IMS Epidemiology

IMS Epidemiology Research to improve population health in the UK and around the world, at the University of Cambridge.

Formerly the MRC Epidemiology Unit - https://linktr.ee/imsepidemiology Obesity, type 2 diabetes and related metabolic disorders present a major and growing global public health challenge. These disorders result from a complex interplay between genetic, developmental, behavioural and environmental factors that operate throughout life. The mission of the MRC Epidemiology Unit is to investigate the individual and combined effects of these factors and to develop and evaluate strategies to prevent these diseases and their consequences. In this way, we are working to improve the health of people in the UK and around the world. We are a Medical Research Council Unit embedded as a department of the University of Cambridge School of Clinical Medicine. The Unit is part of the Wellcome – MRC Institute of Metabolic Science (IMS) on the Cambridge Biomedical Campus, where the principle offices and laboratories of the Unit are physically located. Unit Director Professor Nick Wareham is Co-Director of the IMS with Professor Sir Stephen O’Rahilly. Being embedded in the IMS is critical to our aspiration to follow up associations between exposures and metabolic disease outcomes to determine possible causality and mechanisms. The Unit is also a part of Cambridge Population Health Sciences, a three department partnership of the Department of Public Health and Primary Care and the MRC Biostatistics Unit. Collectively, the Partnership pursues a wide range of research across epidemiology, biostatistics, population health and primary care, and delivers the Masters courses in Population Health Sciences. We are delivering on our mission through eight High Level Objectives which connect all our research programmes and infrastructure.

- To investigate the causes of obesity, diabetes and related metabolic disorders
- To develop understanding of mechanisms identified by population-based studies
- To develop and evaluate individual level approaches to the prevention of diabetes, obesity and related metabolic disorders in children and adults
- To inform, develop and evaluate population-based approaches to improving health
- To develop new methods, resources and tools for epidemiological and public health research
- To investigate approaches to improving global health, particularly in low and middle income countries
- To build capacity for conducting, understanding and using local, national, and international epidemiology and public health research
- To contribute to the translation of research evidence into policy and practice

The main objectives of each individual research programme are mapped to one or more of these High Level Objectives, which therefore provide a unifying framework to illustrate and augment the cross-links and collaborations between programmes.

Nipping at the successful heels of weight-loss drugs such as semaglutide and tirzepatide is the growing concern the poun...
09/04/2026

Nipping at the successful heels of weight-loss drugs such as semaglutide and tirzepatide is the growing concern the pounds shed will be rapidly regained.

IMS Epidemiology’s Dr Marie Spreckley is quoted in the BBC Future’s article, highlighting concerns that a lack of behavioural and lifestyle support for those on weight-loss drugs can lead to further issues.

"You don't want to have longer-term unintended consequences, like frailty and muscle loss. We don't want to replace one health concern with another."

Read the full BBC Future – https://buff.ly/OTpSvPq

Fat, what is it and does our body need it?IMS Epidemiology’s Professor Nita Forouhi tackles one of nutrition’s complicat...
08/04/2026

Fat, what is it and does our body need it?

IMS Epidemiology’s Professor Nita Forouhi tackles one of nutrition’s complicated topics in an episode of the BBC’s What’s Up Doc podcast series.

Drs Chris and Xand van Tulleken and Nita discuss separating evidence from hype and offer a clearer way to think about fat, cholesterol, and healthy eating.

Listen - https://buff.ly/5OROSxy

Concurrent Changes in Diet Quality and Physical Activity and Association with Adiposity in Adults - https://buff.ly/ZjJacDF

What are the impacts of food insecurity during the first 1,000 days of life?Join Dr Cara Ruggiero& Dr. Marie Spreckley o...
25/03/2026

What are the impacts of food insecurity during the first 1,000 days of life?

Join Dr Cara Ruggiero& Dr. Marie Spreckley of the University of Cambridge this Thursday for a free in-person Cambridge Festival talk to explores insights from the SPROUT study.

When: 26 March 2026, 6 PM
Where: Old Divinity School, St John’s College, Cambridge CB2 1TP

See link in comment for registration.

The Medical Research Council (MRC) Epidemiology Unit is now Institute of Metabolic Science (IMS) Epidemiology, Universit...
25/03/2026

The Medical Research Council (MRC) Epidemiology Unit is now Institute of Metabolic Science (IMS) Epidemiology, University of Cambridge – or IMS Epidemiology for short.

This change follows the Medical Research Council’s decision to no longer directly fund Units. For many years we have been successful in securing a range of investments from the MRC and other funders, meaning that our work continues under our new identity. Our science remains central to improving the health of populations. We are building understanding of how the interplay of our biology, behaviour and environment can contribute to obesity, type 2 diabetes, and other non-communicable diseases. We are using that knowledge to inform, develop and evaluate approaches that can improve the lives of people in the UK and around the world.

