Sanitech Engineers

Sanitech Engineers Separation and Purification Technology Experts. Sanitech - the future of engineering excellence

Are your plant extracts losing value before they become a pill?Poor clarification, harsh concentration and nonselective ...
31/10/2025

Are your plant extracts losing value before they become a pill?
Poor clarification, harsh concentration and nonselective polishing strip marker compounds, raise solvent and water costs, and create organoleptic and stability issues.

A practical plant-to-pill purification train fixes this: characterise feed, use gentle staged clarification, apply selective adsorption or preparative chromatography, and use low-temperature concentration such as TFF. For extraction, consider greener supercritical fluid extraction with CO2 as an alternative to solvent extraction to reduce solvent use and protect marker integrity. Diafiltration and formulation conditioning lock in stability for downstream processing.

Representative pilots show markedly improved marker retention, lower solvent consumption, and faster campaigns when feed-aware purification and gentle concentration are applied. We can include a bench SFE feasibility screen within the pilot to quantify solvent savings, selectivity, and marker recovery for your material.

Learn More: https://sanitech-engineers.com/industries/nutraceuticals/

Get in touch:

📧: info@sanitech-engineers.com

🌐: www.sanitech-engineers.com

📞 +91-22-6907-5151



Note: "Recovery rates and processing improvements are representative of typical applications and will vary based on molecule type, starting material quality, target purity specifications, buffer systems, and operating conditions. Individual results require validation through process development with your specific protein or peptide."

The last meters of your purification train decide vaccine release. Fragile viral antigens tolerate poor handoffs badly: ...
28/10/2025

The last meters of your purification train decide vaccine release. Fragile viral antigens tolerate poor handoffs badly: high shear, warm holds and aggressive polishing fragment epitopes and trigger QC holds. Precision low-shear workflows combine staged clarification, temperature-controlled TFF and mild polishing to preserve potency, reduce aggregation and cut release time. Representative pilots show markedly improved potency retention and fewer QC holds. Book a free assessment to map potency loss, quantify program impact and get a pilot-ready ROI sketch.

Get in touch:

📧: info@sanitech-engineers.com

🌐: www.sanitech-engineers.com

📞 +91-22-6907-5151



Note: "Recovery rates and processing improvements are representative of typical applications and will vary based on molecule type, starting material quality, target purity specifications, buffer systems, and operating conditions. Individual results require validation through process development with your specific protein or peptide."

The last 1% that decides release timelinesTrace ionic contaminants are the silent bottleneck in many API campaigns. They...
06/10/2025

The last 1% that decides release timelines

Trace ionic contaminants are the silent bottleneck in many API campaigns. They pass through capture and intermediate clean-up steps, they confuse assays, and they trigger QC holds that delay release by days or weeks. If you are seeing unexpected reworks, extra polishing passes, or ppm-level failures, the problem is not sloppy analytics, it is the final polish. Ion exchange, applied as a targeted polishing step, is the practical fix.

What we do, in plain terms:

we place a tuned ion exchange column after your main purification and conditioning steps, we control pH and conductivity to an operational window that favors your API, and we run a programmed salt gradient to elute impurities separately from the product. The result: charged traces and counter-ions are removed to regulatory targets, your sterile filter sees a clean feed, and QC waits collapse.

Why this matters to your bottom line:

• Faster approvals, faster shipments, more predictable batch timing: less time spent on rework and retesting.
• Higher effective yield: keep more product in the finished batch, reduce cost per gram.
• Lower consumables spend: fewer polishing cycles, longer resin life, less buffer used.
• Cleaner submissions: tighter impurity profiles make regulatory reviews smoother.

Get in touch:

📧: info@sanitech-engineers.com

🌐: www.sanitech-engineers.com

📞 +91-22-6907-5151



Note: "Recovery rates and processing improvements are representative of typical applications and will vary based on molecule type, starting material quality, target purity specifications, buffer systems, and operating conditions. Individual results require validation through process development with your specific protein or peptide."

Insulin yield suffers when handoffs are not engineered. Start with capture chromatography, condition the eluent, then ap...
29/09/2025

Insulin yield suffers when handoffs are not engineered. Start with capture chromatography, condition the eluent, then apply low-shear TFF with controlled TMP and temperature. Typical pilot gains include +20–30% recovery and 20–30% buffer savings.

