Prurigo Nodularis League

Prurigo Nodularis League Despite its prevalence and severity, prurigo nodularis remains a relatively unknown skin disease. Prurigo nodularis ist eine relativ unerforschte Erkrankung.

Our goal is to raise global awareness and provide current news relating to this debilitating illness. Hier finden Sie aktuelle News rund um das Netzwerk Prurigo nodularis Liga.

Happy Easter from the Prurigo Nodularis League ๐Ÿฐ๐Ÿ’™Wishing you a wonderful time with your family and friends, filled with ...
05/04/2026

Happy Easter from the Prurigo Nodularis League ๐Ÿฐ๐Ÿ’™

Wishing you a wonderful time with your family and friends, filled with joy, love, and good health! ๐ŸŒธ

Treatment of Chronic Prurigo ๐Ÿ‘‰ What treatment options are available?We provide a patient-friendly overview based on curr...
27/03/2026

Treatment of Chronic Prurigo

๐Ÿ‘‰ What treatment options are available?
We provide a patient-friendly overview based on current guidelines. ๐Ÿ’™

From topical therapies to modern biologics like dupilumab and nemolizumab, treatment is highly individualized.

๐Ÿ’™ Important
Managing chronic prurigo often requires a combination of different approaches.

What treatments have helped you? Share your experience below ๐Ÿ‘‡

๐Ÿ’™๐—ง๐—ฟ๐—ฒ๐—ฎ๐˜๐—บ๐—ฒ๐—ป๐˜ ๐—ผ๐—ณ ๐—–๐—ต๐—ฟ๐—ผ๐—ป๐—ถ๐—ฐ ๐—ฃ๐—ฟ๐˜‚๐—ฟ๐—ถ๐—ด๐—ผ ๐Ÿ‘‰ What treatment options are available?We provide a patient-friendly overview based on cur...
25/03/2026

๐Ÿ’™๐—ง๐—ฟ๐—ฒ๐—ฎ๐˜๐—บ๐—ฒ๐—ป๐˜ ๐—ผ๐—ณ ๐—–๐—ต๐—ฟ๐—ผ๐—ป๐—ถ๐—ฐ ๐—ฃ๐—ฟ๐˜‚๐—ฟ๐—ถ๐—ด๐—ผ

๐Ÿ‘‰ What treatment options are available?
We provide a patient-friendly overview based on current guidelines. ๐Ÿ’™

From topical therapies to modern biologics like dupilumab and nemolizumab, treatment is highly individualized.

๐Ÿ’™ ๐—œ๐—บ๐—ฝ๐—ผ๐—ฟ๐˜๐—ฎ๐—ป๐˜
Managing chronic prurigo often requires a combination of different approaches.

What treatments have helped you? Share your experience below ๐Ÿ‘‡

๐—™๐—ข๐—•๐—œ ๐Ÿฎ๐Ÿฌ๐Ÿฎ๐Ÿฒ ๐ŸŒŸ๐Ÿฏ๐Ÿฌ๐˜๐—ต ๐—”๐—ฑ๐˜ƒ๐—ฎ๐—ป๐—ฐ๐—ฒ๐—ฑ ๐—ง๐—ฟ๐—ฎ๐—ถ๐—ป๐—ถ๐—ป๐—ด ๐—ช๐—ฒ๐—ฒ๐—ธ ๐—ถ๐—ป ๐—ฃ๐—ฟ๐—ฎ๐—ฐ๐˜๐—ถ๐—ฐ๐—ฎ๐—น ๐——๐—ฒ๐—ฟ๐—บ๐—ฎ๐˜๐—ผ๐—น๐—ผ๐—ด๐˜† & ๐—ฉ๐—ฒ๐—ป๐—ฒ๐—ฟ๐—ฒ๐—ผ๐—น๐—ผ๐—ด๐˜†๐Ÿ“… ๐Ÿฌ๐Ÿฒโ€“๐Ÿญ๐Ÿฌ ๐—ข๐—ฐ๐˜๐—ผ๐—ฏ๐—ฒ๐—ฟ ๐Ÿฎ๐Ÿฌ๐Ÿฎ๐Ÿฒ | ๐— ๐˜‚๐—ป๐—ถ๐—ฐ๐—ต, ๐—š๐—ฒ๐—ฟ๐—บ๐—ฎ๐—ป๐˜†Our e...
13/03/2026

