Jacqui Mayes Nutritional Therapy

16/03/2026

So many people are either using or considering using GLP-1 medication for weight loss, but this is not a long term solution, particularly as we are now beginning to understand the negative effects that this has on bone density, gut motility, digestion etc. Supporting your body's own production of GLP-1 is easier that you would think.

Did you know GLP-1 is a hormone your body makes naturally? 🧬

GLP-1 is released in the gut after you eat. It helps regulate appetite, blood sugar, and how quickly food leaves the stomach.

Meals rich in protein and fiber tend to increase satiety hormones like GLP-1. Walking after meals helps the body handle glucose more efficiently. Regular exercise, good sleep, and limiting ultra-processed foods all support the metabolic pathways that regulate hunger and blood sugar.

These habits are part of the biological foundation that helps your metabolism work the way it was designed to. Which one will you try first?

08/03/2026

Cooking is your way out of sickness, and your path to freedom from processed food and towards vibrant health and a happier life. ⁣
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When we cook, we not only nourish our bodies and souls, but we also rebuild our communities, strengthen the bonds within our families and it’s fun! ⁣
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What will you be cooking tonight?⁣

06/03/2026

Why does chronic pain often need more than one type of treatment?

Persistent pain is rarely influenced by just one factor. Muscles, joints, the nervous system, stress, sleep and daily movement patterns can all play a role in how pain develops and continues.

That’s why effective pain management often benefits from a multidisciplinary approach, where different healthcare professionals work together to support different aspects of recovery.

At The Open Practice, our upcoming 8-week Multidisciplinary Pain Management Programme brings together clinicians from several disciplines to provide coordinated, evidence-informed support for people living with persistent pain.

By addressing movement, function, psychological factors and overall wellbeing together, our aim is to help people better understand their pain and build confidence in managing it.

You can learn more about the programme and how to enquire on our website below.

https://www.theopen-practice.co.uk/researchprojects

04/03/2026

A truly fantastic programme, designed to reduce pain and restore health

Introducing our Multidisciplinary Pain Management Programme!

Living with persistent pain can be incredibly challenging, and it is rarely influenced by just one factor. Influences such as movement, the nervous system, stress, sleep and overall health can all play a role.

At The Open Practice, we’re launching a new 8-week Multidisciplinary Pain Management Programme, designed to support people living with long-term pain through a collaborative approach from clinicians across multiple disciplines.

Following an initial triage assessment, participants receive tailored support from our multidisciplinary team, which may include physiotherapy, ACT and mindfulness approaches, nutritional guidance and other clinical input where appropriate.

Our aim is to help individuals better understand their pain, improve daily function and build confidence in managing their health.

If you’d like to learn more about the programme, including suitability, pricing and how to enquire, please visit the page below:

https://lnkd.in/eyCK9xgq

18/02/2026

Women need to tend to their gut health even more as they approach menopause and after it in the postmenopausal period of their lives. Menopause-related estrogen decline reshapes the gut microbiome, reducing beneficial bacteria and increasing inflammation, intestinal permeability, and the risk of metabolic syndrome.

What's the takeaway? Personalized dietary patterns rich in fiber, polyphenols, and healthy fats, such as Mediterranean or plant-forward approaches, can help restore microbial balance and support metabolic health in postmenopausal women.

10/01/2026

https://www.politicshome.com/members/article/nutrition-cornerstone-lasting-health-weight-management-happens-glp1-medications-wear-off?fbclid=IwQ0xDSwPO54NleHRuA2FlbQIxMQBzcnRjBmFwcF9pZAo2NjI4NTY4Mzc5AAEe7tznjb2sAb2p8byGrJJiouNu8J0mv7pQkMT6r5-fYXmnmTDrO2bg4wv7WFQ_aem_RgftKElnJ_s-BCk0zsBM4g

Few other drugs have hit the market with the speed and ferocity of the GLP-1 weight loss medications. The rapid increase in users has led to an est...

