Dental and Medical Problems

Dental and Medical Problems Dane kontaktowe, mapa i wskazówki, formularz kontaktowy, godziny otwarcia, usługi, oceny, zdjęcia, filmy i ogłoszenia od Dental and Medical Problems, Zdrowie i medycyna, Ulica K. Marcinkowskiego 2-6, Wroclaw.

Dental and Medical Problems is an international, peer-reviewed, open access journal covering aspects of oral sciences and general medicine, published bimonthly by Wroclaw Medical University.

🦷 Invisible Pain, Real ImpactA large meta-analysis by researchers from Wroclaw Medical University and Medical University...
14/04/2026

🦷 Invisible Pain, Real Impact

A large meta-analysis by researchers from Wroclaw Medical University and Medical University of Lublin shows that pain in the oral cavity and face is far more common than we tend to assume — even when it remains invisible in everyday functioning.

Across 155 studies and over 1.7 million people, nearly one in five individuals worldwide experiences this type of pain. Surprisingly, the highest prevalence is observed among younger populations rather than older ones.

🔬 Why it matters

▫️Orofacial pain often goes unnoticed, yet it affects eating, speaking, sleep, and concentration.
▫️It has multiple causes — from dental issues to muscular and neurological disorders.
▫️Its “invisibility” means many people adapt to it instead of seeking help.
▫️This is the first meta-analysis to estimate the global prevalence of oral and facial pain — turning scattered data into a clearer picture of how widespread this hidden burden really is.

📖 Read the full article: https://dmp.umw.edu.pl/en/article/2026/63/1/219/

🔊 Listen to the podcast: https://on.soundcloud.com/hlXUwkuJu66wjfBmMb

🔍 Can MRI-detected effusion explain TMJ pain? Evidence from a systematic reviewDiagnosing the source of temporomandibula...
07/04/2026

🔍 Can MRI-detected effusion explain TMJ pain? Evidence from a systematic review

Diagnosing the source of temporomandibular joint pain remains challenging, particularly when imaging findings and clinical symptoms do not align. This systematic review demonstrates that MRI-detected TMJ effusion is associated with pain in most studies, although the strength of this relationship is variable. Careful clinical assessment may often be sufficient to guide diagnosis and reduce unnecessary reliance on MRI, with implications for more efficient and cost-effective care.

This systematic review provides several clinically relevant implications:

🔸confirms joint effusion as a frequent imaging correlate of TMJ pain
🔸demonstrates stronger association of effusion with pain in the presence of internal derangement
🔸indicates limited specificity of effusion due to its occurrence in asymptomatic joints
🔸supports structured clinical examination as a useful predictor of effusion
🔸underscores the need for standardized approaches to pain assessment and MRI interpretation

🔗 Read more: https://dmp.umw.edu.pl/en/article/2025/62/6/1201/

🚨 Rethinking Orthodontic Treatment Need in Children – Evidence from PolandMalocclusion is highly prevalent in children, ...
31/03/2026

🚨 Rethinking Orthodontic Treatment Need in Children – Evidence from Poland

Malocclusion is highly prevalent in children, yet the actual need for orthodontic intervention remains poorly aligned with treatment delivery in many healthcare systems. This study shows that although 81.6% of children aged 9–12 present with malocclusion, only about one in four demonstrates a clear clinical need for treatment based on IOTN-DHC. These findings highlight the need for objective, standardized qualification criteria to improve clinical decision-making and optimize resource allocation in publicly funded orthodontic care.

The study provides several clinically relevant implications:

🔸high prevalence of malocclusion does not equate to universal treatment indication

🔸approximately 50% of children treated with removable appliances show little or no need for therapy

🔸lack of association between treatment need and treatment delivery suggests inefficiencies in current qualification systems

🔸implementation of IOTN-DHC or similar indices may improve prioritization of severe cases

🔸health policy should shift toward evidence-based allocation of orthodontic resources

🔗 Read more: https://dmp.umw.edu.pl/en/article/2025/62/6/1017/

🔬 Can lasers improve outcomes after endodontic retreatment?Persistent periapical lesions remain a major challenge in end...
24/03/2026

🔬 Can lasers improve outcomes after endodontic retreatment?