๐—™๐—ข๐—•๐—œ ๐Ÿฎ๐Ÿฌ๐Ÿฎ๐Ÿฒ ๐ŸŒŸ
๐Ÿฏ๐Ÿฌ๐˜๐—ต ๐—”๐—ฑ๐˜ƒ๐—ฎ๐—ป๐—ฐ๐—ฒ๐—ฑ ๐—ง๐—ฟ๐—ฎ๐—ถ๐—ป๐—ถ๐—ป๐—ด ๐—ช๐—ฒ๐—ฒ๐—ธ ๐—ถ๐—ป ๐—ฃ๐—ฟ๐—ฎ๐—ฐ๐˜๐—ถ๐—ฐ๐—ฎ๐—น ๐——๐—ฒ๐—ฟ๐—บ๐—ฎ๐˜๐—ผ๐—น๐—ผ๐—ด๐˜† & ๐—ฉ๐—ฒ๐—ป๐—ฒ๐—ฟ๐—ฒ๐—ผ๐—น๐—ผ๐—ด๐˜†

๐Ÿ“… ๐Ÿฌ๐Ÿฒโ€“๐Ÿญ๐Ÿฌ ๐—ข๐—ฐ๐˜๐—ผ๐—ฏ๐—ฒ๐—ฟ ๐Ÿฎ๐Ÿฌ๐Ÿฎ๐Ÿฒ | ๐— ๐˜‚๐—ป๐—ถ๐—ฐ๐—ต, ๐—š๐—ฒ๐—ฟ๐—บ๐—ฎ๐—ป๐˜†

Our experts from the ๐—–๐—ผ๐—บ๐—ฝ๐—ฒ๐˜๐—ฒ๐—ป๐—ฐ๐—ฒ ๐—ณ๐—ผ๐—ฟ ๐—–๐—ต๐—ฟ๐—ผ๐—ป๐—ถ๐—ฐ ๐—ฃ๐—ฟ๐˜‚๐—ฟ๐—ถ๐˜๐˜‚๐˜€ ๐—–๐—ฒ๐—ป๐˜๐—ฒ๐—ฟ ๐—ฎ๐˜ ๐˜๐—ต๐—ฒ ๐—จ๐—ป๐—ถ๐˜ƒ๐—ฒ๐—ฟ๐˜€๐—ถ๐˜๐˜† ๐—›๐—ผ๐˜€๐—ฝ๐—ถ๐˜๐—ฎ๐—น ๐— รผ๐—ป๐˜€๐˜๐—ฒ๐—ฟ will be presenting lectures on pruritus and prurigo:

๐Ÿ‘ฉโ€โš•๏ธ ๐—ฆ๐—ผ๐—ป๐—ท๐—ฎ ๐—ฆ๐˜รค๐—ป๐—ฑ๐—ฒ๐—ฟ
๐Ÿ‘ฉโ€โš•๏ธ ๐—–๐—น๐—ฎ๐˜‚๐—ฑ๐—ถ๐—ฎ ๐—ญ๐—ฒ๐—ถ๐—ฑ๐—น๐—ฒ๐—ฟ

๐Ÿ’ก ๐—ช๐—ฒ๐—ฑ๐—ป๐—ฒ๐˜€๐—ฑ๐—ฎ๐˜†: Hands-on course on practical disease management & modern therapy options for pruritus.