24/12/2025

Wishing you all a very merry festive break and a very happy and healthy 2026.

01/12/2025

The new Lancet series pulls together data from over a hundred long-term studies, and the patterns it highlights are hard to ignore. Ultra processed foods disrupt the biological networks that keep us healthy.

The Series shows how UPFs have become dominant in diets across the globe, driven by powerful corporations and political strategies that prioritize profit over health. And it makes an important point, one I deeply agree with: education alone isn’t enough. We need coordinated policies that improve access to real, minimally processed foods and strengthen local food systems.

If we want to change the trajectory of chronic disease, we have to change the food environment that shapes our choices.

This is exactly what I explore in Food Fix, and why I believe this moment matters.

If you want to learn what it will take to rebuild a food system that truly supports human health, drop a YES below and I’ll DM you the link to preorder.

21/11/2025

Could the answer to the current allergy epidemic in our children be as simple as feeding them blueberries? A rigorously run infant RCT suggests that adding blueberries as one of the first solids may nudge immune balance in an anti-allergic direction and help allergy-type symptoms settle during the first year—while also shifting the gut microbiome in potentially favourable ways.

The first year of life is a critical window for establishing immune competence and preventing allergic diseases. Dietary exposures during this period can influence the induction of immune tolerance, epigenetic programming, and gut microbial succession.

In a double blind, randomised, placebo-controlled feeding trial in Denver, USA, exclusively breast-fed infants (n=61, start age 5–6 months) received freeze-dried blueberry powder (10 g/day) or an isocaloric, colour/flavour-matched placebo until 12 months of age.

The blueberry group started out with more respiratory/allergy-like symptoms at baseline yet showed a greater resolution over time vs placebo (trajectory p=0.05). Immune biomarkers: IL-13 (pro-allergic/Th2 response) fell significantly with blueberries (p=0.035); IL-10 (anti-inflammatory/regulatory) trended up (p=0.052). However, the changes in these cytokines could not directly explain symptom changes. However, specific gut microbiome changes at 12 months correlated with the cytokine changes, hinting at gut-immune crosstalk.

In a companion paper in the same cohort, blueberry introduction altered gut microbiota composition/diversity (trends toward higher alpha diversity; increases in short-chain fatty acid-associated genera such as Subdoligranulum/Butyricicoccus and reductions in potentially unfavourable organisms such as Escherichia/Streptococcus).

The findings align with broader evidence showing that diverse, fibre- and polyphenol-rich complementary diets plus early allergen introduction help shape the gut-immune axis toward tolerance.

For more information see: https://bit.ly/4i7mr2M
and
https://pubmed.ncbi.nlm.nih.gov/40944184/

13/11/2025

Jacqui and I have been planning a wonderful day for you all.
Sunday 7th December
The Open Practice, Basingstoke
10.00 am - 4.00 pm

* gentle yoga to stretch out and relax your body
* mindfulness meditation for calm and clarity
* a talk on foods you can eat to fight stress
* delicious lunch
* leave feeling restored and ready to take on the world from a more grounded and peaceful place

We still have a couple of spaces left.
email me to book: bex.yoga@gmail.com

http://rebeccajamesyoga.co.uk/
https://www.jacquimayes.co.uk/
https://www.theopen-practice.co.uk/

09/11/2025

A great day of learning yesterday at The British Network for Functional Medicine conference. Looking at Understanding The Human Threat System, Mast Cell Activation, Stealth Pathogens and Infections, Methylation & the Mind: How Epigenetic Switches Shape Mood, Focus, and Emotional Resilience.

06/11/2025

Our fabulous wellbeing retreat is happening at The Open Practice a month tomorrow. Why not join us for a day of self care, restorative yoga practice, mindfulness, a delicious nutritious lunch and I will be giving a talk on 'Foods That Fight Stress'. Places are limited and are going fast, so do get in touch at bex.yoga@gmail.com to book your place.