As a founding member of the Institute of Metabolic Science at the University of Cambridge, our name and branding now more clearly reflects this established collaboration of scientists and healthcare practitioners seeking to understand and improve health.

You will see changes to our websites and other resources, but you can continue to keep up to date with us in the same ways as before.

Click here to learn more: https://buff.ly/hTNlfYr

Sign up to our newsletter epigram for the latest news: https://buff.ly/detvS9w
Find all our news, events and social media channels via https://buff.ly/uPdckFY

IMS Epidemiology seeks to appoint a Programme Manager within the Global Health team.The position is part of the Cambridg...
23/03/2026

IMS Epidemiology seeks to appoint a Programme Manager within the Global Health team.

The position is part of the Cambridge Africa Diaspora Centre for Healthy, Hopeful Urban Futures (UrbanBetter Academy @ Cambridge), led by Professor Tolullah Oni.

The primary role of this post is to lead the management of research, training and convening projects and partnerships across Cambridge and African institutions. The role combines project management and delivery, partnership coordination, financial and donor management, and research governance oversight.

Closing date 2nd April 2026

Full details https://buff.ly/k5HTmyl

A Cambridge Festival speaker spotlight article talks with Dr Cara Ruggiero and Dr Marie Spreckley about insights from th...
20/03/2026

A Cambridge Festival speaker spotlight article talks with Dr Cara Ruggiero and Dr Marie Spreckley about insights from the SPROUT study into food insecurity, family systems & responsive feeding practices during the first 1,000 days of life.

Cara and Marie will share further insights from the SPROUT study in a free Cambridge Festival talk on Thursday 26 March at 6pm in the Old Divinity School at St John’s College.

Read the Cambridge Festival speaker spotlight article:https://buff.ly/wsMbQbY

Register to attend the talk on 26th March: https://buff.ly/SRMHqfN

Mandatory folic acid fortification has not yet been implemented in the UK, with concerns raised about effect of high fol...
13/03/2026

Mandatory folic acid fortification has not yet been implemented in the UK, with concerns raised about effect of high folate on vitamin B12 status.

Analysis by Dr Albert Koulman and colleagues of samples from 39,374 in UK finds young women are especially a risk of low folate status, but there is no evidence that high folate negatively affects vitamin B12 status.

Read the European Journal of Nutrition paper in the comment below.

Unit Professor Nita Forouhi and Professor Giles Yeo at the IMS-Metabolic Reseach Laboratories return to join Professor B...
04/03/2026

Unit Professor Nita Forouhi and Professor Giles Yeo at the IMS-Metabolic Reseach Laboratories return to join Professor Brian Cox to for a deeper dive into the science of nutrition on the BBC - @ The Francis Crick Institute Question of Science podcast.

Link in comment below.

Paediatricians in the UK are prescribing obesity management medications e.g. GLP-1s to children and adolescents for whom...
18/02/2026

Paediatricians in the UK are prescribing obesity management medications e.g. GLP-1s to children and adolescents for whom lifestyle interventions by themselves are not enough.

Researchers from the University of Cambridge, University College London, and the University of Southampton comment on the necessity of keeping nutrition at the heart of management medications for children and adolescents.

Dr Cara Ruggiero - University of Cambridge
Dr Marie Spreckley - University of Cambridge
Dr Nikki Davis - University of Southampton
Dr Adrian Brown - University College London (UCL)

Find out more in our blog - https://buff.ly/LS68rwH

In this free in-person Cambridge Festival talk, Dr Cara Ruggiero & Dr Marie Spreckley of the University of Cambridge wil...
17/02/2026

In this free in-person Cambridge Festival talk, Dr Cara Ruggiero & Dr Marie Spreckley of the University of Cambridge will share insights from the SPROUT study into the impacts of food insecurity during the first 1,000 days of life.

When: 26 March 2026, 6 PM
Where: Old Divinity School, St John’s College, Cambridge CB2 1TP

Registration link to attend this event in the comment below

Join our hybrid Bradford Hill Seminar 'Leveraging External Data for Testing Experimental Therapies with Biomarker Intera...
04/02/2026

Join our hybrid Bradford Hill Seminar 'Leveraging External Data for Testing Experimental Therapies with Biomarker Interactions in Randomized Clinical Trials' with Professor Lorenzo Trippa, Harvard T.H. Chan School of Public Health and Dana-Farber Cancer Institute

When: Friday 27 February, 1 PM

Attend in-person: Large Downstairs Teaching Room, East Forvie Building, Forvie Site, Robinson Way, Cambridge CB2 0SR.

Attend online: Regester on Zoom

For more information and registration see comment below.

Address

IMS Epidemiology, University Of Cambridge School Of Clinical Medicine, Box 285 Institute Of Metabolic Science, Cambridge Biomedical Campus
Cambridgeshire
CB20QQ

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