B12 Be Well

25/01/2026

25/01/2026

I went onto Maunjaro last year and lost 3 stone BUT one of the side effects I had was HAIR LOSS which really scared me. I offer Biotin (Vitamin B7) injections for hair and nails so started a 6 week treatment and what a difference!!!! This picture is my hair in December (my hubby kindly took the picture while I was face painting!!!!!!). The 2nd one I have done a comparison which shows a difference after about 5/6 weeks.

22/12/2025

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Treatment
While finding out you have a B12 deficiency can be both unsettling and worrying, it’s important to know that, correct and timely B12 treatment can mean reversal of all of your symptoms. You can rebuild that protective myelin sheath and live life feeling well again with the right frequency and the right kind of treatment for you.
There are different forms of B12 and different deliveries…
Hydroxocobalamin injections
Hydroxocobalamin injections are used to treat B12 deficiency by the NHS in the UK. This is a very stable form of B12 and is converted to methylcobalamin and adenosylcobalamin in the body.
In the UK, injectable B12 is only available on prescription. If B12 deficiency is caused by a malabsorption issue and not dietary lack, injections will be required for life. Once diagnosed, treatment in the UK is defined by NICE and BNF Guidance, however this guidance incorrectly assumes we are all the same with the same level of need. New Guidance is due to be discussed so hopefully this will be properly addressed.
NICE states that firstly a loading dose; intramuscular B12 injections of hydroxocobalamin should be given every other day for two weeks.
This frequency should continue for patients with neurological involvement, until all symptoms stop improving.
This should then be followed by lifelong maintenance doses of hydroxocobalamin at two-monthly intervals. But what about those without neurological symptoms? Well unfortunately, you are allowed a loading dose and then one injection every three months. Many cannot cope on the restricted ‘maintenance’ regimes and they are not based on clinical evidence, they came about as a result of cost saving exercises. The petition to make B12 injections available to buy from pharmacies in the UK continues.
Please note: There is no known toxicity of B12, it has been in safe use for over 60 years. B12 it is used in huge quantities as a treatment for cyanide poisoning.
Cyanocobalamin
Injectable cyanocobalamin is commonly used in the US and Canada and some European countries. This form converts to hydroxocobalamin and then to methylcobalamin and adenosylcobalamin in the body. It is a very stable form but is considered inferior to hydroxocobalamin and it can worsen Leber’s optic atrophy. It is advised that smokers do not use cyanocobalamin.
Oral cyanocobalamin is a supplement in tablet form. They are suitable only for the small number of people with proven dietary deficiency of vitamin B12. See this BMJ article for more info.
Please note: Those of you in the US should be able to access hydroxocobalamin via prescription from both CVS and Walgreens pharmacies.
Methylcobalamin & Adenosylcobalamin
Methylcobalamin is available in injection form in the UK from private doctors or available over the counter in the form of sublingual lozenges, capsules, sublingual sprays, nasal sprays and patches. It’s important to note that these supplements will not be effective treatment for everyone.
Adenosylcobalamin is another form of active B12 which can also be used in injection form but is more commonly used in sublingual lozenges, as liquid drops or in powder form.
Please note: we are all different and we may respond differently to the individual forms of B12. Some patients might require a combination of forms and quantity and frequency for optimal treatment.
Co-factors
Folate is a key co-factor to B12 and is very often low when B12 deficiency is found. Please see the folate page for more information. It is also wise to take a good vitamin B complex in addition to your B12 injection as all B vitamins need each other to work properly. Supplementing one in isolation can cause an imbalance in others.
B12info.com

26/11/2025

Some interesting reading:

