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Laser Therapy U, Atlanta, GA (2025)

04/21/2025

Join Dr. Christopher Carraway as he explores using PBM protocols for general health and well-being.
Key Talking Points:
- Understanding how PBM can be integrated into general health strategies
- Discover how PBM facilitates recovery and supports ongoing wellness as part of the continuum of care
- Explore practical protocols for maintaining health and preventing crises
- Review relevant research and case studies that support these practices

Registration: https://register.gotowebinar.com/register/1226165917853712981?source=social

04/18/2025

𝐋𝐚𝐬𝐞𝐫 𝐓𝐡𝐞𝐫𝐚𝐩𝐲 𝐟𝐨𝐫 𝐈𝐧𝐜𝐢𝐬𝐢𝐨𝐧 𝐇𝐞𝐚𝐥𝐢𝐧𝐠 𝐢𝐧 𝟗 𝐃𝐨𝐠𝐬
Wardlaw, et.al

Laser therapy is becoming common place in veterinary medicine with little evidence proving efficacy or dosages. This study evaluated surgical wound healing in canines. Twelve Dachshunds underwent thoraco-lumbar hemilaminectomies for intervertebral disc disease (IVDD). Digital photographs were taken of their incisions within 24 h of surgery and 1, 3, 5, 7, and 21 days postoperatively. The first three dogs were used to create a standardized scar scale to score the other dogs' incision healing. The remaining 9 dogs were randomly assigned to either receive 8 J/cm2 laser therapy once a day for 7 days or the non-laser treated control group. Incision healing was scored based on the scar scale from 0 to 5, with zero being a fresh incision and five being completely healed with scar contraction and hair growth. All scar scores significantly improved with increasing time from surgery (

04/17/2025

𝐖𝐨𝐮𝐧𝐝 𝐏𝐡𝐨𝐭𝐨𝐛𝐢𝐨𝐦𝐨𝐝𝐮𝐥𝐚𝐭𝐢𝐨𝐧 𝐓𝐫𝐞𝐚𝐭𝐦𝐞𝐧𝐭 𝐎𝐮𝐭𝐜𝐨𝐦𝐞𝐬 𝐢𝐧 𝐀𝐧𝐢𝐦𝐚𝐥 𝐌𝐨𝐝𝐞𝐥𝐬
Alondra Lopez, Cord Brundage

The possibilities that photobiomodulation has brought on to the medical field are ever expanding and the scope it has reached is infinite. Determining how this relatively new treatment technique can be incorporated into the veterinary medical field is of interest to many medical professionals. In this review, we examine the treatment outcomes of low-level-laser therapy (LLLT) in different animal models to pinpoint any similarities between the studies. A search was conducted to identify LLLT studies using different animal models with an open or closed wound. The studies were compared to identify the laser parameters that resulted in positive treatment outcomes. The overall result of the studies examined indicated that daily laser exposure at a wavelength of a 600 or 800 nm range was the most beneficial across the rodent studies regardless of health status or wound type. More studies on rabbit, canine, and equine models are needed to explain the inconsistent results reviewed and find the correct treatment parameters for these species. Further research involving LLLT studies that focus on different factors including health status, treatment interval, wavelength, and energy density is needed to help validate our knowledge about the efficacy of using photobiomodulation in the veterinary medical field.

https://pmc.ncbi.nlm.nih.gov/articles/PMC6699315/

04/16/2025

𝐏𝐡𝐨𝐭𝐨𝐩𝐡𝐲𝐬𝐢𝐜𝐚𝐥 𝐌𝐞𝐜𝐡𝐚𝐧𝐢𝐬𝐦𝐬 𝐨𝐟 𝐏𝐡𝐨𝐭𝐨𝐛𝐢𝐨𝐦𝐨𝐝𝐮𝐥𝐚𝐭𝐢𝐨𝐧 𝐓𝐡𝐞𝐫𝐚𝐩𝐲 𝐚𝐬 𝐏𝐫𝐞𝐜𝐢𝐬𝐢𝐨𝐧 𝐌𝐞𝐝𝐢𝐜𝐢𝐧𝐞
Liebert, et.al