Persistent periapical lesions remain a major challenge in endodontic retreatment, largely due to the difficulty of eliminating microorganisms from the complex anatomy of the root canal system. This randomized clinical trial showed that combining Er:YAG laser-activated irrigation with 635-nm photobiomodulation significantly improved early healing of periapical lesions and reduced postoperative pain compared with conventional retreatment.

These findings suggest that laser-assisted protocols may enhance clinical outcomes while improving patient comfort during endodontic retreatment.

The study provides several clinically relevant implications:

🔸Er:YAG laser-activated irrigation improved early periapical lesion healing, with significantly smaller lesions observed at the 6-month follow-up

🔸photobiomodulation using a 635-nm diode laser reduced postoperative pain during the first 24–48 hours after retreatment

🔸combined laser protocol may enhance disinfection by improving irrigant pe*******on into complex root canal structures

🔸laser-activated irrigation may improve removal of debris and smear layer generated during mechanical instrumentation

🔸integration of laser-based adjunctive techniques may support more predictable retreatment outcomes in teeth with persistent periapical pathology

🔗 Read more: https://dmp.umw.edu.pl/en/article/2025/62/6/1079

📣 New issue! 📣The latest issue of Dental and Medical Problems (1/2026) brings together new research across oral medicine...
16/03/2026

📣 New issue! 📣

The latest issue of Dental and Medical Problems (1/2026) brings together new research across oral medicine, dentistry and related medical fields.

The issue opens with an editorial by Miguel Meira e Cruz exploring whether nocturnal yawning may serve as a clinical marker of arousal instability in patients with sleep-disordered breathing, offering an intriguing perspective on sleep bruxism and arousal instability.

The issue also features a comment by Frank Lobbezoo, Peter Wetselaar and Michail Koutris reflecting on two decades of the postgraduate Orofacial Pain and Dysfunction program at ACTA (Academisch Centrum Tandheelkunde Amsterdam) and the evolving role of interdisciplinary education in this field.

The research articles in this issue cover a wide range of topics, including:

• Oral health epidemiology and public health – trends in unmet denture needs among Polish seniors (PolSenior vs PolSenior2) and the prevalence of dental caries and saliva changes in youth swimmers

• Oral medicine and systemic health – analyses of oral adverse events following COVID-19 vaccination and the effectiveness of photodynamic therapy versus topical clobetasol in oral lichen planus

• Pain and sleep research – meta-analysis of the global prevalence of oral and facial pain and a preliminary study on the association between cervico-cranio-mandibular musculoskeletal function and obstructive sleep apnea

• Dental materials and digital dentistry – influence of thermal aging on surface roughness of conventional and 3D-printed materials used in intraoral appliance manufacturing, and bond strength of self-adhesive resin cements to CAD/CAM silicate ceramics

• Novel therapeutic technologies – in vitro evaluation of the effect of an Er:YAG laser with a fractional PS04 handpiece on microbial biofilm survival

📖 The entire issue is available in Open Access: https://dmp.umw.edu.pl/en/issue/2026/63/1/

🦷 Genomics in Implant Dentistry: Toward Personalized Implant TherapyDental implants have high survival rates, yet failur...
10/03/2026

🦷 Genomics in Implant Dentistry: Toward Personalized Implant Therapy

Dental implants have high survival rates, yet failures still occur and remain difficult to predict. This review highlights how genetic predispositions and epigenetic mechanisms influence inflammatory responses, bone remodeling and the success of osseointegration. Understanding these molecular pathways may open the door to precision implant dentistry by enabling better risk assessment and more personalized treatment strategies.

