24/08/2025
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An excerpt from my keynote presentation "Mechanisms of Action of Biomodulating Laser Therapy and Its Clinical Applications for Treating Cardiovascular Diseases, Diabetes Mellitus, Obesity, and Cancer Linked to Ecological Stressors" at the XX International Symposium โEcological and Physiological Problems of Adaptationโ on Friday, 27 June 2025, hosted by the Medical Institute of the Russian Peoplesโ Friendship University (RUDN) in Moscow, Russia.
Biomodulating Laser Therapy (BLT), also called photobiomodulation, is a noninvasive treatment using low-intensity red or infrared lasers with organ-specific frequencies to help reverse pathological processes.
Photons are absorbed by cellular photo-acceptors like cytochrome C oxidase in mitochondria, boosting ATP production and activating cellular metabolism.
The principal effects are as follows:
1. Inflammation is mitigated through the reduction of pro-inflammatory cytokine levels.
2. Oxidative stress is decreased by the activation of endogenous antioxidant systems.
3. Microcirculation is enhanced via the stimulation of neo-angiogenesis (formation of new blood vessels)
4. Cellular proliferation is modulated, resulting in cellular stimulation or suppression, including apoptosis induction in tumour cells.
5. The immune system is activated to bolster the body's defense against disease.
Biomodulating laser therapy is utilised clinically in the management of cardiovascular disorders due to its ability to achieve several therapeutic effects:
1. Enhancement of endothelial function and improvement of microcirculation;
2. Reduction or normalization of blood pressure;
3. Promotion of myocardial microcirculation, including neo-angiogenesis;
4. Considerable decrease in ischaemic myocardial areas;
5. Lowering of inflammation markers such as C-reactive protein.
The application of Biomodulating Laser Therapy has been associated with the following outcomes:
1. For ischaemic heart disease, episodes of angina pectoris (chest pain) were reported to have stopped, and normalization of ECG readings was observed.
2. In cases of myocardial infarction, a reduction of 80% in dead myocardial zones was noted.
3. For cardiac arrhythmia, a normal sinus rhythm was restored in 85% of cases.
4. In chronic cardiac insufficiency, improvements in left ventricular ejection fraction were observed, along with a decrease in Functional Class according to the New York Heart Association (NYHA).
This video explores the groundbreaking world of ๐๐ข๐จ๐ฆ๐จ๐๐ฎ๐ฅ๐๐ญ๐ข๐ง๐ ๐ฅ๐๐ฌ๐๐ซ ๐ญ๐ก๐๐ซ๐๐ฉ๐ฒ, a cutting-edge non-invasive approach that potentially transforms the treatment of chronic cardiovascular diseases.
Are you curious to learn more?
Watch the full video to understand the science behind how this advanced therapy could be vital to future cardiovascular treatment plans.
