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29/10/2025

28/10/2025

Scientists have achieved a groundbreaking milestone by using genetically modified microbes to target and shrink tumours. These specially engineered microbes are designed to seek out cancer cells while sparing healthy tissue, offering a precision approach that could revolutionise cancer treatment.

In laboratory studies, the microbes successfully infiltrated tumours, releasing therapeutic compounds that slowed growth and, in some cases, reduced tumour size significantly. This approach represents a new frontier in oncology, combining synthetic biology with medicine to create targeted, effective therapies.

Experts believe this method could pave the way for treatments with fewer side effects compared to traditional chemotherapy and radiation. While still in early stages, clinical trials are being planned to explore safety and effectiveness in humans.

This discovery underscores the incredible potential of biotechnology to transform medicine and offers hope for millions affected by cancer worldwide. The era of living medicines may be closer than we ever imagined.

28/10/2025

A group of researchers can now look more closely at oligomers - nanoscale protein assemblies that have emerged as a possible cause of Parkinson's disease - because they developed a way to see them in postmortem brain tissue for the first time. Read more: http://ms.spr.ly/6183sCxgh

28/10/2025

When you sleep, your brain does not shut down. Instead, it shifts into a highly active problem-solving mode. During REM sleep, brain activity actually surpasses levels seen when you are awake, consuming about 20 percent more energy than during your most focused conscious moments. While you rest, your mind runs millions of mental simulations, testing different scenarios and exploring solutions to challenges you faced during the day.

Those sudden “aha” moments in the shower or while walking are not random. They are the result of your brain delivering insights generated during its overnight processing session. By combining information from multiple experiences, the brain can identify patterns and solutions that may seem elusive when you are actively thinking. Research shows that people who sleep on a problem are more than twice as likely to solve it compared to those who remain awake trying to work it out.

Dreaming is far from a passive state. It is an active workshop where your subconscious sorts, connects, and troubleshoots. Recognizing this turns sleep into a powerful tool for creativity, learning, and decision-making. Your nightly dreams are the brain’s way of quietly solving the puzzles you encounter in life, preparing you for new insights and breakthroughs with each morning you wake.

28/10/2025

The newborn stage is basically: “Is the baby too hot? Too cold? Breathing? Not breathing too hard? Should I Google it?” 😅

28/10/2025

Those with brittle diabetes can see blood sugars swing wildly high and low without explanation or logical predictability: https://diabetesstrong.com/brittle-diabetes/

28/10/2025

We're often told to eat small, frequent meals throughout the day. But groundbreaking research reveals that this constant grazing may be preventing our bodies from activating a powerful, built-in "repair mode."

Your body is designed to run on two different fuel systems. When we eat constantly, we only use one: glucose. A landmark 2019 review explains that when you practice intermittent fasting, you force your body to flip a crucial "metabolic switch" and start using its other fuel source: stored fat.

This switch is the key. It signals your body to begin a deep process of cellular repair and stress resistance.

The conclusions from this review are powerful. Researchers found this natural process is directly linked to improved insulin sensitivity, lower blood pressure, and a lower resting heart rate—all critical for long-term heart health. It also helps enhance your brain's plasticity, which supports memory and cognitive function.

For those committed to a long, healthy life and fending off age-related decline, this is a profound insight. It shows that by simply changing when you eat, you can unlock your body's own system for healing, a natural strategy for longevity that is completely free.

For those who want to see the science, this landmark review is published in The New England Journal of Medicine.

Source: de Cabo, R., & Mattson, M. P. (2019). "Effects of Intermittent Fasting on Health, Aging, and Disease." The New England Journal of Medicine, 381(26), 2541–2551.

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28/10/2025

A large proportion of the population has abdominal obesity despite a normal BMI, and these individuals are at increased cardiometabolic risk, two new studies found. http://ms.spr.ly/6183t6BPV

28/10/2025

Primary sclerosing cholangitis (PSC) causes inflammation and scarring of the bile ducts. This rare liver disease is often accompanied by inflammatory bowel disease (IBD). Together, these diseases increase the risk of colorectal cancer by more than sixfold compared to the general population.

Until recently, it wasn't clear whether that increased colorectal cancer risk extended to people with PSC alone, but Mayo Clinic researchers have helped answer this question.

Learn more: https://mayocl.in/4oEvPgH

28/10/2025

High cholesterol can be trouble. Find out if you’re doing things that can make it harder to keep your numbers in check. https://wb.md/47vDS9C

28/10/2025

Nearly half of American adults have high blood pressure, putting them at higher risk for stroke and heart disease. The only way to know if your BP is in a normal range is to measure it.