19/02/2026
Case study — 43 year-old, heavy bleeding and history of polyps.
Red flags were ruled out, but she still didn’t feel right — so we tested deeper.
Symptoms
* Heavy menstrual bleeding
* History of polyps (red flags ruled out)
* Fatigue
* Hair loss
* Bloating, gas
* Alternating diarrhoea/constipation
* General feeling “not right”
We ran a DUTCH hormone test, thyroid blood test and comprehensive gut testing.
Hormones showed:
• Cortisol at the higher end but sluggish clearance off the cortisol — so her adrenals and liver need support.
• Progesterone below range — she has a Mirena coil, which can suppress natural progesterone production (but not for all)
• Oestrogen higher relative to progesterone — creating oestrogen dominance
Yes, perimenopause causes fluctuations — but this pattern needs clinical correlation with symptoms.
Detox pathways were mostly in range, but the 16-OH pathway was lower. vaginal cream maybe helpful for dryness
Androgens were mixed largely in range
Biotin was low — which may explain her hair thinning plus the thyroid labs
Thyroid - subclinical hypothyroid & hashimotos
Now the gut piece…
She had bloating, gas, loss stools or constipation and fatigue.
Testing showed bacterial overgrowth, two parasites, gut inflammation, low stomach acid, reduced gut immune markers, and poor phase 3 detox — meaning hormones may be recirculating instead of clearing.
So this isn’t just hormones. It’s hormone–gut–stress axis dysfunction.
Plan?
Start with hormone and adrenal support first.
Then move into a structured gut protocol.
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