20/11/2024
According to a study published in JAMA Dermatology, women who use contraceptive pills (OCP) may be at a higher risk for frontal fibrosing alopecia (FFA).
The researchers collected data on 489 women with FFA, 75.7% of which had a history of OCP use. These women were matched with 34,254 controls, 91% of which reported previous OCP use.
Results showed that the presence of the risk allele in CYP1B1 was associated with FFA risk.
Women who previously used OCPs were 1.9 times more likely to experience the association, whereas women without a history of OCPs were not.
“The findings suggest that OCP use may represent an environmental exposure that is associated with increased FFA risk,” the authors concluded.