The review identifies several biological mechanisms that may influence implant outcomes and suggests important implications for clinical practice and research:
🔸Genetic variants in inflammatory mediators such as IL-1, IL-6 and TNF-α may increase susceptibility to peri-implant inflammation and bone loss.
🔸Variations in genes regulating bone metabolism, including RUNX2, COL1A1 and the vitamin D receptor, may influence bone formation and osseointegration.
🔸Dysregulation of the RANK/RANKL/OPG pathway may enhance osteoclast activity and accelerate peri-implant bone resorption.
🔸Matrix metalloproteinases (MMPs) may contribute to extracellular matrix degradation and tissue breakdown around implants.
🔸Epigenetic mechanisms, such as DNA methylation and microRNA regulation, may modulate osteoblast differentiation and bone healing.
🔸Emerging omics technologies and genomic screening may help identify patients at increased risk of implant complications and guide personalized therapy.

🔗 Read more: https://dmp.umw.edu.pl/en/article/2025/62/5/977

🔬 Topical Probiotics as Modulators of Oral Wound HealingOral wound healing remains challenging due to constant microbial...
03/03/2026

🔬 Topical Probiotics as Modulators of Oral Wound Healing

Oral wound healing remains challenging due to constant microbial exposure and limited evidence for safe, locally acting adjunctive therapies during the proliferation phase. This in vivo study shows that topical application of probiotics significantly improves collagen density, angiogenesis, re-epithelialization, and wound reduction compared with controls. The findings indicate that probiotics may represent a biologically sound strategy to support tissue repair and guide future translational and clinical research in oral surgery.

The results of this study suggest practical and research-oriented implications by:
🔸demonstrating measurable histological benefits of locally applied probiotics,
🔸supporting their role as adjuncts to conventional wound management,
🔸highlighting strain-dependent but overall consistent regenerative effects,
🔸providing a rationale for well-designed human clinical trials and protocol development.

🔗 Read more: https://dmp.umw.edu.pl/en/article/2025/62/4/681/

🦠 Post-COVID Tongue Lesions: What Dentists Need to KnowPersistent tongue changes after SARS-CoV-2 infection remain under...
24/02/2026

🦠 Post-COVID Tongue Lesions: What Dentists Need to Know

Persistent tongue changes after SARS-CoV-2 infection remain under-recognized in everyday practice, with limited data on their frequency, duration and response to treatment. This large retrospective study shows that multiple tongue lesions often coexist after COVID-19 and may persist for months or even years, while appropriate local therapy can significantly shorten symptom duration. These findings highlight the need for structured observation, timely intervention and oncological vigilance in post-COVID patients.

➡️ The analysis identifies 13 distinct types of tongue lesions, most commonly enlarged fungiform papillae, depapillation, strawberry tongue, and geographic tongue.

➡️ The results show that most lesions resolve spontaneously, but local treatment reduces symptom duration by approximately 50%.

➡️ The clinical observations emphasize the importance of specialist referral when multiple, persistent or atypical lesions coexist, including rare cases with malignant transformation.

🔗 Read more: https://dmp.umw.edu.pl/en/article/2025/62/4/619/

🔬 A recent study demonstrates that salivary metabolomic profiling can distinguish healthy individuals from patients with...
19/02/2026

🔬 A recent study demonstrates that salivary metabolomic profiling can distinguish healthy individuals from patients with precancerous lesions and oral cancer, potentially before clear clinical symptoms appear.

Using GC-MS, researchers identified a distinct metabolic fingerprint based on volatile organic compounds (VOCs) that objectively differentiates these groups.

❓Why it matters?

▫️Cancer-related metabolic changes leave detectable traces in saliva.
▫️Sample collection is non-invasive and feasible in dental practice.
▫️Molecular alterations may precede visible lesions.

If validated in larger cohorts, this approach could transform dental
offices into frontline detection sites, shifting diagnosis toward
earlier and more treatable stages.