[...] Herein, we propose a number of mechanisms of PBM that do not depend on cytochrome c oxidase. These include the photophysical aspects of PBM and the interactions with biophotons and mechanotransductive processes. These hypotheses are contingent on the effect of light on ion channels and the cytoskeleton, the production of biophotons, and the properties of light and biological molecules. Specifically, the processes we review are supported by the resonant recognition model (RRM). This previous research demonstrated that protein micro-oscillations act as a signature of their function that can be activated by resonant wavelengths of light. We extend this work by exploring the local oscillatory interactions of proteins and light because they may affect global body circuits and could explain the observed effect of PBM on neuro-cortical electroencephalogram (EEG) oscillations. In particular, since dysrhythmic gamma oscillations are associated with neurodegenerative diseases and pain syndromes, including migraine with aura and fibromyalgia, we suggest that transcranial PBM should target diseases where patients are affected by impaired neural oscillations and aberrant brain wave patterns. This review also highlights examples of disorders potentially treatable with precise wavelengths of light by mimicking protein activity in other tissues, such as the liver, with, for example, Crigler-Najjar syndrome and conditions involving the dysregulation of the cytoskeleton. PBM as a novel therapeutic modality may thus behave as “precision medicine” for the treatment of various neurological diseases and other morbidities. The perspectives presented herein offer a new understanding of the photophysical effects of PBM, which is important when considering the relevance of PBM therapy (PBMt) in clinical applications, including the treatment of diseases and the optimization of health outcomes and performance.

https://www.mdpi.com/2227-9059/11/2/237

04/10/2025

Many are familiar with the remarkable benefits of Photobiomodulation (PBM) for acute conditions such as pain, edema, inflammation, and muscle spasms. With over 9,300 peer-reviewed scientific papers available via the National Institutes of Health, the efficacy of PBM is well-documented for a wide range of conditions related to crisis and rehabilitation. The benefits of PBM can extend to everyday care as well for those not in recovery mode.

Join Dr. Christopher Carraway as he explores using PBM protocols for general health and well-being. He will review the concept of the Continuum of Care, which emphasizes the transition from acute crisis management to repair and recovery with PBM. Additionally, Dr. Carraway will discuss using PBM for supportive care to enhance overall health, preserve lifestyle quality, and enrich life enjoyment.

Key Talking Points:
- Understanding how PBM can be integrated into general health strategies
- Discover how PBM facilitates recovery and supports ongoing wellness as part of the continuum of care
- Explore practical protocols for maintaining health and preventing crises
- Review relevant research and case studies that support these practices

Register Here: https://attendee.gotowebinar.com/register/1226165917853712981?source=social

03/28/2025

𝐓𝐫𝐚𝐧𝐬𝐜𝐮𝐭𝐚𝐧𝐞𝐨𝐮𝐬 𝐥𝐢𝐠𝐡𝐭 𝐩𝐞𝐧𝐞𝐭𝐫𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐬𝐢𝐦𝐮𝐥𝐭𝐚𝐧𝐞𝐨𝐮𝐬 𝐬𝐮𝐩𝐞𝐫𝐩𝐮𝐥𝐬𝐞𝐝 𝐚𝐧𝐝 𝐦𝐮𝐥𝐭𝐢𝐩𝐥𝐞 𝐰𝐚𝐯𝐞𝐥𝐞𝐧𝐠𝐭𝐡 𝐩𝐡𝐨𝐭𝐨𝐛𝐢𝐨𝐦𝐨𝐝𝐮𝐥𝐚𝐭𝐢𝐨𝐧 𝐭𝐡𝐞𝐫𝐚𝐩𝐲 𝐢𝐧 𝐥𝐢𝐯𝐢𝐧𝐠 𝐝𝐨𝐠 𝐭𝐢𝐬𝐬𝐮𝐞
Hoisang, et.al

