Dr Shambo Samrat Samajdar MD DM- Clinical Pharmacology

Dr Shambo Samrat Samajdar MD DM- Clinical Pharmacology MBBS(R G Kar Medical College and Hospital), MD, DM (Clinical Pharmacology), DAAI, PG Dip Endo & Diab

Mon Wed Fri-7 pm
Tues Thurs Sat - 6 pm
Diabetes & Allergy-Asthma Therapeutics Specialty Clinic
Sanito engineering factory complex.beside balaka apartment. Near L G Showroom and MORE at jardabagan
F/F 3 Hatiara Road, Baguiati

Call in this number +91 86177 56992 for appointment and direction

🔬 Scientific Community Insight | Rational Prescribing in the ElderlyThe growing burden of polypharmacy and inappropriate...
28/03/2026

🔬 Scientific Community Insight | Rational Prescribing in the Elderly

The growing burden of polypharmacy and inappropriate prescribing in elderly patients is a silent but significant threat to patient safety.

🧠 Key Messages

1. Aging alters drug response → reduced clearance, increased sensitivity, higher risk of adverse effects
2. Polypharmacy is highly prevalent → majority of elderly patients are on ≥5 drugs
3. Inappropriate prescribing is common → overuse, misuse, and duplication of therapies coexist
4. High-risk drugs frequently used → PPIs, benzodiazepines, NSAIDs, anticholinergics
5. Under-treatment also exists → evidence-based therapies are often missed
6. Drug–drug and drug–disease interactions are under-recognized

⚠️ Clinical Reality

This is not just a prescribing issue—
it reflects fragmented care, protocol-driven medicine, and lack of therapeutic individualization.

👨‍⚕️ Role of Clinical Pharmacologist — The Need of the Hour

1. Experts in rational pharmacotherapy and deprescribing
2. Essential for medication review, risk–benefit assessment, and optimization
3. Bridge the gap between guidelines and real-world patient complexity

🌿 Take-Home Message

Better outcomes in elderly care will not come from more drugs—
but from better, safer, and more rational use of drugs.

👉 Clinical Pharmacology must be integrated into routine patient care.

Well done Dr Rupak Chatterjee for leading this excellent work.

Link to read: https://journals.lww.com/jiag/fulltext/2026/01000/potentially_inappropriate_prescribing_in_the.10.aspx

Delivered my talk at ISLET 2026, Bangalore, on an intriguing and highly relevant theme — “Ancient Indian Medicine in the...
25/03/2026

Delivered my talk at ISLET 2026, Bangalore, on an intriguing and highly relevant theme — “Ancient Indian Medicine in the Modern Era: Myth or Reality? Implications for Diabetes and Cardiometabolic Disease.”

The discussion centered on a critical question in today’s clinical practice: Are we missing something fundamental in how we approach chronic diseases like diabetes?

We explored how modern medicine, despite its remarkable advances, continues to struggle with long-term adherence, behavioral challenges, and the psychosocial burden of chronic disease. The concept of Cardiovascular–Kidney–Metabolic (CKM) syndrome highlights that diabetes is not merely a disorder of glucose, but a complex multisystem condition involving inflammation, neurohormonal activation, and lifestyle determinants.

Interestingly, ancient Indian medicine (Ayurveda) had already proposed a systems-based, holistic model of health thousands of years ago—integrating body, mind, environment, and consciousness. Its structured clinical reasoning (Hetu–Linga–Aushadha) parallels modern medical frameworks of etiology, diagnosis, and therapy.

Key highlights from the talk:
• Emphasis on **lifestyle medicine** — Ahara (diet), Vihara (lifestyle), and Ritucharya (seasonal adaptation)
• Recognition of **stress biology (HPA axis)** as a major driver of insulin resistance and inflammation
• Emerging evidence supporting **yoga and mind–body interventions** in improving glycemic control, inflammatory markers, and quality of life
• The importance of **behavioral and psychological resilience** in long-term diabetes care
• A forward-looking **integrative model**: *Biology + Behavior + Meaning → Sustainable metabolic health*

The key takeaway:
**Ancient Indian medicine is neither a myth nor a replacement for modern science—it is a valuable knowledge reservoir that can complement contemporary care, especially in chronic metabolic diseases.**

When medicine treats glucose alone, it treats a number.
When it treats the whole human being—**body, mind, and spirit—it truly treats diabetes.**

Thank you Drsreenivasa Murthy sir for giving me this opportunity to me for learning and re-learning this interesting topic.
My sincere pronaam to Shashank R Joshi sir who had taught me this concept.