📖 Read the full article: https://dmp.umw.edu.pl/en/article/2025/62/6/1109

🔊 Listen to the podcast:
https://on.soundcloud.com/1kEwnRLiYh12mS8yKY

🔬 Oral Lichen Planus and HPV: New Insights from Saliva-Based ResearchOral lichen planus is classified as a potentially m...
17/02/2026

🔬 Oral Lichen Planus and HPV: New Insights from Saliva-Based Research

Oral lichen planus is classified as a potentially malignant disorder, yet the role of human papillomavirus in its pathogenesis and cancer risk remains unclear and inconsistently reported. Using comprehensive salivary HPV genotyping, this study shows that high-risk HPV types (HPV-16 and HPV-18) were not detected in patients with oral lichen planus, while beta-HPV-49 was significantly more prevalent than in controls. These findings refine current risk assessment and indicate that viral involvement in oral lichen planus differs from that observed in other potentially malignant oral disorders.

The results suggest that:

🔸clinicians can provide evidence-based reassurance regarding the lack of association between oral lichen planus and HPV-16/18,

🔸oral lichen planus may have a distinct viral profile compared with other potentially malignant oral disorders,

🔸future longitudinal studies should focus on the biological role of beta-HPV types rather than classical oncogenic HPVs,

🔸saliva represents a valuable, non-invasive biomaterial for oral disease research.

🔗 Read more: https://dmp.umw.edu.pl/en/article/2025/62/6/1089/

🔬 New Clinical Evidence in Pediatric Dentistry: Er:YAG Laser vs. Conventional DrillingManaging deep caries in primary te...
10/02/2026

🔬 New Clinical Evidence in Pediatric Dentistry: Er:YAG Laser vs. Conventional Drilling

Managing deep caries in primary teeth is clinically demanding because young children often experience pain, anxiety, and limited ability to cooperate, and because evidence-based laser protocols for deciduous teeth are still scarce. This randomized clinical trial demonstrates that Er:YAG laser treatment can remove carious tissue without reported pain (VAS = 0) and without immediate deterioration of pulp vitality, although the procedure takes longer than conventional drilling. These results strengthen the case for minimally invasive, child-centered dentistry and offer data that may inform both everyday clinical choices and future research agendas.

The findings indicate that:

🔸laser-assisted caries removal can be a clinically effective alternative to rotary instruments in pediatric patients,
🔸the need for local anesthesia may be reduced, improving comfort and cooperation,
🔸specific Er:YAG parameters can be safely applied to enamel and dentin in primary teeth, and
🔸further long-term clinical studies are justified to assess pulpal and restorative outcomes.

🔗 Read more: https://dmp.umw.edu.pl/en/article/2025/62/4/579/



Prof. Marzena Dominiak
Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

🦷 Polishing or Glazing Zirconia? New Evidence After 5 Years of Simulated ToothbrushingMaintaining the long-term aestheti...
03/02/2026

🦷 Polishing or Glazing Zirconia? New Evidence After 5 Years of Simulated Toothbrushing

Maintaining the long-term aesthetics of monolithic zirconia restorations remains a clinical challenge, particularly under continuous exposure to daily toothbrushing and dentifrices. The findings of a recent study demonstrate that polishing increases translucency and results in smaller color changes than glazing, whereas glazing increases surface roughness and leads to the most pronounced aesthetic deterioration after brushing. These results have important implications for prosthodontic decision-making, material selection and the long-term aesthetic performance of zirconia-based restorations in clinical practice.

Key clinical implications:

🔸Polishing provides superior long-term color stability compared with glazing for multilayer 5Y-TZP zirconia

🔸Glazing increases surface roughness, which may negatively affect aesthetic durability

🔸Toothbrushing can induce clinically unacceptable color changes regardless of finishing method

🔸Finishing protocols should prioritize long-term optical stability, not only immediate appearance

🔗 Read more: https://dmp.umw.edu.pl/en/article/2025/62/5/875/


USP - Universidade de São Paulo

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Ulica K. Marcinkowskiego 2-6
Wroclaw
50-368

Godziny Otwarcia

Poniedziałek 08:00 - 16:00
Wtorek 08:00 - 16:00
Środa 08:00 - 16:00
Czwartek 08:00 - 16:00
Piątek 08:00 - 16:00

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