Dr Najam’s Hearing Clinic (2025)

14/08/2025

30/07/2025

Two children got their C I this week through our partial sponsorship scheme. JazakAllah to all our sponsors.

20/07/2025

Big shout out to my newest top fans! 💎

Shahid Ali, Taimoor Akram, Nasarullah JaMali

Drop a comment to welcome them to our community, fans

19/07/2025

Shout out to my newest followers! Excited to have you onboard!

Muhammad Hassan Raza, Shahid Badar

13/07/2025

Parents C I training workshop at Our Cochlear Implant Center

07/07/2025

https://www.facebook.com/share/16VTpVnjhJ/?mibextid=wwXIfr

Researchers say this type of treatment for deafness is ‘just the beginning.’
A single injection of a breakthrough gene therapy may soon be able to reverse hearing loss within weeks, according to new research from Sweden’s Karolinska Institutet.

The therapy was tested in a small clinical trial involving children and adults with congenital deafness or severe hearing impairment caused by mutations in the OTOF gene. This gene is responsible for producing otoferlin, a protein essential for transmitting sound signals from the ear to the brain. Without it, individuals are left unable to process sound despite having otherwise healthy hearing structures.

In the trial, a harmless, synthetic version of the adeno-associated virus was used to deliver a healthy copy of the OTOF gene directly into the inner ear via a single injection. The therapy led to rapid and significant improvements. Within just one month, most participants began to recover their hearing, and by six months, all ten showed measurable gains.

On average, the volume of perceptible sound improved dramatically - from 106 decibels (near total deafness) to 52 decibels (mild hearing loss). Children between the ages of five and eight responded the best, with one seven-year-old girl regaining nearly full hearing and holding regular conversations just four months post-treatment.

Importantly, the study, published in Nature Medicine, found that the treatment was both safe and well-tolerated. No serious adverse effects were reported during the six- to twelve-month follow-up period, with the most common reaction being a temporary reduction in neutrophils, a type of white blood cell. This marks the first time this gene therapy approach has been tested in teenagers and adults, expanding the potential reach of the treatment.

Dr. Maoli Duan, one of the lead researchers, emphasized the life-changing potential of the therapy and noted that OTOF is just the beginning. The team is now exploring treatments for other common genetic causes of deafness, including GJB2 and TMC1. While these present more complex challenges, early animal studies have been promising, and researchers are hopeful that a wide range of genetic hearing disorders will eventually become treatable.

Monday	00:30 - 20:00
Tuesday	10:30 - 20:00
Wednesday	10:30 - 20:00
Thursday	10:30 - 20:00
Friday	10:30 - 20:00
Saturday	10:30 - 20:00

Dr Najam’s Hearing Clinic

14/08/2025

30/07/2025

20/07/2025

19/07/2025

13/07/2025

07/07/2025

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