Once again Kudos to you sir “The LSM” for organising this wonderful academic feast with synergistic fixed dose combination of science, technology, hospitality, food and special personal “LSM” touch in every little aspect.
Pronaam and Big Thank You 🙏

A Few moments from IPSWBCON & Eastern Zonal Academia Big Congratulations to Medical College Kolkata for organising this ...
18/03/2026

A Few moments from IPSWBCON & Eastern Zonal Academia

Big Congratulations to Medical College Kolkata for organising this efficient way.

Best of luck to Dr Payodhi Dhar for upcoming National Conference of IPS.

Eagerly waiting to join this great academic conclave organised by Prof. L. Sreenivasa MurthyPrestigious conference with ...
16/03/2026

Eagerly waiting to join this great academic conclave organised by Prof. L. Sreenivasa Murthy

Prestigious conference with fantastic scientific program and extraordinary faculties across India - https://isletacademy.com/scientific-agenda

Thank you Drsreenivasa Murthy sir giving me the opportunity.

Waiting for this weekend academic engagement
Registration Link: https://isletacademy.com/

A Few Moments in Varanasi — the sacred land associated with Pujya Swami Karpatri Ji Maharaj.In this timeless city, one w...
14/03/2026

A Few Moments in Varanasi — the sacred land associated with Pujya Swami Karpatri Ji Maharaj.

In this timeless city, one word from Pujya Swami ji Maharaj quietly echoes through every ghat, every temple bell, every flowing wave of the Ganga — Sanyam (self-discipline). Perhaps that is why our traditions remind us that Sanyam is essential both for Swasthya (health) and Sadhana (spiritual practice). The same restraint that steadies the mind also protects the body.

Grateful to Dr. Ashutosh Mishra for the warm invitation to speak in 15th National Conference “Cardiabcon” that made this visit possible.

In Kashi, you don’t merely visit temples — you quietly begin to witness Shiva everywhere.

In the river.
In the silence.
In the ancient rhythm of this eternal city.

Some journeys are planned.
Some are blessings.

Shiva Kripa.
Guru Kripa.
Jana Kripa.

Har Har Mahadev. 🙏

Interesting Topic to Discuss in the Ancient most city in this universe - Varanasi Har Har Mahadev 🙏
13/03/2026

Interesting Topic to Discuss in the Ancient most city in this universe - Varanasi

Har Har Mahadev 🙏

Scientific Session Contribution | API West Bengal CME SeriesHappy to deliver two academic sessions during the Workshop o...
11/03/2026

Scientific Session Contribution | API West Bengal CME Series

Happy to deliver two academic sessions during the Workshop on Thesis Preparation & Research Methodology, organised by the Physician Research Foundation (PRF), West Bengal, under the aegis of the Association of Physicians of India (API), West Bengal Chapter.

My sessions focused on strengthening the fundamentals of clinical research thinking among postgraduate residents and young physicians.

In the first lecture, “Introduction to Clinical Research: From Ward Problems to Answerable Questions,” the discussion centered on how everyday clinical uncertainties encountered at the bedside can be transformed into structured research questions. The session highlighted the principles of evidence-based healthcare, the importance of well-defined research questions, and common pitfalls in resident thesis projects, such as vague study questions, poorly planned data collection, and difficulty translating results into meaningful clinical insights.

The second lecture, “Research Problem and Objectives: Turning Clinical Uncertainty into a Study,” focused on the critical step of converting a broad clinical topic into a precise research problem. Key concepts included identifying knowledge gaps from clinical practice, structuring research questions using frameworks such as PICO (Patient–Intervention–Comparison–Outcome), and developing clear, measurable research objectives using the SMART principle. Emphasis was placed on designing focused studies that answer a few important clinical questions well rather than many questions superficially.

The central message across both sessions was that high-quality clinical research begins with curiosity at the bedside, but succeeds only when that curiosity is translated into a well-defined research question and carefully planned study design.

It was a pleasure to interact with enthusiastic residents and colleagues committed to building a stronger culture of physician-led research and evidence-based clinical practice.
Special Thanks to Prof Jyotirmoy Pal, Prof Partha Sarkar, Prof Uttam Paul and Prof Nandini Chatterjee.
Dr Rupak Chatterjee and Dr Partha Dutta Cphhr India CPHHR India had done a great job too.

