Dr.Riad Ghorayeb

26/01/2026

26/01/2026

هيك كانت البداية وهيك النهاية الف الحمد لله على سلامة الأم والتوائم الثلاث

20/12/2025

📌 MOUNJARO vs. OZEMPIC:
The UPDATED KSA Clinician's Guide🧪

Navigating the GLP-1/GIP landscape? Here’s your evidence-based, practice-ready breakdown for optimal T2DM management.

🔥 1. MECHANISM OF ACTION:
• Ozempic (Semaglutide): Selective GLP-1 receptor agonist.
• Mounjaro (Tirzepatide): First-in-class dual GIP & GLP-1 receptor agonist—dual action for enhanced metabolic efficacy.
📊 2. EFFICACY DATA (Head-to-Head):
• HbA1c Reduction: SURPASS-2 trial confirmed Tirzepatide (all doses) superior to Semaglutide 1mg in glycemic control.
• Weight Loss: Tirzepatide demonstrates significantly greater weight reduction vs. Semaglutide in clinical outcomes.

🔹3. KSA-SPECIFIC GUIDANCE (UPDATED):
• SFDA Approval Status: Both approved for T2DM. Verify latest indications for obesity management.
• Formulary & Insurance (CCHI): Critical access factor! Coverage varies by institution/region—confirm prior to prescribing.
• Tolerability & Dosing: GI side effects (nausea, diarrhea) common. Emphasize slow titration protocols—key for community pharmacist counseling and medication adherence.
• Cost & Accessibility: Major consideration for long-term therapy—engage pharmacy early for patient support.

🎯 CLINICAL BOTTOM LINE:
• For Superior HbA1c & Weight Reduction: Current evidence strongly favors Mounjaro (Tirzepatide).
• For Proven Cardiovascular Benefit: Ozempic (Semaglutide) retains robust CVOT data (SUSTAIN-6) demonstrating cardiovascular risk reduction—foundational for high-CV-risk patients.

🤝 INTERPROFESSIONAL COLLABORATION IS KEY: Physicians, clinical pharmacists, and community pharmacists must align for optimal patient access, education, and follow-up.
🚨 FINAL TAKE: Choice depends on patient profile, glycemic/weight goals, CV risk, formulary status, and cost coverage. Stay updated with SFDA, SCFHS, and institutional guidelines.

29/10/2025

237 likes, 8 comments. “من المهم تاخدي طعم الإنفلونزا بفترة الحمل، لتحمي حالِك والجنين #الانفلونزا ”

26/10/2025

تشرفنا بزيارة الاحباب صاروا كبار الله يحميهم و يحفظهم ويبارك فيهم لاهلهم الغاليين

26/10/2025

I got over 500 reactions on my posts last week! Thanks everyone for your support! 🎉