02/03/2026
Leukaemia: What Are The Treatment Options?
Once leukaemia is confirmed, treatment is not the same for everyone.
It depends on:
- The type of leukaemia
- Whether it is acute or chronic
- The patient’s age
- Other medical conditions
Acute leukaemia requires urgent treatment.
Chronic leukaemia may sometimes be monitored first, or treatment may begin based on the situation.
The backbone of treatment for acute leukaemia is systemic chemotherapy. This involves a combination of drugs designed to destroy fast-growing cancer cells. The exact combination depends on the specific type of leukaemia. Side effects are carefully discussed before treatment begins.
Beyond chemotherapy, we now have more precise options.
Targeted therapy focuses on specific genetic or molecular changes driving the disease. Instead of treating broadly, these drugs aim directly at the abnormal mutation.
Immunotherapy works differently. It helps the body’s immune system recognise and attack leukaemic cells. Examples include:
- Monoclonal antibodies
- Immune checkpoint inhibitors
- CAR-T cell therapy
In selected patients, stem cell transplantation may be recommended. This involves replacing diseased bone marrow with healthy stem cells, either from a donor or from the patient. In some cases, radiation is given before transplantation to eliminate remaining leukaemic cells.
Watch this video to understand the different treatment options for leukaemia and how modern therapies have significantly improved outcomes.
Dr Sivakumar Palaniappan is a Consultant Haematologist at Pantai Hospital Kuala Lumpur, specialising in blood cancers, stem cell transplantation, and advanced cellular therapies.
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