
25/09/2024
Tuberculosis (TB) is a bacterial infection caused by Mycobacterium tuberculosis, affecting the lungs and potentially other organs.
*Types of TB:*
1. Pulmonary TB (lung infection)
2. Extrapulmonary TB (infection outside the lungs)
3. Latent TB (asymptomatic, non-infectious)
4. Active TB (symptomatic, infectious)
5. Multidrug-resistant TB (MDR-TB)
6. Extensively drug-resistant TB (XDR-TB)
*Symptoms:*
1. Coughing (persistent, bloody)
2. Chest pain
3. Fatigue
4. Weight loss
5. Fever
6. Night sweats
7. Chills
*Transmission:*
1. Airborne transmission (inhalation)
2. Close contact with infected person
3. Contaminated surfaces or objects
*Diagnosis:*
1. Tuberculin skin test (TST)
2. Blood tests (IGRA)
3. Chest X-ray
4. Sputum smear microscopy
5. Culture test
*Treatment:*
1. Antibiotics (first-line: isoniazid, rifampicin, ethambutol, pyrazinamide)
2. Treatment duration: 6-12 months
3. Directly observed treatment, short-course (DOTS)
4. MDR-TB and XDR-TB require specialized treatment
*Prevention:*
1. Vaccination (BCG vaccine)
2. Screening high-risk individuals
3. Infection control measures (masks, ventilation)
4. Contact tracing
5. Education and awareness
*Complications:*
1. Respiratory failure
2. Heart problems
3. Spinal cord damage
4. Meningitis
5. Increased risk of HIV/AIDS
*Global Statistics:*
1. 10 million new cases annually
2. 1.5 million deaths annually
3. 1/4 of the world's population infected with latent TB
*Resources:*
1. World Health Organization (WHO)
2. Centers for Disease Control and Prevention (CDC)
3. National Institute of Allergy and Infectious Diseases (NIAID)
4. Stop TB Partnership
Would you like more information on tuberculosis or specific aspects of the disease?