๐Ÿ’ก ๐—ช๐—ฒ๐—ฑ๐—ป๐—ฒ๐˜€๐—ฑ๐—ฎ๐˜† & ๐—™๐—ฟ๐—ถ๐—ฑ๐—ฎ๐˜†: Further lectures on pathophysiology, current guidelines, and therapy options for pruritus and prurigo. (Check the next slide for the full program!)

We look forward to your participation and an inspiring professional exchange! ๐Ÿคโœจ

Prurigo nodularis (PN) typically affects the extensor surfaces of the arms, legs, and trunkโ€”areas prone to repeated scra...
12/03/2026

Prurigo nodularis (PN) typically affects the extensor surfaces of the arms, legs, and trunkโ€”areas prone to repeated scratching.

The palms, however, are a rare site. Their thick stratum corneum, absence of hair follicles, and distinct neural and immune microenvironment usually protect them from developing classic PN nodules. As a result, palmar PN is frequently overlooked or misdiagnosed, most commonly as palmoplantar pustulosis or viral warts.

In this remarkable case, a 58-year-old woman suffered from 15 years of severe palmar pruritus and nodules, significantly impairing hand function and quality of life. Persistent scratching eventually led to disease spread beyond the palms.

Only through careful clinical evaluation, histopathology, and immunological assessment was the correct diagnosis established:
Prurigo nodularis with predominant palmar involvementโ€”a presentation rarely reported in the literature.

Targeted therapy with high-potency topical corticosteroids under occlusion, combined with antihistamines, successfully interrupted the itchโ€“scratch cycle, resulting in rapid improvement and sustained remission.

๐Ÿ“ Miyamoto et al.
๐Ÿ—“๏ธ Indian Journal of Dermatology, Venereology and Leprology, Epub November 2025

โœจ Take-home message: When chronic itch persists in an unexpected location, thinking beyond typical patterns can be life-changing for patients.

๐—ก๐—ฒ๐—บ๐—ผ๐—น๐—ถ๐˜‡๐˜‚๐—บ๐—ฎ๐—ฏ ๐—ฎ๐—ป๐—ฑ ๐˜๐—ต๐—ฒ ๐—ฆ๐—ธ๐—ถ๐—ป ๐— ๐—ถ๐—ธ๐—ฟ๐—ผ๐—ฏ๐—ถ๐—ผ๐—บ๐—ฒ ๐—ถ๐—ป ๐—–๐—ต๐—ฟ๐—ผ๐—ป๐—ถ๐—ฐ ๐—ฃ๐—ฟ๐˜‚๐—ฟ๐—ถ๐—ด๐—ผ In a recent study, Zhou et al. 2026 investigated the influence of...
05/03/2026

๐—ก๐—ฒ๐—บ๐—ผ๐—น๐—ถ๐˜‡๐˜‚๐—บ๐—ฎ๐—ฏ ๐—ฎ๐—ป๐—ฑ ๐˜๐—ต๐—ฒ ๐—ฆ๐—ธ๐—ถ๐—ป ๐— ๐—ถ๐—ธ๐—ฟ๐—ผ๐—ฏ๐—ถ๐—ผ๐—บ๐—ฒ ๐—ถ๐—ป ๐—–๐—ต๐—ฟ๐—ผ๐—ป๐—ถ๐—ฐ ๐—ฃ๐—ฟ๐˜‚๐—ฟ๐—ถ๐—ด๐—ผ

In a recent study, Zhou et al. 2026 investigated the influence of nemolizumab treatment on the skin microbiome. They confirmed the dominance of a special bacterium, calles Staphylococcus aureus, in the lesional skin of prurigo nodularis patients ๐Ÿฆ .

Furthermore, they were able to show that nemolizumab leads to a normalization of the microbiome, specifically the composition of the microbiome. This demonstrates the importance of microbiome studies and the interconnectedness of various parameters in skin homeostasis.