🌿 𝗪𝗵𝗮𝘁 𝗛𝗮𝗽𝗽𝗲𝗻𝘀 𝗶𝗳 𝗬𝗼𝘂𝗿 𝗕𝟭𝟮 𝗗𝗲𝗳𝗶𝗰𝗶𝗲𝗻𝗰𝘆 𝗜𝘀 𝗟𝗲𝗳𝘁 𝗨𝗻𝘁𝗿𝗲𝗮𝘁𝗲𝗱?
Your red blood cells, nerves, and brain all depend on vitamin B12. But many people — especially vegans, those with gut issues, or adults over 50 — are running low and don’t even know it.
A simple blood test can reveal if you’re deficient. 𝗔𝗻𝗱 𝗶𝗳 𝘆𝗼𝘂 𝗶𝗴𝗻𝗼𝗿𝗲 𝗶𝘁… 𝘁𝗵𝗲 𝗿𝗲𝘀𝘂𝗹𝘁𝘀 𝗰𝗮𝗻 𝗮𝗳𝗳𝗲𝗰𝘁 𝘆𝗼𝘂𝗿 𝘄𝗵𝗼𝗹𝗲 𝗯𝗼𝗱𝘆 𝗮𝗻𝗱 𝗺𝗶𝗻𝗱.
⚠️ 𝗨𝗻𝘁𝗿𝗲𝗮𝘁𝗲𝗱 𝗕𝟭𝟮 𝗱𝗲𝗳𝗶𝗰𝗶𝗲𝗻𝗰𝘆 𝗰𝗮𝗻 𝗹𝗲𝗮𝗱 𝘁𝗼:
• 🩸 𝗔𝗻𝗲𝗺𝗶𝗮 — fatigue, pale skin, fast heartbeat, dizziness
• 🧠 𝗡𝗲𝗿𝘃𝗲 𝗱𝗮𝗺𝗮𝗴𝗲 — tingling, numbness, balance issues, weakness
• 💭 𝗕𝗿𝗮𝗶𝗻 & 𝗺𝗼𝗼𝗱 𝗰𝗵𝗮𝗻𝗴𝗲𝘀 — anxiety, depression, brain fog, memory loss
• ❤️ 𝗛𝗲𝗮𝗿𝘁 𝘀𝘁𝗿𝗮𝗶𝗻 — increased risk for heart attack or stroke
• 🦴 𝗕𝗼𝗻𝗲 𝗹𝗼𝘀𝘀 & 𝗳𝗲𝗿𝘁𝗶𝗹𝗶𝘁𝘆 𝗰𝗼𝗻𝗰𝗲𝗿𝗻𝘀 — weakened bones and hormonal changes
When your B12 stays low too long, some 𝗱𝗮𝗺𝗮𝗴𝗲 𝗺𝗮𝘆 𝗯𝗲𝗰𝗼𝗺𝗲 𝗽𝗲𝗿𝗺𝗮𝗻𝗲𝗻𝘁 — especially to nerves and the brain.

23/11/2025

www.bewellb12.co.uk

13/11/2025

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Mindset & Body Reset.

🌿 Did you know B12 deficiency can be the hidden root of mental health struggles?

It’s not just about “low energy.” Vitamin B12 plays a direct role in mood, cognition, and brain chemistry.

👉 Up to 30% of patients hospitalized for depression are deficient in B12.
👉 Case studies show even severe depression with catatonia can fully reverse when B12 is corrected. One woman who didn’t respond to medications went into remission after B12 therapy—and never relapsed.

⚠️ What causes deficiency?
• Diet low in animal protein
• Low stomach acid or gut absorption issues
• Autoimmune conditions
• Alcohol use
• Certain medications (like acid blockers & metformin)

✅ Optimal levels: We recommend aiming for >600 pg/mL—not just “within range.”

💡 Moral of the story: Don’t overlook your labs. B12 could be the missing piece of the puzzle.
Mood disorder with mixed, psychotic features due to vitamin b12 deficiency in an adolescent: case report.

Tufan AE, Bilici R, Usta G, Erdogan A. (2012) Child Adolesc Psychiatry Ment Health. 22;6(1) 25. doi: 10.1186/1753-2000-6-25.

Web URL: View this and related abstracts via PubMed here. Free full text of this article is available online.

Abstract:
Vitamin B12 is one of the essential vitamins affecting various systems of the body. Reports of psychiatric disorders due to its deficiency mostly focus on middle aged and elderly patients.

Here we report a case of vitamin B 12 deficiency in a 16-year old, male adolescent who presented with mixed mood disorder symptoms with psychotic features. Chief complaints were "irritability, regressive behavior, apathy, crying and truancy" which lasted for a year.

Premorbid personality was unremarkable with no substance use/exposure or infections. No stressors were present. The patient was not vegetarian. Past medical history and family history was normal.

