Medico Info1

Medico Info1 🩺 Cutting-Edge Medical Insights
⚕️ From Med Learner ➤ Lifesaver
📩 DM for Collabs and Promotions

Why NSAIDs Cause Gastric Ulcers?
04/01/2026

Why NSAIDs Cause Gastric Ulcers?

Anemia Classification
04/01/2026

Anemia Classification

What's your diagnosis and treatment plan?Comment your answer
03/01/2026

What's your diagnosis and treatment plan?
Comment your answer

Pathogonomic Signs
03/01/2026

Pathogonomic Signs

Cranial Nerve Lesion Causes
03/01/2026

Cranial Nerve Lesion Causes

Moxifloxacin
02/01/2026

Moxifloxacin

Cephradine
02/01/2026

Cephradine

Lincomycin
01/01/2026

Lincomycin

Co-Amoxiclav
01/01/2026

Co-Amoxiclav

Vacutainer Tube Guide
30/12/2025

Vacutainer Tube Guide

CefiximeClass: Third-generation cephalosporin (oral).Mechanism: Bactericidal. Inhibits bacterial cell wall synthesis by ...
29/12/2025

Cefixime

Class: Third-generation cephalosporin (oral).

Mechanism: Bactericidal. Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). Resistant to many beta-lactamases.

Spectrum: Broad Gram-negative coverage; retained Gram-positive activity.

· Gram-negative: Excellent coverage of Haemophilus influenzae, Moraxella catarrhalis, Neisseria gonorrhoeae (including penicillin-resistant strains), Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae, Salmonella & Shigella spp.
· Gram-positive: Covers Streptococcus pneumoniae (but not penicillin-resistant strains) and Streptococcus pyogenes. Not active against Staphylococcus aureus (MSSA or MRSA) or Enterococci.
· Gaps: Poor activity against Pseudomonas aeruginosa, anaerobes, and Listeria.

Key Uses:

· Uncomplicated gonorrhea (first-line, typically as a single dose with azithromycin for chlamydia coverage).
· Acute otitis media and bacterial sinusitis (when first-line amoxicillin fails or in areas with high beta-lactamase prevalence).
· Uncomplicated urinary tract infections (UTIs).
· Pharyngitis/Tonsillitis (alternative in penicillin allergy, except type I hypersensitivity).

Side Effects:

· Gastrointestinal: Diarrhea, nausea, abdominal pain.
· Hypersensitivity reactions: Rash, urticaria (cross-reactivity with penicillins ~5-10%).
· Less common: Headache, dizziness, vaginitis, transient elevation of liver enzymes.

Important:

· Use with caution in patients with penicillin allergy (contraindicated in type I/immediate hypersensitivity).
· No activity against MRSA, Enterococci, or Pseudomonas.
· May cause false-positive urinary glucose with copper reduction tests (Clinitest).
· Can be taken with or without food (absorption is slower but not reduced with food).

AmoxicillinClass: Aminopenicillin (Beta-Lactam Antibiotic)Mechanism: Inhibits bacterial cell wall synthesis by binding t...
29/12/2025

Amoxicillin

Class: Aminopenicillin (Beta-Lactam Antibiotic)

Mechanism: Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). Bactericidal.

Spectrum: Gram-positive cocci (non-penicillinase-producing S. pneumoniae, S. pyogenes, E. faecalis); some Gram-negative rods (H. influenzae, E. coli, P. mirabilis). Inactivated by beta-lactamases.

Key Uses:

· Otitis media, sinusitis, community-acquired pneumonia
· Streptococcal pharyngitis (requires 10-day course)
· Uncomplicated UTIs
· Helicobacter pylori eradication (in combination therapy)

Side Effects:

· Diarrhea, nausea, vomiting
· Non-allergic maculopapular rash (common in mononucleosis or CLL)
· Hypersensitivity reactions (urticaria to anaphylaxis)

Important:

· Contraindicated in patients with penicillin/beta-lactam hypersensitivity.
· Requires dose adjustment in renal impairment.
· Use with clavulanate (Augmentin) for beta-lactamase producing organisms.

Address

Lahore
05499

Website

Alerts

Be the first to know and let us send you an email when Medico Info1 posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Shortcuts

Share

Share on Facebook Share on Twitter Share on LinkedIn
Share on Pinterest Share on Reddit Share via Email
Share on WhatsApp Share on Instagram Share on Telegram

Category