocols recommend soft holding doses,
ranging from 500 – 3000 mJ/cm2 (1000 for face), however others have no set limits and have reportly used up
to 5000 mJ/cm2 There have been no reports of increased skin cancer risk using nbUVB (unlike PUVA), and
therefore there are currently no recommendations for maximum number of treatments (6).
Shielding: Shielding of sensitive anatomic sites is recommended by most protocols. A single study reported an
increased cancer risk of nbUVB to male ge****ls (7), and therefore shielding of male ge****ls during treatment is
recommended. Because female ge****ls are typically not exposed during treatment, shielding is not required.
UVB has been implicated in the formation of cataracts (8), and therefore shielding with UVB-protective goggles
is standard practice, however this prevents treatment of eyelids, with unsatisfactory results (9). Occasionally
patients will be allowed to keep their eyes closed without goggles to expose the eyelids when necessary.
Recent advances in contact lenses demonstrate the ability of Class I (Senofilcon A) soft contact lenses to block
>99% UVB light and protect rabbit cornea from adverse effects (10). Therefore, we will allow our patients with
periocular depigmentation to wear Class I soft contact lenses in place of goggles during the beginning of each
treatment session. Eyelids will be evaluated for erythema separately from the rest of the body, replacing
goggles for the remainder of the session once “eyelid dose” appropriate for the patient has been reached.
The first UMass protocol for nbUVB treatment of vitiligo (pre-2012) recommended a 200 mJ/cm2 starting dose,
increasing by 50 mJ/cm2 at each visit; missed visits resulted in a dose decrease by 50% after 1-2 weeks or
starting over after that. The following protocol was adapted by surveying other dermatology treatment centers
(Henry Ford, UPenn), reviewing the methods for nbUVB efficacy studies in the literature, and from the current
edition of Phototherapy Treatment Protocols (11). The current protocol will aim for mild erythema lasting 24-48
hrs, based on updated recommendations (11). These guidelines are subject to change, and suggestions for
modification are welcome.
References:
1. W. Westerhof, L. Nieuweboer-Krobotova, Treatment of vitiligo with UV-B radiation vs topical psoralen plus UV-A. Arch
Dermatol 133, 1525 (Dec, 1997).
2. S. S. Yones, R. A. Palmer, T. M. Garibaldinos, J. L. Hawk, Randomized double-blind trial of treatment of vitiligo: efficacy of
psoralen-UV-A therapy vs Narrowband-UV-B therapy. Arch Dermatol 143, 578 (May, 2007).
3. A. Hofer, A. S. Hassan, F. J. Legat, H. Kerl, P. Wolf, Optimal weekly frequency of 308-nm excimer laser treatment in vitiligo
patients. Br J Dermatol 152, 981 (May, 2005).
4. H. Cameron et al., A randomized, observer-blinded trial of twice vs. three times weekly narrowband ultraviolet B
phototherapy for chronic plaque psoriasis. Br J Dermatol 147, 973 (Nov, 2002).
5. T. S. Anbar, W. Westerhof, A. T. Abdel-Rahman, M. A. El-Khayyat, Evaluation of the effects of NB-UVB in both segmental
and non-segmental vitiligo affecting different body sites. Photodermatol Photoimmunol Photomed 22, 157 (Jun, 2006)
6. E. Lee, J. Koo, T. Berger, UVB phototherapy and skin cancer risk: a review of the literature. Int J Dermatol 44, 355 (May,
2005).
7. R. S. Stern, Ge***al tumors among men with psoriasis exposed to psoralens and ultraviolet A radiation (PUVA) and ultraviolet
B radiation. The Photochemotherapy Follow-up Study. N Engl J Med 322, 1093 (Apr 19, 1990).
8. H. R. Taylor et al., Effect of ultraviolet radiation on cataract formation. N Engl J Med 319, 1429 (Dec 1, 1988).
9. S. Percivalle, R. Piccinno, M. Caccialanza, S. Forti, Narrowband Ultraviolet B Phototherapy in Childhood Vitiligo: Evaluation
