
18/08/2025
If you can’t access insulin-specific tests like the HOMA-IR index, you need look no further than the ALT and AST readings on your standard liver enzyme panel.
New research shows that a higher ALT-to-AST ratio is a strong indicator of insulin resistance, especially in women.
And the best part? It’s such an easy test. You don’t even need to fast.
Other clues to insulin resistance include high triglycerides (>150 mg/dL or 1.7 mmol/L), low HDL, constant hunger, reactive hypoglycemia, and weight gain around the middle.
Insulin resistance is the most common hormonal condition and a driver of many downstream problems. So it’s worth knowing if you have it, not guessing.
Links to:
- the research paper: https://pubmed.ncbi.nlm.nih.gov/38758828/
- and my metabolism book: https://www.larabriden.com/metabolism-book/