📢 New Publication in JAPIWe are pleased to share the publication of our research article:“A Study on Prevalence of Malar...
10/03/2026

📢 New Publication in JAPI

We are pleased to share the publication of our research article:

“A Study on Prevalence of Malarial Retinopathy among Malaria Cases and to Determine Its Presence as a Marker of Severe Malaria: Observations from Eastern India” in the Journal of the Association of Physicians of India (JAPI).

Malaria continues to remain a major public health challenge in tropical countries. Our study explored the prevalence and clinical significance of malarial retinopathy, a constellation of retinal findings including retinal whitening, vascular changes, hemorrhages, and papilledema, which reflect microvascular pathology in severe malaria.

Conducted at the School of Tropical Medicine, Kolkata, in collaboration with the Regional Institute of Ophthalmology, this observational study included 71 malaria cases. The findings demonstrated that malarial retinopathy was present in 75% of severe malaria cases but only 3.4% of uncomplicated cases, suggesting a strong association between retinal changes and disease severity. The study also showed that malarial retinopathy had high specificity (96.6%) and good sensitivity (75%) as a clinical marker of severe malaria, highlighting the potential role of bedside direct ophthalmoscopy as a simple, noninvasive diagnostic tool for early severity assessment.

These findings emphasize the importance of retinal examination in malaria patients, as the retina—sharing embryological and vascular similarities with the brain—can serve as a window to detect microvascular changes associated with severe systemic disease.

We extend our heartfelt appreciation to Lead Investigator Dr. Rupak Chatterjee for his outstanding leadership and scientific vision in conceptualizing and executing this study. We also congratulate and thank all our dedicated co-investigators and collaborators whose collective efforts made this research possible.

Link to read: https://www.japi.org/article/japi-74-3-62

We are happy to share the publication of our article:“Reviving the Spirit of Physician-led Innovation: The Launch of the...
09/03/2026

We are happy to share the publication of our article:
“Reviving the Spirit of Physician-led Innovation: The Launch of the Physician Research Foundation West Bengal Chapter” in the Bengal Physician Journal (2026).

The article highlights the vision behind establishing the Physician Research Foundation (PRF), West Bengal Chapter, under the aegis of the Association of Physicians of India (API), West Bengal. The initiative aims to strengthen physician-led research, academic collaboration, and research capacity among practicing clinicians, enabling clinically relevant and indigenous scientific contributions.

By integrating research within routine clinical practice and encouraging mentorship, education, and collaborative studies, PRF aspires to cultivate a vibrant ecosystem of clinician-scientists committed to advancing patient-centered healthcare.

This milestone reflects the collective efforts of the API West Bengal community and the enduring legacy of physician-driven scientific inquiry.

Special acknowledgement to Prof. (Dr.) Jyotirmoy Pal, whose visionary leadership and academic foresight played a pivotal role in conceptualizing and establishing this initiative under API West Bengal.

Link to read our letter to editor: https://www.apibpj.com/abstractArticleContentBrowse/BPJ/63/13/1/44313/abstractArticle/Article

Happy to contribute an awareness message on World Obesity Day, published in The Indian Express yesterday. The article hi...
07/03/2026

Happy to contribute an awareness message on World Obesity Day, published in The Indian Express yesterday. The article highlights an often-ignored reality in clinical practice — obesity and depression frequently travel together, linked not only by behavior but also by shared biological pathways involving hormones, inflammation, and metabolic signaling.
It also emphasizes the growing need for prescription reconciliation and therapeutic optimisation in obesity care. Many commonly used medicines can quietly influence body weight or mood, and a structured Clinical Pharmacological Reconciliation Review and Feedback (CPRRF) approach through a dedicated Clinical Pharmacology OPD can help personalise therapy, reduce unintended medication effects, and improve long-term outcomes.
Because managing obesity is not merely about calories — it is about chemistry, psychology, and thoughtful pharmacology working together.

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F/F 3 Hatiara Road Baguiati
Kolkata

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Monday 7pm - 9pm
Tuesday 7pm - 9pm
Wednesday 7pm - 9pm
Thursday 7pm - 9pm
Friday 7pm - 9pm
Saturday 7pm - 9pm

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