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Eswatini Pharmacy Society

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Eswatini Pharmacy Society

Empowering healthcare through knowledge and innovation.

Your trusted source for pharmaceutical and medical updates, tips, and insights to promote better health for all.

26/11/2025

Depo-Provera (medroxyprogesterone 150mg), a widely used injectable contraceptive, has been linked to serious health risks that are now the focus of growing legal action. While millions of women have relied on Depo-Provera for long-term birth control since its approval in 1992, new scientific studies have uncovered a troubling connection between the drug and the development of meningioma brain tumors.

These findings have sparked a wave of lawsuits across the USA, as women who have been diagnosed with meningiomas after using Depo-Provera are now seeking compensation for the harm they’ve suffered. As more evidence emerges, the number of claims against the drug’s manufacturer, Pfizer, is expected to increase.

20/11/2025

As we raise awareness about antimicrobial resistance (AMR), we must also acknowledge an often-overlooked factor—our genetics.

Certain people carry a variation in the MT-RNR1 gene that makes them highly sensitive to aminoglycoside antibiotics (like gentamicin or amikacin). For them, even a single dose can cause irreversible hearing loss.

This is where pharmacogenomics, the study of how our genes affect drug response—becomes vital. By integrating genetic testing into antimicrobial stewardship programs, we can protect patients, improve antibiotic safety, and promote smarter, personalized medicine.

💡 AMR awareness must go hand in hand with pharmacogenomic awareness.
Because the fight against resistance isn’t just about bacteria—it’s also about understanding the human genome.

02/10/2025

Preventing Lifestyle-Related Diseases
Chronic conditions such as diabetes, hypertension, arthritis, and gout usually develop slowly over many years. By the time symptoms appear, the disease process has often been ongoing for decades. Prevention and early lifestyle adjustments are key.

✅ Maintain a healthy weight – especially abdominal fat (waist circumference should ideally be less than half your height).
✅ Eat whole foods – prioritize natural proteins, healthy fats, fruits, and vegetables.
✅ Limit processed foods and refined sugars – these contribute to obesity, insulin resistance, and inflammation.
✅ Practice portion control or time-restricted eating – some people benefit from eating 2 balanced meals daily.
✅ Get quality sleep – 7–8 hours of consistent rest supports metabolism and reduces stress hormones.
✅ Stay active – regular exercise improves cardiovascular health, bone strength, and joint flexibility.
✅ Get sunlight safely – helps with Vitamin D production, which is important for bone and immune health.
✅ Manage stress – chronic stress contributes to high blood pressure, weight gain, and poor immunity.

Remember: Preventing disease is far easier (and cheaper) than treating it once it develops.

25/09/2025

💊✨ Happy Pharmacists Day! ✨💊

Today, we celebrate the guardians of safe medicine use — Pharmacists!
From ensuring the right drug, at the right dose, to guiding patients with care and compassion, pharmacists are the heartbeat of healthcare.

🌍 Thank you for your commitment, knowledge, and impact in making healthier communities.

👏 Tag a pharmacist and let them know how much you appreciate them!

18/09/2025

💉 Depo-Provera (medroxyprogesterone 150mg injection) is a widely used contraceptive.
While effective, long-term use has been linked to rare cases of meningioma (a brain tumor).

✅ This doesn’t mean everyone will develop it—but it’s an important risk to be aware of.
🧠 Your healthcare provider should discuss this with you before starting or continuing therapy.

🔑 Always ask questions. Informed patients make safer choices.

17/09/2025

Skin bleaching is never worth the risk!

Those "miracle" creams may promise to lighten your skin overnight — but damage can last an entire lifetime.

⚡ Short-term: burning, redness, thin
⚡ Long-term: darker splotches, stretchmarks, skin cancer risk, even mercury poisoning which can harm your kidneys and nerves.

Healthy is beautiful — across all skin tones.

Instead of risky shortcuts, choose safe treatments and experienced advice to treat your skin problems.

✨ Accept the skin you're in — it's unique, it's sturdy, it's yours.

26/08/2025

Pharmacogenomic (PGx) information is essential for precision medicine, enabling drug prescriptions to be personalized according to an individual's genetic background. Almost all individuals will carry a genetic marker that affects their drug response, so the ideal drug prescription for these individuals will differ from the population-level guidelines. Currently, PGx information is often not available at first prescription, reducing its effectiveness.

24/08/2025

Many chronic and “incurable” illnesses—like type 2 diabetes, cardiovascular disease, hypertension, fatty liver disease, some cancers, and even certain autoimmune conditions—are strongly influenced by diet and lifestyle factors.
At EPS, we encourage the usage of herbal remedies–especially those suffering from chronic and autoimmune diseases—under the supervision of their healthcare practitioners.

13/08/2025

Many people, especially those selling herbal products on social media, often say these natural remedies don’t have any side effects. But that’s not quite true. Just like regular medicines, herbal products can affect how our bodies process drugs. Our liver uses special enzymes, called cytochrome P450, to break down many medicines and herbs. When certain herbs or foods change how these enzymes work, it can cause problems with how drugs behave in our bodies.

For example, St John’s wort, a common herbal supplement, can speed up an enzyme called CYP3A4. This means it can lower the amount of some medicines in your blood—like cyclosporine, a drug that prevents organ rejection after transplants—making it less effective.

Similarly, smoking to***co speeds up another enzyme, CYP1A2, which reduces levels of clozapine, a medicine used for obsessive-compulsive disorder. This can make the treatment less successful.

On the flip side, grapefruit juice works in the opposite way by blocking CYP3A4. This causes some medicines—like ritonavir, methadone, and certain heart drugs—to build up to higher levels in your body, which could be harmful if you consume them together.

So, while herbal remedies and natural foods can be helpful, they’re not always harmless. It’s important to be aware of how they might interact with your medications and talk to your healthcare provider before combining them.

12/08/2025

Pharmacogenetic polymorphisms can affect the extent of activity of organic anion transporting polypeptides (OATPs) in much the same way they affect the activity of Cytochrome P 450 isoenzymes.

08/06/2025

It's disheartening when our attempts to help as clinicians are misinterpreted as hostility. We are not your enemies — we are here to protect your health.

Some medications that are ordered or taken without a prescription can have serious side effects, including suicidal thoughts and other mental health risks (e.g. some antidepressants). These are not just pills — they’re powerful substances that require proper evaluation, medical history review, and counseling to ensure safe and effective use.

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