MC Nursing and Aesthetic Clinic

23/08/2025

Learning curve never finish:

23/08/2025

In this clinic we are providing botox only for cosmetic purposes.
We are NOT providing (yet) neurotoxins for neutologic purposes
For your information, Botulinum Toxin it is used in Neurology:

Therapeutic Applications & Mechanisms

1. Mechanism of Action
Botulinum toxin (BoNT) acts by:
Presynaptic inhibition at neuromuscular junctions → blocks acetylcholine (ACh) release
Cleaves SNARE proteins (SNAP-25, VAMP, syntaxin) → prevents vesicle fusion
Effects last 3-6 months (until nerve terminals regenerate)

2. FDA-Approved Neurological Uses
A. Chronic Migraine
Injection Sites: 31-39 sites across frontal, temporal, occipital, and cervical muscles
Dose: 155-195 units (Botox®) q12 weeks
Efficacy: ~50% reduction in headache days/month
B. Spasticity (Post-Stroke, CP, MS)
Targets: Gastrocnemius (foot drop), biceps (flexor spasticity), adductors
Dose: 50-400 units per muscle (individualized)
Combines with PT/OT for best outcomes
C. Dystonia
Cervical dystonia (torticollis): Sternocleidomastoid, splenius capitis
Blepharospasm: Orbicularis oculi
Writer’s cramp: Forearm flexors
D. Hyperhidrosis (Excessive Sweating)
Palmar/axillary: 50-100 units per area
Effect: Anhidrosis for 4-12 months

3. Off-Label but Evidence-Based Uses
Trigeminal Neuralgia (masseter/temporalis injections)
Neurogenic Detrusor Overactivity (bladder injections)
Tremor (refractory essential tremor, dystonic tremor)
Bruxism (masseter injections)

4. Practical Considerations
Peak Effect: 2-4 weeks post-injection
Adverse Effects:
Local weakness (e.g., ptosis in blepharospasm)
Dysphagia (if neck muscles injected)
Dry mouth (migraine protocol)
Contraindications:
Myasthenia gravis, ALS, Lambert-Eaton syndrome
Allergy to BoNT components

5. Future Directions
Newer Toxins: IncobotulinumtoxinA (longer duration)
Non-motor Applications: Depression (facial feedback hypothesis), neuropathic pain

14/08/2025

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🔹 Personalised plan with NMC-registered nurse prescriber
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📍 Bedford MK43 | 💬 Text: 07756 668153
🌐 www.mirelacare.com



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14/08/2025

✨ Melt Away Stubborn Fat – Safely & Effectively! ✨
Transform your body contour with our *advanced fat-dissolving treatments* at *MirelaCare Aesthetic & Nursing Clinic* – Bedford MK43.

💉 Offering a full range of premium products:
- Lemon Bottle – Fast-acting, natural ingredients
- Infini Lipomax – Gentle with powerful results
- Aqualyx – Clinically proven for localized fat
- Desobody– Perfect for larger body areas
- Desoface – Designed specifically for facial contouring
- Other CE-marked brands also available on consultation

🔹 Targets: double chin, stomach, thighs, arms, back, flanks & more
🔹 Non-surgical, minimal downtime
🔹 Personalised plan with NMC-registered nurse prescriber
🔹 Fully insured, medical-grade care

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13/08/2025

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13/08/2025

https://www.facebook.com/share/p/19D7K3ekBJ/

02/08/2025

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31/07/2025

https://www.facebook.com/share/p/15qykMeYpY/

Anyone undergoing a cosmetic procedure is warned to be aware of the signs and symptoms of botulism, after a small number of individuals suffered adverse reactions following procedures involving botulinum toxin.

The cases are in addition to those recently diagnosed in the North East region and relate to procedures carried out in the East of England and East Midlands. To date, 38 cases of iatrogenic botulism have been reported between 4 June and 14 July.

As yet there are no known links between the newly diagnosed cases and those in the North East.

The UK Health Security Agency (UKHSA) says that evidence so far suggests the use of an unlicensed Botox-like product. It is understood that those practitioners involved in this latest incident have ceased the procedure and are co-operating with the ongoing investigation.

Reactions have included:

*Difficulty swallowing

*Slurred speech

*Breathing difficulty requiring respiratory support.

Dr Gauri Godbole, Consultant Medical Microbiologist at the UKHSA, said; "We are working closely with our partners to reduce the public health risk and would advise people to make sure they take precautions when seeking aesthetic procedures.

"Botulism related to aesthetic procedures is rare, but it can be serious. It is caused by toxins produced by the bacterium Clostridium botulinum. These toxins (but not the bacteria) are the active ingredient in ‘Botox’ and similar products.

"Symptoms of botulism can take up to 4 weeks to develop and if you have had a recent botulinum toxin (Botox-like) treatment and are having symptoms such as difficulty swallowing or breathing, contact NHS 111 for further advice and seek treatment."

If you are considering having a cosmetic procedure, please make sure to check that your practitioner is using a licensed product. On the NHS website there is more information on what sensible steps you can take when finding a practitioner.

30/07/2025

04/11/2024

Sclerotherapy involves injecting a chemical solution directly into the varicose or spider vein. The solution causes the vein walls to swell, stick together and seal shut, stopping the flow of blood. As a result, the vein fades within a few weeks.
The results of sclerotherapy are both permanent and temporary. These results can be permanent because veins that are treated will fade away, but because new spider of varicose veins can develop over time, the results are also temporary.
You'll feel the needle pinch your skin, and possibly a mild burning feeling. You may feel mild discomfort when the injection goes into your veins. In larger veins, you may feel cramping for a minute or two during the injection.
Many cases of spider and varicose veins can be treated with a single sclerotherapy treatment session. However, larger, more complicated cases may need several.
Optimal results will happen after two to four treatments, with most patients achieving over 80% elimination of the targeted spider or varicose veins.
This solution has an approximately 95% success rate in removing small varicose veins, as well as spider veins .
If you have an infection on the skin, a history of certain clotting issues or blood clots that require regular attention then you may also be unsuitable for this treatment.
You may have bruising on your legs for 10 to 14 days after your treatment. This is normal. You may also have some swelling (inflammation) or red raised patches of skin. This is normal and usually lasts 7 to 14 days after your treatment. Your veins may look darker in color, be slightly sore or both