Kamal Thapa

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Biomedical Engineer | ART IUI IVF ICSI
ART Equipment Selection & Procurement | Site survey & Layout Designing | Calibration & Validation | ART Equipment Supply & Maintenance

13/03/2025
03/03/2025

The findings could help to design robots 🤯

03/03/2025

Male and female fertility function very differently.

Men remain fertile throughout their lives, while women have a limited reproductive window. This is because men continuously produce s***m, generating about 1,500 s***m per second, while women are born with a fixed number of eggs — approximately 1 million at birth.

That egg supply gradually declines without regeneration.

Each month, a woman releases a single egg that remains viable for only 12 to 24 hours, whereas s***m can survive in the female reproductive tract for up to three days.

While male fertility is relatively consistent from the time of puberty until *very* late in life, female fertility begins at puberty and ends with menopause, creating a clear biological distinction between the two.

That said, age plays a significant role in fertility decline for both genders, but its impact is more pronounced in women.

A woman’s chances of conceiving naturally drop from 25% when under age 30 to just 5% at age 40 and over. Men experience fertility decline starting around age 40 to 45, as testosterone levels and s***m quality decrease.

Infertility can affect both sexes, with 40% of cases linked to female factors, 30% to male factors, and 20% involving both partners.

Lifestyle choices, such as weight and smoking, also contribute to fertility challenges, alongside genetic factors that influence egg supply and s***m production.

learn more https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/age-and-fertility

03/03/2025

A new study shows that a father's stress leaves lasting marks on his s***m — influencing the development of his offspring.

This new research, published in the journal Molecular Psychiatry, delves into the field of epigenetics, which explores how environmental factors can alter gene expression without changing the underlying DNA sequence.

These epigenetic changes can act as molecular switches, turning genes on or off and influencing various biological processes. Researchers analyzed s***m samples from 58 men, most in their late 30s to early 40s.

The study revealed that men who reported high levels of childhood stress had different epigenetic profiles in their s***m compared to those who reported lower stress. These differences persisted even after accounting for other factors like smoking and drinking, suggesting that childhood experiences can leave lasting epigenetic marks.

The researchers also found differences in a specific small noncoding RNA molecule previously linked to brain development in mice, as well as variations in DNA methylation patterns near genes involved in early brain development. While these findings suggest a potential link between childhood stress and epigenetic changes in s***m that could influence offspring development, it's crucial to emphasize that this research is still preliminary. It's not yet confirmed whether these epigenetic changes are passed down to children or what their ultimate impact might be. Further research is needed to determine the extent to which these epigenetic modifications in s***m can affect the health and development of future generations.

learn more https://www.nature.com/articles/s41380-024-02872-3

19/02/2025

When the Nobel Prize for in vitro fertilisation (IVF) was announced, thousands of greetings poured in for the scientist behind its development, Robert Edwards:

"Congratulations - my partner & I are about to go into IVF. Without you we would have no hope. You have given hope to millions. Thank you."

IVF is a medical procedure whereby an egg is fertilised by s***m outside the body. More than 10% of all couples worldwide are infertile and today millions of individuals have been born thanks to IVF. Edwards explained how eggs mature and how s***m is activated. In cooperation with Patrick Steptoe he found a method for removing eggs from the ovaries, and with Jean Purdy he found a way to achieve fertilisation outside the body.

On this day in 1969, the results were presented in the journal Nature and in 1978 the first child was born as a result of IVF. 'In vitro' means a process taking place in a test tube, culture dish, or elsewhere outside a living organism.

Learn more about Edwards: https://bit.ly/3rcP9nB

04/02/2025

Bringing Dreams to Life – A Glimpse Inside Advanced IVF Lab!

Take a closer look at the cutting-edge technology that helps turn hope into reality! Our state-of-the-art IVF lab is equipped with the latest innovations, including ICSI setup, IVF workstation, COâ‚‚ box incubator, trigas benchtop incubator, stereo zoom microscope, and more. Every piece of equipment plays a crucial role in ensuring the highest success rates for fertility treatments.

With precision, expertise, and dedication, we are here to support your journey toward parenthood. Because every detail matters in creating new beginnings!

***mFreezing

"Thrilled to share the layout design of our state-of-the-art ART Lab Centre!Unlike conventional hospital OT setups, this...
03/02/2025

"Thrilled to share the layout design of our state-of-the-art ART Lab Centre!

Unlike conventional hospital OT setups, this specialized design is carefully planned to maximize lab efficiency and optimize outcomes. A well-structured layout isn’t just about aesthetics—it’s a key factor in enhancing success rates and ensuring the best possible care.

We’d love to hear your thoughts and feedback!"


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Bringing the Future of Fertility Care to Life!We are excited to share a glimpse of our state-of-the-art Modular Operatio...
03/02/2025

Bringing the Future of Fertility Care to Life!

We are excited to share a glimpse of our state-of-the-art Modular Operation Theatre (OT) and Advanced IVF/ART Lab! These images showcase the precision and innovation behind a modern fertility center, designed to provide the highest standards of care for aspiring parents.

Why Modular?
✅ Ultra-Clean Environment – Minimizes contamination, crucial for embryo development.
✅ Superior Air Filtration – HEPA filters ensure an optimal, particle-free atmosphere.
✅ Temperature & Humidity Control – Enhances lab efficiency and success rates.
✅ Durability & Flexibility – Easy to upgrade with advancing technology.

A well-designed modular IVF lab is not just about infrastructure—it’s about creating the perfect environment for life to begin. Stay tuned as we take a step closer to making world-class fertility care more accessible!


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Inside the IVF Lab – Where Science Creates Miracles!Welcome to our cutting-edge IVF Lab, the heart of fertility treatmen...
01/02/2025

Inside the IVF Lab – Where Science Creates Miracles!

Welcome to our cutting-edge IVF Lab, the heart of fertility treatment, where technology and expertise come together to create new possibilities.

✨ Key Technologies at Work:
🔹 ICSI (Intracytoplasmic S***m Injection) – Precision at the microscopic level to enhance fertilization.
🔹 Advanced Incubators – Creating the perfect environment for embryo development.
🔹 IVF Workstation – Ensuring a sterile and controlled space for delicate procedures.

Every detail in our lab is designed to turn hope into reality, supporting your journey to parenthood with the highest standards of care. đź’–

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"✨ A Glimpse Inside the IVF Lab – Where Science Meets Miracles! ✨Step into the heart of fertility treatment – our state-...
31/01/2025

"✨ A Glimpse Inside the IVF Lab – Where Science Meets Miracles! ✨

Step into the heart of fertility treatment – our state-of-the-art IVF Lab. This is where hope takes shape, with cutting-edge equipment ensuring the highest standards of care and precision.

🔬 ICSI (Intracytoplasmic S***m Injection) – Enhancing fertilization with precision micromanipulation
🌡️ Incubators – Providing the ideal environment for embryo development
🛠️ IVF Workstation – Maintaining a sterile, controlled space for delicate procedures

Every detail in our lab is designed to support life’s most beautiful journey – parenthood. 💖


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"Excited to share a glimpse of our newly set up state-of-the-art IVF lab in Kathmandu!Equipped with the latest technolog...
31/01/2025

"Excited to share a glimpse of our newly set up state-of-the-art IVF lab in Kathmandu!

Equipped with the latest technology, including the Heracell incubator, ICSI workstation, and a fully modular setup, this lab is designed to bring the best in assisted reproductive care. Proud to be part of this milestone!

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Sinamangal
Kathmandu
44600

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