Neurological examination revealed glossitis, ataxia, rigidity in both shoulders, cog-wheel rigidity in the left elbow, bilateral problems of coordination in cerebellar examination, reduced swinging of the arms and masked face. Romberg's sign was present. Laboratory evaluations were normal. Endoscopy and biopsy revealed atrophy of the gastric mucosa with Helicobacter Pylori colonization. Schilling test was suggestive of malabsorbtion.

He was diagnosed with Mood disorder with Mixed, Psychotic Features due to Vitamin B12 Deficiency and risperidone 0.5 mg/day and intramuscular vitamin B12 500 mcg/day were started along with referral for treatment of Helicobacter pylori.

A visit on the second week revealed no psychotic features. Romberg's sign was negative and cerebellar tests were normal. Extrapyramidal symptoms were reduced while Vitamin B12 levels were elevated. Risperidone was stopped and parenteral Vitamin B12 treatment was continued with monthly injections for 3 months.

Follow-up endoscopy and biopsy at the first month demonstrated eradication of H. pylori. He was followed monthly for another 6 months and psychiatric symptoms did not recur at the time of last evaluation.

Despite limitations, this case may underline the observation that mood disorders with psychotic features especially with accompanying extrapyramidal symptoms lacking a clear etiology may be rare manifestation of vitamin B12 and/or folate deficiency in children and adolescents and be potentially amenable to treatment.

12/10/2025

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When your doctor says you do not have pernicious anaemia because you are negative for intrinsic factor antibodies or that you cannot be deficient because your B12 is too high, you could show him/her this photo. Every area highlighted in blue could be the reason why you cannot absorb B12.
INTRINSIC FACTOR ANTIBODIES
Also known as: IFAb
Pernicious Anaemia is a clinical manifestation of autoimmune gastritis and is associated with the presence of intrinsic factor antibodies. There are two types of intrinsic factor antibody: type 1 binds to the vitamin B12 binding site and type 2 hinders the binding site by binding to structures nearby. Intrinsic factor antibodies are only performed in patients who are positive for gastric parietal cell antibodies.
New Guidelines for the diagnosis and treatment of cobalamin and folate disorders
All patients with anaemia, neuropathy or glossitis, and suspected of having pernicious anaemia, should be tested for anti-IFAB regardless of cobalamin levels (Grade 1A).
Patients found to have a low serum cobalamin level in the absence of anaemia and who do not have food malabsorption or other causes of deficiency, should be tested for IFAB to clarify whether they have an early/latent presentation of pernicious anaemia (Grade 2A).
Anti-GPC antibody testing for diagnosing pernicious anaemia is not recommended (Grade 1A).
GASTRIC PARIETAL CELL ANTIBODY
Also known as: GPC
Gastric parietal cell antibodies (GPC) are directed against a parietal cell enzyme, the H+K+ATPase. The auto-antibody is found at high frequency in association with autoimmune gastritis and a proportion of these patients will progress to develop pernicious anaemia.
Gastric parietal cell antibodies are present in over 90% of patients with pernicious anaemia (Highly sensitive, but not specific).
GPC antibodies should be looked for in:
Vitamin B12 deficiency
Macrocytic anaemia
Subacute combined degeneration of the cord
Individuals with other autoimmune disease i.e. thyroid disease
https://www.cmaj.ca/content/171/3/251

30/07/2025

Give your body and mind a boost. Vitamin B12 injections are amazing. Please have a look at my website for more information.
To book an appointment please use website or Tel/Whatsapp me on 07368 397842

Be Well B12 provides vitamin B12, D, and biotin injections to boost energy, support immunity, and promote overall wellbeing, beauty, and vitality.

27/06/2025

My new website.

Be Well B12 provides vitamin B12, D, and biotin injections to boost energy, support immunity, and promote overall wellbeing, beauty, and vitality.

15/06/2025

Please contact me on Tel/WhatsApp 0736 839 7842 to book an appointment or if you have any questions. Home visits available at no extra cost. Appointments take about 15 minutes and cost £20.

22/04/2025

Please contact me for more information or to make an appointment.
Free home visits can be arranged
Tel/WhatsApp : 07368397842
B12 injections are £20.