of Results in 28 Patients. Pediatr Dermatol, (Feb 13, 2012).
10. F. J. Giblin, L. R. Lin, V. R. Leverenz, L. Dang, A class I (Senofilcon A) soft contact lens prevents UVB-induced ocular
effects, including cataract, in the rabbit in vivo. Invest Ophthalmol Vis Sci 52, 3667 (May, 2011).
11. F. Zanolli, Phototherapy Treatment Protocols. (Taylor & Francis, New York, ed. 2nd, 2005), pp. 175.
Protocol
1. Ensure the patient has been properly consented for treatment and has signed the consent form.
2. Have the patient undress and expose the areas of vitiligo to be treated. Male patients should wear an
athletic supporter or other appropriate shielding for the ge****ls, and all patients should cover ni***es
with zinc paste unless otherwise directed or permitted by the attending physician.
3. Eye protection in the form of UV goggles OR UV-protective contact lenses (as directed by the
attending physician) must be worn by all patients when inside the phototherapy unit.
4. The irradiance (mW/cm2
) of the nbUVB light inside the unit should be recorded once monthly using the
standard method of the manufacturer of the phototherapy unit. Record this irradiance on the
phototherapy record sheet or keep an irradiance log book for the equipment used in patient care.
5. The initial nbUVB dose (mJ/cm2
) will be the same for all patients with vitiligo. It is 200 mJ/cm2
6. The manual method for calculation of the time (seconds) to set the nbUVB control panel to deliver the
dose from #5 is the following equation. The measurement of the irradiance can be obtained from the
log book kept on a monthly basis.
TIME (seconds) = DOSE (mJ/cm2
) / IRRADIANCE (mW/cm2
)
7. The duration of a treatment or total dose of nbUVB to be delivered can often be calculated by the UV
light unit by following the manufacturer’s instructions in the operations manual and inputting the correct
information on the control panel prior to the delivery of the treatment.
8. Set the time (dose) on the UV light unit. In some phototherapy units the session duration is dependent
on the dose measured by an internal photometer and the time must be estimated by the technician.
9. Verify that the UV light unit is set on nbUVB.
10. Turn on the fan and have the patient stand in the center of the UV light unit with their arms at rest or in
the best position to expose required areas. Double-check that they are wearing eye protection.
11. Instruct the patient to come out of the UV light box when the lights go out or if they become
uncomfortable during the treatment either from burning or stinging of the skin. Inform the patient that
the unit doors are not locked.
12. Start the treatment.
13. The frequency of nbUVB light treatments for the diagnosis of vitiligo is 2-3x weekly as ordered by the
attending physician.
14. On subsequent visits, ask the patient about pinkness/tenderness of the skin the previous days, and
document the response in the phototherapy record.
15. If there was no pinkness following the previous dose of nbUVB, increase the dose of UVB by 50
mJ/cm2 If the patient reports that there was pinkness or there is mild pinkness today, maintain the
dose. If there is moderate pinkness with or without pain today, decrease the dose by 25 mJ/cm2 If
there is severe pinkness/redness or there is pain, ask physician to evaluate the patient, wait until it
resolves, and restart at a 15% decreased dose. Once the ordered holding dose is reached, hold at that
dose until next evaluated by a physician, which will generally be 6-12 weeks after starting therapy. The
holding dose may be increased at that time.
16. Dose adjustments for missed treatments. If the patient has missed:
Up to 1 week – maintain previous dose
1-2 weeks - Decrease by 25%
2-3 weeks - Decrease by 50%
2-3 weeks - Decrease by 75%
> 4 weeks - Restart at 200 mJ/cm2

