29/11/2025
Medicinal Mushroom Series: Maitake
Grifola frondosa: also known by its Japanese name Maitake, English name Hen of the Woods, and Chinese name Hui Shu Hua, is a polypore mushroom that is sought after for its delicious flavour and texture, as well as its health benefits. It is revered in Asia (particularly Japan) for its healing effects, in particular its nutrient content and immune-activating, blood-sugar regulating, and antitumour properties.
Maitake grows in clusters at the base of trees, particularly oaks. It is identified by its large, cauliflower-like rosette of tan to olive-coloured fronds and pale cream pores. It has a rich, earthy scent and is prized for its nutritional and potential health benefits, including its use in supplements and skin care products due to its high content of vitamins, minerals, and antioxidants.
The major well-documented active components in Maitake are the polysaccharides (beta-glucan, heteropolysaccharide, and proteoglycan fractions) that have been shown to have potent immunomodulatory action. These compounds modulate the immune system by enhancing the activity of white blood cells and potentially aiding the body’s cellular defence mechanisms.
Other benefits include:
- Blood Sugar Management: Bioactive compounds in Maitake may help support healthy blood glucose levels by improving insulin sensitivity and reducing glucose absorption.
- Cardiovascular Health and Cholesterol Management: Maitake’s components can contribute to heart health by helping to maintain healthy cholesterol levels and supporting healthy arterial function.
- Antioxidant Properties: Maitake is rich in antioxidants like ergothioneine, which help protect the body from environmental stressors and cell damage.
- Anti-inflammatory Effects: Extracts from Maitake have been found to possess anti-inflammatory properties.
- Bone Health: Maitake is a good source of vitamin D, which is essential for strong bones.
- Weight Management: Some research suggests potential benefits in managing weight and reducing fat accumulation.
Cautions:
- Blood Pressure Medications: Maitake might lower blood pressure. Taking it with antihypertensive drugs might cause blood pressure to drop too low. Monitor your blood pressure closely if combining them.
- Diabetes Medications: Maitake may lower blood sugar levels. Taking it with antidiabetes drugs might cause blood sugar to drop too low (hypoglycemia), requiring close monitoring and potential adjustment of medication by a healthcare provider.
- Blood Thinners: Maitake might increase the effects of blood-thinning medications like warfarin (Coumadin), potentially raising the risk of bleeding. A healthcare provider may need to monitor you more often and adjust the warfarin dose.
- Surgery: Due to its potential effects on blood sugar and blood pressure, it's recommended to stop using maitake mushroom at least two weeks before a scheduled surgery.
- Immunosuppressants: Maitake might interfere with immunosuppressant medications.
References:
Hobbs, C. (2020). Medicinal Mushrooms: The Essential Guide. Storey Publishing, USA.
Powell, M. (2014). Medicinal Mushrooms: A Clinical Guide. Bamboo Publishing, UK.