17/12/2025
Thanks to poor-quality, outdated research on old formulations of HRT, many people believe that higher doses of HRT = higher risks. This simply isn’t true.
For example, a Newson Health study revealed that up to 1 in 4 women may require higher doses of estradiol to achieve optimal blood levels for symptom relief and to protect future health - because absorption through the skin differs between individuals*.
Because every woman absorbs differently, tailoring HRT doses and formulation to an individual is key. There should never be a one-size-fits-all approach to HRT.
If your symptoms aren’t improving, it may be time to review your dose or formulation with your clinician.
Book in with one of our experts for personalised support.
*Glynne S., Reisel D., Kamal A., Neville A., McColl L., Lewis R., Newson L. (2025),‘The range and variation in serum estradiol concentration in perimenopausal and postmenopausal women treated with transdermal estradiol in a real-world setting: a cross-sectional study’, Menopause, 32(2) pp103-111. doi: 10.1097/GME.0000000000002459