Full text can be found: https://pubmed.ncbi.nlm.nih.gov/40571154/

Chronic prurigo affects more than just the skin ๐Ÿ’™ Trigger awareness, stress management, social support, and healthy dail...
24/02/2026

Chronic prurigo affects more than just the skin ๐Ÿ’™

Trigger awareness, stress management, social support, and healthy daily routines can make a real difference ๐ŸŒฟ

In this post, we share practical tips of our patients for you to to help you support your overall well-being.

Youโ€™re not alone ๐Ÿค

๐‘ฌ๐’™๐’„๐’Š๐’•๐’Š๐’๐’ˆ ๐‘จ๐’๐’๐’๐’–๐’๐’„๐’†๐’Ž๐’†๐’๐’•!We are delighted to announce that Dr. Sonja Stรคnder will once again be speaking at the ๐€๐€๐ƒ ๐€๐ง๐ง๐ฎ๐š๐ฅ ...
10/02/2026

๐‘ฌ๐’™๐’„๐’Š๐’•๐’Š๐’๐’ˆ ๐‘จ๐’๐’๐’๐’–๐’๐’„๐’†๐’Ž๐’†๐’๐’•!

We are delighted to announce that Dr. Sonja Stรคnder will once again be speaking at the ๐€๐€๐ƒ ๐€๐ง๐ง๐ฎ๐š๐ฅ ๐Œ๐ž๐ž๐ญ๐ข๐ง๐  ๐Ÿ๐ŸŽ๐Ÿ๐Ÿ”, taking place in Denver, March 27โ€“31, 2026!
As an internationally recognized expert in dermatology, she will present her talk
โ€œWhen stress gets under your skinโ€ on March 30,
highlighting how stress impacts the skin and exploring emerging therapeutic approaches.
Donโ€™t miss this opportunity to gain valuable insights at the intersection of stress, skin, and innovative treatment strategies!

๐Ÿฉบ ๐——๐—ถ๐—ฎ๐—ด๐—ป๐—ผ๐˜€๐—ถ๐—ป๐—ด ๐—–๐—ต๐—ฟ๐—ผ๐—ป๐—ถ๐—ฐ ๐—ฃ๐—ฟ๐˜‚๐—ฟ๐—ถ๐—ด๐—ผChronic prurigo is mainly a clinical diagnosis, based on the typical appearance of persisten...
30/01/2026

๐Ÿฉบ ๐——๐—ถ๐—ฎ๐—ด๐—ป๐—ผ๐˜€๐—ถ๐—ป๐—ด ๐—–๐—ต๐—ฟ๐—ผ๐—ป๐—ถ๐—ฐ ๐—ฃ๐—ฟ๐˜‚๐—ฟ๐—ถ๐—ด๐—ผ

Chronic prurigo is mainly a clinical diagnosis, based on the typical appearance of persistent, itchy nodules. A thorough skin examination is key, and skin biopsy may be considered in unclear cases. Assessment of itch severity and impact on daily life can guide treatment.

๐—–๐—ต๐—ฟ๐—ผ๐—ป๐—ถ๐—ฐ ๐—ฃ๐—ฟ๐˜‚๐—ฟ๐—ถ๐—ด๐—ผ ๐—ฎ๐—ณ๐—ณ๐—ฒ๐—ฐ๐˜๐˜€ ๐—บ๐—ผ๐—ฟ๐—ฒ ๐˜๐—ต๐—ฎ๐—ป ๐—ท๐˜‚๐˜€๐˜ ๐˜๐—ต๐—ฒ ๐˜€๐—ธ๐—ถ๐—ป โ€“ ๐—ถ๐˜ ๐—ถ๐—บ๐—ฝ๐—ฎ๐—ฐ๐˜๐˜€ ๐˜†๐—ผ๐˜‚๐—ฟ ๐—ฏ๐—ผ๐—ฑ๐˜†, ๐—บ๐—ถ๐—ป๐—ฑ, ๐—ฎ๐—ป๐—ฑ ๐—ฑ๐—ฎ๐—ถ๐—น๐˜† ๐—น๐—ถ๐—ณ๐—ฒ. ๐Ÿ˜”๐Ÿ’™ What challenges do you ...
24/01/2026

