08/04/2026
Thrilled to share this article co-authored by our very own Sandra Clair alongside Ray Kirk, Ian Douglass Coulter and Reinhard Saller.
When History Becomes Evidence: A Pragmatic Framework for Traditional Plant Medicines discussed the challenges of relying on RCTs when reviewing the evidence for traditional plant medicine.
This article presents the Pragmatic Historical Assessment (PHA) tool, a systematic framework developed to broaden the range of evidence sources used to evaluate the effectiveness and safety of traditional plant medicines (TPMs) in the European materia medica. Drawing on professional German-language medical and regulatory literature spanning 400 years, and using arnica (Arnica montana, Asteraceae) and St. John’s wort (Hypericum perforatum, Hypericaceae) as examples, the PHA tool enables cross-validation of data from historical medical texts, contemporary phytotherapy references, pharmacopeias, herbal monographs, and scientific studies, including RCTs.
It's available via the American Botancial Council at https://www.herbalgram.org/resources/herbalgram/issues/145/table-of-contents/hg145-feat-hxtpm/