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24/12/2022

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28/10/2022

Grateful for another valuable learning session from Head Dietician from Taiwan. Always good to unlearn and relearn.

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23/10/2022

Why a balanced healthy immune system is important 💪💪💪

08/09/2022

#中秋節 的滿月
是一年裡最圓最亮的時候
象徵著團聚、圓滿之意喔！
就像雙鶴家的文化♥

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03/09/2022

01/09/2022

🔥 Introduction to dendritic cells: it is a monocyte. When dendritic cells mature, they will protrude many dendritic like or pseudopodia like processes, which are similar to the dendrites of neurons. Dendritic cells usually exist in the skin membrane (mucous membrane) in contact with the outside world, such as the skin, the nose of the inner layer, the lung, the stomach and the inner layer of the intestine. Dendritic cells help the body recognize pathogens and initiate specific immune responses by taking, processing and presenting antigens to lymphocytes in lymph nodes and lymph organs

✅ A recent report published in Chinese herbal medicine by Guangzhou UTCM Institute of basic medicine pointed out that dendritic cells from the spleen of mice were cultured with Ganoderma triterpenes and cytokines (GM-CSF + IL-4). The results showed that dendritic cells significantly proliferated, and the effect was better than that of using Ganoderma triterpenes or cytokines alone; If only triterpenes are cultured with dendritic cells, dendritic cells will also proliferate, but the effect is not as obvious as that of using cytohormones alone

✅ Dendritic cells play a very important role in the immune system. They can influence T cells and subsequent immune responses. The above experiments show that Ganoderma triterpenes can directly promote dendritic cells. However, if they can be coordinated through cytohormones, the effect of dendritic cell proliferation will be better.

✅〔 Source: Wang B, Hu y, Li J.: effect of Ganoderma triterpene on promotion of dendritic cells from mouse spleen

🔥樹突狀細胞簡介: 是一種單核細胞。樹突狀細胞成熟時會伸出許多樹突樣或偽足樣突起，與神經元的樹突相似。樹突狀細胞通常存在於跟外界接觸的皮膜(黏膜)部位，比如皮膚、內層的鼻子、肺、胃與腸的內層。樹突狀細胞通過攝取、加工處理和遞呈抗原到淋巴結和淋巴器官中的淋巴細胞幫助機體識別病原體，啟動特異性免疫應答

✅廣州UTCM基礎醫學研究所最近一項發表在《中藥材》的報告指出，將取自小鼠脾臟的樹突細胞，與靈芝三萜類和細胞激素（GM-CSF + IL-4）一起培養，結果發現，樹突細胞顯著增殖，其效果比單獨使用靈芝三萜類或細胞激素要來得好；如果只以三萜類與樹突細胞一起培養，樹突細胞也會增殖，只是效果不如單獨使用細胞激素的效果明顯

✅樹突細胞在免疫系統裡扮演相當重要的角色，它會左右Ｔ細胞及後續的免疫反應，而上述的實驗告訴我們，靈芝三萜類能直接促進樹突細胞，不過若能透過細胞激素進行協調，樹突細胞增殖的效果會更好。

✅〔資料來源〕Wang B, Hu Y, Li J.: Effect of Ganoderma triterpene on proliferation of dendritic cells from mouse spleen.

30/08/2022

11/08/2022

Relationship between 🔥Li2Co3-induced # testicular toxicity and Ganoderma lucidum protection: Changes in Bax and c-Kit gene expression

✅ Ganoderma has received a lot of attention recently because of its potential medicinal activity. The purpose of this design experiment was to evaluate the beneficial effects of ganoderma extracts on the testicular toxicity and related injuries induced by lithium carbonate in mice.

✅ for this purpose, lithium carbonate is administered at a dose of 30 mg/kg, followed by oral 75, 150 mg/kg Ganoderma lucidum extract for 35 days. The results of Ganoderma lucidum extract analysis were determined by spectrophotometry to contain a large amount of polysaccharides, triterpenes and polyphenols.

✅, DPPH of Ganoderma lucidum extract showed high levels of free radical scavenging activity. IHR cross-section from lithium carbonate treatment group showed significant changes in trachytrin tubes

✅, lithium carbonate induces oxidative stress and produces MDA through lipid peroxidation. In addition, lithium carbonate initiates germ cell apoptosis by increasing Bax expression and reduces germ cell differentiation by downregulating c-Kit expression.

✅ CASA results showed a significant decrease in the # s***m count, # vitality and # vitality parameters in the lithium treatment group. It is clear that lithium carbonate causes serious damage to # male reproductive system and histopathological damage by producing # oxidative stress, but supplementing Ganoderma lucidum extract has a preventive effect and repairing induced damage

Source: Histiocytes October 2021; 72:101552。 doi: 10.1016/j.tice.2021.101552。 Epub May 8, 2021

🔥Li2Co3誘導的 #睾丸毒性與靈芝保護作用的關係：Bax和c-Kit基因表達的改變

✅靈芝由於其潛在的藥用活性，最近受到了很多關注。該設計實驗的目的是評估靈芝提取物對碳酸鋰誘導的小鼠睾丸毒性和相關損傷的有益作用。

✅為此目的，碳酸鋰的劑量為 30 mg/kg，然後口服 75、150 mg/kg 靈芝提取物，持續 35 天。靈芝提取物分析結果經分光光度法測定證明含有大量的多醣、三萜類和多酚類物質。

✅此外，靈芝提取物的 DPPH 測定顯示出高水平的自由基清除活性。蘇木精& 來自碳酸鋰處理組的伊紅橫截面在曲細精管中表現出顯著的改變

✅此外，碳酸鋰通過脂質過氧化誘導氧化應激並產生MDA。此外，碳酸鋰通過增加 Bax 表達啟動生殖細胞凋亡，並通過下調 c-Kit 表達減少生殖細胞分化。

✅CASA 的結果顯示，鋰治療組的 #精子數量、 #活力 和活力等參數顯著下降。很明顯，碳酸鋰通過產生 #氧化 應激對 #男性生殖系統 和組織病理學損傷造成嚴重損害，但補充靈芝提取物具有預防作用並修復誘發的損傷

資料來源:組織細胞2021 年 10 月；72:101552。 doi: 10.1016/j.tice.2021.101552。 Epub 2021 年 5 月 8 日

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