https://www.sanitech-engineers.com/

Sanitech Engineers, W-199-E, MIDC Khairne, Thane Belapur Road, NAVI MUMBAI (2026)

15/12/2025

Sample load is not just an input number.
It’s the first decision that controls everything downstream.

Overload a column and you damage packing, distort flow paths, widen peaks, and shorten resin life.

Underload it and you waste capacity, time, and money.

When loading is optimized, everything improves at once:

✔ sharper separation
✔ higher recovery
✔ stable pressure behavior
✔ faster cycle times
✔ longer column life
✔ predictable scale-up

At Sanitech Engineers, we design preparative chromatography systems that actively control load in real time, managing flow, pressure, injection volume, and protection limits so every run uses the column’s true working capacity.

Learn More: https://sanitech-engineers.com/products/preparative-chromatography-systems/

Get In Touch:
📧: info@sanitech-engineers.com
🌐: www.sanitech-engineers.com
📞 +91-22-6907-5151

$Manual fraction collection creates timing errors that directly reduce yield.Automated fraction control fixes this by usi...$

10/12/2025

Manual fraction collection creates timing errors that directly reduce yield.

Automated fraction control fixes this by using UV slopes, conductivity shifts, and volume logic to define exact cutpoints, no early switching, no tail mixing, no over-collection.

Sanitech Engineers’ PD chromatography systems integrate multi-detector fraction logic for consistent purity and repeatable recovery across batches.

Learn More: https://sanitech-engineers.com/products/preparative-chromatography-systems/

Get In Touch:
📧: info@sanitech-engineers.com
🌐: www.sanitech-engineers.com
📞 +91-22-6907-5151

08/12/2025

Peptide chromatography is sensitive to flow, pH, packing and resin health, which is why tailing, bed collapse and pressure spikes are so common.

These 7 diagnostics help you isolate the exact failure point so you can correct the issue before it damages resin performance or batch quality.

Sanitech systems engineer every run with stable LRV, precise pH control, robust packing and real-time pressure monitoring to keep your peptide purification smooth and predictable.

Learn More: https://sanitech-engineers.com/products/preparative-chromatography-systems/

Get In Touch:

📧: info@sanitech-engineers.com

🌐: www.sanitech-engineers.com

📞 +91-22-6907-5151

02/12/2025

Audits don’t fail because chromatography performs poorly, they fail when PQ sampling, traceability, and acceptance criteria aren’t airtight.

This carousel breaks down the 7 steps Sanitech uses to make your chromatography inspection-ready by design.

From locked sampling logic to ALCOA+ data integrity and structured archival, every step reduces audit risk and boosts process reliability.

Strong runs. Stronger documentation. Zero surprises during inspections.

Learn More: https://sanitech-engineers.com/products/preparative-chromatography-systems/

Get In Touch:
📧: info@sanitech-engineers.com
🌐: www.sanitech-engineers.com
📞 +91-22-6907-5151

11/11/2025

Are you stripping flavor when you clarify?

Many teams discover the hard way that the wrong filter order or too-high flux removes the macromolecules that carry aroma and mouthfeel.

That costs volume, raises filter and cleaning bills, and sometimes leads to cloudy or off-flavor lots.

The fix is practical and low-risk: start coarse, go fine, and match the final polish to your objective. Control flux, TMP and temperature, and add guard layers to cut fouling.

Short pilots typically show measurable yield gains and lower filter spend.

Book a free clarification audit and a short pilot to validate pore sequencing on your product.

Learn More: https://sanitech-engineers.com/industries/foodandbeverages/

Get In Touch:

📧: info@sanitech-engineers.com

🌐: www.sanitech-engineers.com

📞 +91-22-6907-5151

10/11/2025

Is your membrane choice costing product function?

Many ingredient teams discover that a generic membrane steals active ingredients, increases cleaning cycles, and forces reformulation.

The right membrane recipe keeps desired components, reduces fouling, and lowers operating cost.

Our approach is practical: characterise the feed, pre-treat to remove foulants, then select a membrane and module architecture that preserves functionality.

We validate with quick bench screens and short pilots, delivering a pilot report, CIP recipe, and an ROI sketch.

Learn More: https://sanitech-engineers.com/industries/biopharmaceutical/

Get In Touch:

📧: info@sanitech-engineers.com

🌐: www.sanitech-engineers.com

📞 +91-22-6907-5151

Note: "Recovery rates and processing improvements are representative of typical applications and will vary based on molecule type, starting material quality, target purity specifications, buffer systems, and operating conditions. Individual results require validation through process development with your specific protein or peptide."

06/11/2025

Is purification killing your vitamins and enzymes? Heat, shear and pH swings during concentration and polishing commonly reduce
activity by 10–50% and cause rework in 3–12% of campaigns.

Those losses increase OPEX through extra stabilisers, analytics and delayed releases, and they shrink your effective yield per batch.

