07/10/2025
Not Every Fruit Is Safe:
See How Grapefruit Can Turn Your MEDICINE into POISON
Grapefruit Juice + Medications 💊 ❌
How does grapefruit turn your drugs into poisons?
Grapefruit contains furanocoumarins, which irreversibly inhibit intestinal CYP3A4 (which is the enzyme that metabolize / breaks down most drugs in your body. what this means is that the drugs in your body at that time will no longer be broken down as supposed.
This leads to reduced first-pass metabolism and increased bioavailability of some drugs. Which means the drugs will remain in your body for a longer duration than expected .
Remember all drugs are also POISONS
which Drugs are most likely to be affected ?
1. Statins. Used in the management of cholesterol (e.g., simvastatin, atorvastatin)
2. Calcium channel blockers. Used in the management of high blood pressure (e.g., felodipine, Amlodipine, Nifedipine etc)
3. Immunosuppressants (e.g., cyclosporine)
4. Some benzodiazepines. Used in the management of anxiety, insomnia , seizure , epilepsy etc
Adverse Effects:
1. Toxicity from high plasma levels
2. Muscle breakdown (with statins)
3. Hypotension or bradycardia/ reduced heart rate (with calcium channel blockers)
4. Sedation or confusion (with benzodiazepines )
Conclusion: always take your medications 💊 with just water 💦. Do not take medications along with anything otherwise recommended by your doctor/ pharmacist. Because even your natural foods like fruit 🍎 and turn your drugs into toxic substances
I am Dr Best, your health advocate
Follow Dr Best on all social media platforms and do well to like, comment and share my posts.
See you on the next one