Vitiligo nbUVB Treatment Protocol Summary
Vitiligo starting dose = 200 mJ/cm2 (0.5 x MED for Type I skin, 400 mJ/cm2
)
Increase dose by 50 mJ/cm2 at each visit until mild erythema lasting 4 weeks Restart at 200 mJ/cm2

18/06/2021

Tiny LED lights may revolutionize UVB phototherapy for vitiligo
Phototherapy is the treatment of choice for many skin conditions today. After first introduction for psoriasis in Europe in 1988, it became widely used in the United States in the 1990s. Its innovative use in vitiligo came in 1997, but twenty-plus years later it is still an unaffordable luxury in many developing countries.

Ultraviolet type B (UVB) light is a part of sunlight that reaches the surface of Earth in abundance. When sunlight reach the skin, one part is reflected, and the other part is absorbed by the skin. UV radiation triggers various reactions in different skin layers, ranging from therapeutic to potentially lethal. The most common skin response – known as tanning – protects us from the sun, and this process is also the basis for vitiligo treatment. By the way, tanning beds in beauty salons emit mostly UVA light, not UVB and are not suitable for treatment, but increase the risk of melanoma skin cancer by nearly 60 percent.

Phototherapy involves exposing the skin to UVB light or sun for a set length of time on a regular basis, under medical supervision. Most adult patients will notice some results after 24-36 trice-weekly treatments but sometimes it takes three to four months before any repigmentation can be seen. In children, vitiligo stops progression after 12 weeks of NB-UVB treatments, while repigmentation is commonly achievedby the end of first year of treatments. An average 34 treatment visits are required to achieve 50% repigmentation.

You may encounter phototherapy devices with different technologies, such as excimer laser (308 nm), intense pulse light systems (304-308 nm), non-laser light sources (290-310 nm) and micro-focused systems (300-320 nm). Some UVB units use fluorescent UV lamps or bulbs, and others use light emitting diodes (LED) or solid state lasers. There is no difference in results whether the light used to stimulate repigmentation was generated by a laser or a filtered incandescent lamp of the same wavelength. Excimer laser may produce faster repigmentation than narrow-band UVB in early stages of treatment but in the long run they both have similar efficacy. Home phototherapy devices range from hand-held and table-top devices for localized treatment, to freestanding or “walk-in” units for a full body treatment.

Home phototherapy devices range from hand-held and table-top devices for localized treatment, to freestanding or “walk-in” units for a full body treatment.Conventional phototherapy cost is $85-$100 per treatment. Patients with extensive vitiligo and darker skin type often require 180-220 short sessions over the period of 1-1,5 years to achieve a near complete repigmentation. Starting cost of a laser treatment at $150 or more per session (depending on the size of depigmented area), patients often require 20-30 sessions. Medicare reimburses $76 per non-targeted UVB treatment, and $150-$240 per targeted UVB treatment but not for laser treatments. Home phototherapy device costs in the range of $600-$4,000 and some insurance companies will cover this cost.
Conventional phototherapy cost is $85-$100 per treatment. Patients with extensive vitiligo and darker skin type often require 180-220 short sessions over the period of 1-1,5 years to achieve a near complete repigmentation. Starting cost of a laser treatment at $150 or more per session (depending on the size of depigmented area), patients often require 20-30 sessions. Medicare reimburses $76 per non-targeted UVB treatment, and $150-$240 per targeted UVB treatment but not for laser treatments. Home phototherapy device costs in the range of $600-$4,000 and some insurance companies will cover this cost.

17/06/2021

i will upload one uvb light therapy on my ebay store, if any friends have interest, feel free to have a look and inquiry me. thanks.
my brother is using this machine for his psoriasis. very safe, very helpful. very effective.
https://www.ebay.com/itm/224500803714

16/06/2021

Vitiligo is a chronic condition involving an immune-mediated attack on melanocytes, resulting in selective dysfunction and destruction of melanocytes in skin, hair, or both.1 It is the most common cause of depigmentation worldwide with an estimated prevalence of 1–2% and no predilection for a particular age, race, or gender.1 The typical presentation is white skin patches or hair with distinct margins between normal pigmented and involved depigmented areas.1,2 The pathogenesis of vitiligo has not been clearly established but is likely multifactorial. Hypothesized causes include autoimmune processes, genetic influences, biochemical pathways, and environmental factors.1,3 The autoimmune theory is supported by strong evidence, including the clinical association of vitiligo with autoimmune disorders of various organ systems such as endocrine, gastrointestinal, and neurologic diseases.1,4,5 Vitiligo can also have a profound negative impact on quality of life (QoL) due to psychological trauma experienced by patients with vitiligo, resulting in low self-esteem, shame, depression, anxiety, and social isolation.6,7 Furthermore, vitiligo is associated with a significant economic burden involving high direct and indirect costs, ranging from work absenteeism to expenses related to accessing care.5 Given these consequences and that early disease responds best to treatment, prompt diagnosis and management of vitiligo are critical.

