25/08/2023
Body fat, specifically adipose tissue, is not just a passive storage site for excess energy.
It's an endocrine organ.
Adipose tissue secretes a variety of molecules known as adipokines. Some of the most well-known adipokines include:
Leptin: This hormone regulates appetite and energy balance. In cases of obesity, leptin levels often rise, but the body becomes resistant to its appetite-suppressing effects.
Adiponectin: This is involved in regulating glucose levels and breaking down fatty acids. Its levels tend to decrease in obese individuals, contributing to insulin resistance.
TNF-α (Tumor Necrosis Factor-alpha): A pro-inflammatory cytokine. Elevated levels can lead to inflammation and insulin resistance.
IL-6 (Interleukin-6): Another pro-inflammatory cytokine. Similar to TNF-α, its levels increase with greater adiposity, leading to inflammation.
Reducing excess adipose tissue isn't just an aesthetic goal.
It's essential for hormonal health, appetite regulation, reducing inflammation, preventing insulin resistance, and enhancing cardiovascular function.