๐—–๐—ต๐—ฟ๐—ผ๐—ป๐—ถ๐—ฐ ๐—ฃ๐—ฟ๐˜‚๐—ฟ๐—ถ๐—ด๐—ผ ๐—ฎ๐—ณ๐—ณ๐—ฒ๐—ฐ๐˜๐˜€ ๐—บ๐—ผ๐—ฟ๐—ฒ ๐˜๐—ต๐—ฎ๐—ป ๐—ท๐˜‚๐˜€๐˜ ๐˜๐—ต๐—ฒ ๐˜€๐—ธ๐—ถ๐—ป โ€“ ๐—ถ๐˜ ๐—ถ๐—บ๐—ฝ๐—ฎ๐—ฐ๐˜๐˜€ ๐˜†๐—ผ๐˜‚๐—ฟ ๐—ฏ๐—ผ๐—ฑ๐˜†, ๐—บ๐—ถ๐—ป๐—ฑ, ๐—ฎ๐—ป๐—ฑ ๐—ฑ๐—ฎ๐—ถ๐—น๐˜† ๐—น๐—ถ๐—ณ๐—ฒ. ๐Ÿ˜”๐Ÿ’™

What challenges do you face living with this skin condition? Tell us your story.
๏ฟฝ

๐—ฆ๐˜†๐—บ๐—ฝ๐˜๐—ผ๐—บ๐˜€ ๐—ผ๐—ณ ๐—–๐—ต๐—ฟ๐—ผ๐—ป๐—ถ๐—ฐ ๐—ฃ๐—ฟ๐˜‚๐—ฟ๐—ถ๐—ด๐—ผTypical symptoms of chronic prurigo include persistent pruriginous symptoms and intensely pru...
17/01/2026

๐—ฆ๐˜†๐—บ๐—ฝ๐˜๐—ผ๐—บ๐˜€ ๐—ผ๐—ณ ๐—–๐—ต๐—ฟ๐—ผ๐—ป๐—ถ๐—ฐ ๐—ฃ๐—ฟ๐˜‚๐—ฟ๐—ถ๐—ด๐—ผ

Typical symptoms of chronic prurigo include persistent pruriginous symptoms and intensely pruriginous skin lesions.

๐Ÿ‘‰ Important to know: you are not alone โ€” chronic prurigo is a medical condition.

๐—ฃ๐—ฟ๐˜‚๐—ฟ๐—ถ๐˜๐˜‚๐˜€-๐—”๐˜€๐˜€๐—ผ๐—ฐ๐—ถ๐—ฎ๐˜๐—ฒ๐—ฑ ๐—ฆ๐˜๐—ฟ๐—ฒ๐˜€๐˜€ ๐—ฆ๐—ฐ๐—ฎ๐—น๐—ฒ (๐—ฃ๐—”๐—ฆ๐—ฆ)Chronic itch is more than a skin symptom โ€” it can be stressful, exhausting, and e...
09/01/2026

๐—ฃ๐—ฟ๐˜‚๐—ฟ๐—ถ๐˜๐˜‚๐˜€-๐—”๐˜€๐˜€๐—ผ๐—ฐ๐—ถ๐—ฎ๐˜๐—ฒ๐—ฑ ๐—ฆ๐˜๐—ฟ๐—ฒ๐˜€๐˜€ ๐—ฆ๐—ฐ๐—ฎ๐—น๐—ฒ (๐—ฃ๐—”๐—ฆ๐—ฆ)

Chronic itch is more than a skin symptom โ€” it can be stressful, exhausting, and emotionally draining. ๐Ÿ˜ฃ๐Ÿ’ญ

