21/07/2025
Genotype vs Blood Group: Know the Difference, Protect Your Health!
1. Definition:
Genotype refers to the genetic makeup of an individual, particularly the pair of alleles inherited from parents. In this context, it's often used to describe sickle cell traits like:
AA – Normal
AS – Sickle cell trait (carrier)
SS – Sickle cell anemia
AC, SC, etc. – Other variants
Blood Group refers to the classification of blood based on the presence or absence of antigens (A, B) and Rh factor on red blood cells. The main types are:
A, B, AB, O
Each can be positive (+) or negative (−) (based on Rh factor)
2. Inheritance:
Genotype is inherited only from your parents and remains the same for life.
Blood group is also inherited, but more related to transfusion and compatibility.
3. Medical Importance:
Genotype is crucial when choosing a life partner to avoid sickle cell complications in children.
Blood group is important for blood transfusion, pregnancy compatibility (especially Rh factor), and organ donation.
4. Testing:
Genotype test checks for hemoglobin variants.
Blood group test identifies ABO and Rh type.
Do you know your blood group and genotype?