Protect activity with an activity-first train: feed characterisation, low-shear clarification, low-temperature TFF with tight TMP and flux control, diafiltration into stabilising buffers and mild polishing resins.

Learn More: https://sanitech-engineers.com/industries/biopharmaceutical/

Get In Touch:

📧: info@sanitech-engineers.com

🌐: www.sanitech-engineers.com

📞 +91-22-6907-5151

Note: "Recovery rates and processing improvements are representative of typical applications and will vary based on molecule type, starting material quality, target purity specifications, buffer systems, and operating conditions. Individual results require validation through process development with your specific protein or peptide."

31/10/2025

Are your plant extracts losing value before they become a pill?
Poor clarification, harsh concentration and nonselective polishing strip marker compounds, raise solvent and water costs, and create organoleptic and stability issues.

A practical plant-to-pill purification train fixes this: characterise feed, use gentle staged clarification, apply selective adsorption or preparative chromatography, and use low-temperature concentration such as TFF. For extraction, consider greener supercritical fluid extraction with CO2 as an alternative to solvent extraction to reduce solvent use and protect marker integrity. Diafiltration and formulation conditioning lock in stability for downstream processing.

Representative pilots show markedly improved marker retention, lower solvent consumption, and faster campaigns when feed-aware purification and gentle concentration are applied. We can include a bench SFE feasibility screen within the pilot to quantify solvent savings, selectivity, and marker recovery for your material.

Learn More: https://sanitech-engineers.com/industries/nutraceuticals/

Get in touch:

📧: info@sanitech-engineers.com

🌐: www.sanitech-engineers.com

📞 +91-22-6907-5151

Note: "Recovery rates and processing improvements are representative of typical applications and will vary based on molecule type, starting material quality, target purity specifications, buffer systems, and operating conditions. Individual results require validation through process development with your specific protein or peptide."

28/10/2025

The last meters of your purification train decide vaccine release. Fragile viral antigens tolerate poor handoffs badly: high shear, warm holds and aggressive polishing fragment epitopes and trigger QC holds. Precision low-shear workflows combine staged clarification, temperature-controlled TFF and mild polishing to preserve potency, reduce aggregation and cut release time. Representative pilots show markedly improved potency retention and fewer QC holds. Book a free assessment to map potency loss, quantify program impact and get a pilot-ready ROI sketch.

Get in touch:

📧: info@sanitech-engineers.com

🌐: www.sanitech-engineers.com

📞 +91-22-6907-5151

Note: "Recovery rates and processing improvements are representative of typical applications and will vary based on molecule type, starting material quality, target purity specifications, buffer systems, and operating conditions. Individual results require validation through process development with your specific protein or peptide."

18/10/2025

Let this Diwali be a celebration of purity, reflection, and light that leads forward.

Get in touch:
📧: info@sanitech-engineers.com
🌐: www.sanitech-engineers.com
📞 +91-22-6907-5151

06/10/2025

The last 1% that decides release timelines

Trace ionic contaminants are the silent bottleneck in many API campaigns. They pass through capture and intermediate clean-up steps, they confuse assays, and they trigger QC holds that delay release by days or weeks. If you are seeing unexpected reworks, extra polishing passes, or ppm-level failures, the problem is not sloppy analytics, it is the final polish. Ion exchange, applied as a targeted polishing step, is the practical fix.

What we do, in plain terms:

we place a tuned ion exchange column after your main purification and conditioning steps, we control pH and conductivity to an operational window that favors your API, and we run a programmed salt gradient to elute impurities separately from the product. The result: charged traces and counter-ions are removed to regulatory targets, your sterile filter sees a clean feed, and QC waits collapse.

Why this matters to your bottom line:

• Faster approvals, faster shipments, more predictable batch timing: less time spent on rework and retesting.
• Higher effective yield: keep more product in the finished batch, reduce cost per gram.
• Lower consumables spend: fewer polishing cycles, longer resin life, less buffer used.
• Cleaner submissions: tighter impurity profiles make regulatory reviews smoother.

Get in touch:

📧: info@sanitech-engineers.com

🌐: www.sanitech-engineers.com

📞 +91-22-6907-5151

Note: "Recovery rates and processing improvements are representative of typical applications and will vary based on molecule type, starting material quality, target purity specifications, buffer systems, and operating conditions. Individual results require validation through process development with your specific protein or peptide."

29/09/2025

Insulin yield suffers when handoffs are not engineered. Start with capture chromatography, condition the eluent, then apply low-shear TFF with controlled TMP and temperature. Typical pilot gains include +20–30% recovery and 20–30% buffer savings.

Get in touch:

📧: info@sanitech-engineers.com

🌐: www.sanitech-engineers.com

📞 +91-22-6907-5151

Note: "Recovery rates and processing improvements are representative of typical applications and will vary based on molecule type, starting material quality, target purity specifications, buffer systems, and operating conditions. Individual results require validation through process development with your specific protein or peptide."

Sanitech Engineers

15/12/2025

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08/12/2025

02/12/2025

11/11/2025

10/11/2025

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