Get in touch:

📧: info@sanitech-engineers.com

🌐: www.sanitech-engineers.com

📞 +91-22-6907-5151



Note: "Recovery rates and processing improvements are representative of typical applications and will vary based on molecule type, starting material quality, target purity specifications, buffer systems, and operating conditions. Individual results require validation through process development with your specific protein or peptide."

While competitors lose 48% of their antigens, what if you could recover >85%+? The difference is precision. Sanitech's m...
22/09/2025

While competitors lose 48% of their antigens, what if you could recover >85%+? The difference is precision.

Sanitech's membrane strategies preserve what matters: immunogenic structure, epitope integrity, and potency consistency.

Our 3-stage approach: gentle concentration (TFF) → selective clarification → endotoxin control. No shear damage. No false QC failures. No batch-to-batch variation.

Competitive edge achieved: One customer reduced cycle times from 18 to 12 days while improving QC pass rates from 70% to 97%.

Ready to outperform your competition?

Let's map your path to 87%+ recovery.

Get in touch:

📧: info@sanitech-engineers.com

🌐: www.sanitech-engineers.com

📞 +91-22-6907-5151

vaccine



Note: "QC pass rates and recovery percentages are based on representative case studies and may vary significantly depending on antigen type, bacterial strain, fermentation conditions, endotoxin levels, and downstream requirements. Process optimization and validation trials are essential to determine achievable performance for your specific application."

While your competitors struggle with 70% recovery rates, what if you could achieve > 80%+?The difference is integration....
08/09/2025

While your competitors struggle with 70% recovery rates, what if you could achieve > 80%+?

The difference is integration. Sanitech pairs membrane concentration with precision chromatography in one seamless skid - eliminating transfers, reducing contamination, and maximizing yield.

The competitive advantage: Faster cycles, lower costs, higher quality, easier validation.

Real customer: Peptide manufacturer went from 14-day cycles to 8-day cycles while improving recovery from 65% to 85%.

Ready to outpace your competition? Let's discuss your pathway to maximum recovery.

Get in touch:

📧: info@sanitech-engineers.com

🌐: www.sanitech-engineers.com

📞 +91-22-6907-5151



Note: "Recovery rates and processing improvements are representative of typical applications and will vary based on molecule type, starting material quality, target purity specifications, buffer systems, and operating conditions. Individual results require validation through process development with your specific protein or peptide."

Downstream is where process economics meets product quality. Fouling, yield loss during concentration, long buffer prep,...
03/09/2025

Downstream is where process economics meets product quality. Fouling, yield loss during concentration, long buffer prep, scale-up surprises and validation overhead are common, but solvable.

Our approach: early clarification with microfiltration, low-shear TFF with temperature and pressure control, inline buffer strategies plus automated buffer management, pilot validation, and pre-engineered skids with digital traceability.

Modern downstream success depends on predictive systems, continuous monitoring, and flexible automation that adapts to your specific molecule requirements.

Do you want to update your downstream process?

Get in touch:

📧: info@sanitech-engineers.com

🌐: www.sanitech-engineers.com

📞 +91-22-6907-5151

Why are your chromatography columns fouling so quickly?The answer lies upstream. Traditional clarification methods leave...
26/08/2025

Why are your chromatography columns fouling so quickly?

The answer lies upstream. Traditional clarification methods leave microscopic debris that slowly kills expensive resins. Sanitech's MF + TFF integration catches what centrifugation misses - protecting your downstream assets from day one.

The result? Our customers see column lifetimes extend 150%, buffer costs drop 35%, and batch reproducibility improve to

Join Sanitech Engineers at India’s Premier Pharma Machinery Expo.Let’s talk about purification processes and systems tha...
14/08/2025

Join Sanitech Engineers at India’s Premier Pharma Machinery Expo.
Let’s talk about purification processes and systems that perform — from lab scale to commercial.

Date: 18th, 19th & 20th September 2025
Hall No. 7, Booth D63
Venue: HITEX Exhibition Centre, Hyderabad

🌐 www.sanitechengineers.in
✉️ info@sanitechengineers.in
📞 Bhargav Rao – 8977439696 (For Scheduling Meeting)

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