๐Ÿ“Š In a recent pilot study, ๐Ÿต๐Ÿฐ.๐Ÿฑ% ๐—ผ๐—ณ ๐—ฝ๐—ฎ๐˜๐—ถ๐—ฒ๐—ป๐˜๐˜€ ๐˜„๐—ถ๐˜๐—ต ๐—ฐ๐—ต๐—ฟ๐—ผ๐—ป๐—ถ๐—ฐ ๐—ฝ๐—ฟ๐˜‚๐—ฟ๐—ถ๐˜๐˜‚๐˜€ reported that their itch caused ๐˜€๐—ถ๐—ด๐—ป๐—ถ๐—ณ๐—ถ๐—ฐ๐—ฎ๐—ป๐˜ ๐—ฑ๐—ถ๐˜€๐˜๐—ฟ๐—ฒ๐˜€๐˜€ within the last two weeks.

Thatโ€™s why researchers developed the ๐—ฃ๐—ฟ๐˜‚๐—ฟ๐—ถ๐˜๐˜‚๐˜€-๐—”๐˜€๐˜€๐—ผ๐—ฐ๐—ถ๐—ฎ๐˜๐—ฒ๐—ฑ ๐—ฆ๐˜๐—ฟ๐—ฒ๐˜€๐˜€ ๐—ฆ๐—ฐ๐—ฎ๐—น๐—ฒ (๐—ฃ๐—”๐—ฆ๐—ฆ)โ€” a questionnaire designed specifically to assess ๐—ถ๐˜๐—ฐ๐—ต-๐—ฟ๐—ฒ๐—น๐—ฎ๐˜๐—ฒ๐—ฑ ๐—ฑ๐—ถ๐˜€๐˜๐—ฟ๐—ฒ๐˜€๐˜€ ๐Ÿ“.

PASS focuses on feelings such as nervousness, tension, mental exhaustion, fatigue, and the urge to scratch more when feeling distressed.

This matters because ๐—ด๐—ฒ๐—ป๐—ฒ๐—ฟ๐—ฎ๐—น ๐˜€๐˜๐—ฟ๐—ฒ๐˜€๐˜€ ๐—พ๐˜‚๐—ฒ๐˜€๐˜๐—ถ๐—ผ๐—ป๐—ป๐—ฎ๐—ถ๐—ฟ๐—ฒ๐˜€ ๐—ผ๐—ณ๐˜๐—ฒ๐—ป ๐—ณ๐—ฎ๐—ถ๐—น ๐˜๐—ผ ๐—ฐ๐—ฎ๐—ฝ๐˜๐˜‚๐—ฟ๐—ฒ ๐˜„๐—ต๐—ฎ๐˜ ๐—บ๐—ฎ๐—ธ๐—ฒ๐˜€ ๐—ถ๐˜๐—ฐ๐—ต-๐—ฟ๐—ฒ๐—น๐—ฎ๐˜๐—ฒ๐—ฑ ๐—ฑ๐—ถ๐˜€๐˜๐—ฟ๐—ฒ๐˜€๐˜€ ๐˜‚๐—ป๐—ถ๐—พ๐˜‚๐—ฒ.

With PASS, clinicians can better recognize the hidden burden of chronic itch and identify when distress is contributing to worsening symptoms.

It also allows treatment success to be measured not only by โ€œless itchโ€, but by โ€œless distress caused by itch.โ€

๐Ÿ”— ๐—ฅ๐—ฒ๐—ณ๐—ฒ๐—ฟ๐—ฒ๐—ป๐—ฐ๐—ฒ ๐—ฐ๐—ฎ๐—ป ๐—ฏ๐—ฒ ๐—ณ๐—ผ๐˜‚๐—ป๐—ฑ ๐—ต๐—ฒ๐—ฟ๐—ฒ:
https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1683259/full

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