16/06/2021

What Is a Wood’s Lamp Examination?

A Wood’s lamp examination is a procedure that uses transillumination (light) to detect bacterial or fungal skin infections. It also can detect skin pigment disorders such as vitiligo and other skin irregularities. This procedure can also be used to determine if you have a corneal abrasion (scratch) on the surface of your eye. This test is also known as the black light test or the ultraviolet light test.

How Does It Work?
A Wood’s lamp is a small handheld device that uses black light to illuminate areas of your skin. The light is held over an area of skin in a darkened room. The presence of certain bacteria or fungi, or changes in the pigmentation of your skin will cause the affected area of your skin to change color under the light.

Some of the conditions that a Wood’s lamp examination can help diagnose include:

tinea capitis
pityriasis versicolor
vitiligo
melasma
In the case of scratches on the eye, your doctor will put a fluorecin solution in your eye, then shine the Wood’s lamp over the affected area. Abrasions or scratches will glow when the light is on it. There are no risks associated with the procedure.

15/06/2021

After white spot light cure does not become red, is this to represent to have no effect that?
NO!NO!NO!The effect of light therapy can not simply be judged by whether the white spot is reddened or not. In my return visit, I was told by the patient that how I illuminated is not reddish. Now add 5 minutes, but it' s still not red!

It' s really the most intuitive way to see if the skin is reddened after phototherapy, but it does n't work for everyone. There are many factors related to the redness of the white spots after phototherapy. The sensitivity of different parts is different. Faces, torso and other parts are easy to redden, while the joints of hands and feet are hard to light up. The darker the complexion, the less sensitive. There are seasons, age, medication, occupation, etc. can affect the sensitivity of the skin.

Blindly think that there are erythema is effective, do not see the red spot that the effect of light therapy is not good, this is unscientific. Like the limbs of these parts belong to the difficult to treat vitiligo, can be used in conjunction with some photosensitizers, need to adhere to treatment! Whether the effect of phototherapy can not only see skin lesions red not red, but to see the spot of the recovery of melanin.

Vitiligo patients can observe whether there is an increase in melanin through wood lamps, at home at any time to observe the effect of phototherapy.

With the wide application of phototherapy, the treatment equipment is more and more, patients can only choose the regular equipment to ensure the therapeutic effect more effectively.

Warm prompt: vitiligo itself is a stubborn skin disease, the recovery of the leukoplakia is required a process, must insist on treatment, not urgent. I hope you' ll have healthy skin soon.

11/06/2021

my brother was suffering with Psoriasis, and my niece also was suffering with Vitiligo, i know what they feel, and feel their pain.
someday, i know UVB phototherapy is effective for treatment, i suggest them and try, finally, cured. so glad...here i would like to share all experience and provide suggestions. always have a faith for a better life...
a

11/06/2021

Skin disease best treatment
It’s true, that you can’t cure some skin disease completely. But it’s the symptoms that ruin your life, so the solution is logical – get rid of them. Narrow Band UV radiation is proven to fight the symptoms of psoriasis, vitiligo and other not-very-pleasant skin problems.
You might have known that, but did you realize that UVB spectrum light is 92% efficient at removing any trace of the disease from your skin? Spending just a few minutes every day at home, while watching cable or reading, you can almost cure yourself! It’s not a secret or the latest research – just something the doctors don’t want you to do, because it makes them lose the appointments money. UVB lamps – safe, effective and convenient!
If you have skin problems – it’s time to make the right decision and discover the therapy you need

11/06/2021

Hello everyone, this is Leo, if you are suffering with Vitiligo Psoriasis, Eczema or any skin disorders, welcome to leave your message here or contact with me directly, share your experience, i am pleasure to assist and provide suggestions.

11/06/2021

10/06/2021