Photobiomodulation therapy (PBMT) is used as an adjunctive therapy for wound healing, pain relief and rehabilitation. The pe*******on of light to the target tissue is the crucial factor. The aim of this study was to investigate the potential pe*******on of simultaneous superpulsed and multiple wavelength (SPMW) PBMT on living tissue in dogs. Twenty client-owned dogs were anesthetized and underwent abdominal surgery. The PMBT device was set at 50 Hz and delivered light for 60 sec at different distances; at 0 cm (contact) and 1 cm tissue-device distance (noncontact). The power meter was placed and measured the mean output power (MOP) under the skin tissue only and the combination of skin and muscle tissue. The average thickness of skin was 2.97 mm (ranging from 1.7 to 4.3 mm) and
the combination of skin and muscle tissue thickness was 15.87 mm (ranging from 10.0 to 30.0 mm). For skin tissue, MOP was found to be at 13.00±4.99 mW and 3.47±1.79 mW using the skin contact and non-contact mode, respectively.
For the combination of skin and muscle tissue, MOP was found to be at 1.46±1.11 mW and 0.35±0.51 mW using the skin contact and non-contact mode, respectively. The MOP of skin contact was significantly greater than the non-contact both on skin tissue only and the combination of skin and muscle tissue (P

03/27/2025

𝐀𝐜𝐮𝐭𝐞 𝐄𝐟𝐟𝐞𝐜𝐭𝐬 𝐨𝐟 𝐏𝐡𝐨𝐭𝐨𝐛𝐢𝐨𝐦𝐨𝐝𝐮𝐥𝐚𝐭𝐢𝐨𝐧 𝐓𝐡𝐞𝐫𝐚𝐩𝐲 𝐂𝐨𝐦𝐛𝐢𝐧𝐞𝐝 𝐰𝐢𝐭𝐡 𝐒𝐭𝐚𝐭𝐢𝐜 𝐌𝐚𝐠𝐧𝐞𝐭𝐢𝐜 𝐅𝐢𝐞𝐥𝐝 𝐢𝐧 𝐂𝟐𝐂𝟏𝟐 𝐌𝐮𝐬𝐜𝐥𝐞 𝐂𝐞𝐥𝐥𝐬 𝐄𝐱𝐩𝐨𝐬𝐞𝐝 𝐚𝐧𝐝 𝐍𝐨𝐭 𝐄𝐱𝐩𝐨𝐬𝐞𝐝 𝐭𝐨 𝐇𝟐𝐎𝟐
Ferlito, et.al

Photobiomodulation (PBM) has been applied in biomedical technology to improve cellular responses. Specifically in sports medicine, it is used to accelerate metabolic and structural repair and adaptation in skeletal muscle under stress overload. Currently, PBM has been associated with static Magnetic Field (sMF) in clinical applications, enhancing the effects displayed by PBM when used in isolation. However, the biochemical and molecular effects of PBM-sMF in myoblasts remain unknown. This study aimed to investigate the effects of PBM combined with static magnetic field (PBM-sMF) at different doses in C2C12 muscle cells in the presence or absence of hydrogen peroxide (H2O2), a standard oxidant. Different spectrophotometric and fluorometric assays were conducted after cellular treatments. PBM-sMF was shown to be effective compared to H2O2 regarding cell viability and release of nitric oxide (NO), dsDNA, and reactive oxygen species (ROS) levels. It positively modulated mitochondrial membrane potential (ΔΨm) and cytochrome c oxidase (COX) activity under normal conditions and restored both to normal levels when impacted by H2O2. Regarding apoptosis, the recovery in viable cells observed on PBM-sMF treated cells was dose-dependent. In conclusion, PBM-sMF has a biphasic effect in normal and oxidative environments and may differently modulate myoblast cells depending on their redox status.

Open Access: https://www.mdpi.com/2076-3417/14/22/10221

03/25/2025

𝐓𝐡𝐞 𝐞𝐱𝐩𝐫𝐞𝐬𝐬𝐢𝐨𝐧 𝐨𝐟 𝐨𝐩𝐬𝐢𝐧𝐬 𝐢𝐧 𝐭𝐡𝐞 𝐡𝐮𝐦𝐚𝐧 𝐬𝐤𝐢𝐧 𝐚𝐧𝐝 𝐢𝐭𝐬 𝐢𝐦𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧𝐬 𝐟𝐨𝐫 𝐩𝐡𝐨𝐭𝐨𝐛𝐢𝐨𝐦𝐨𝐝𝐮𝐥𝐚𝐭𝐢𝐨𝐧: 𝐀 𝐒𝐲𝐬𝐭𝐞𝐦𝐚𝐭𝐢𝐜 𝐑𝐞𝐯𝐢𝐞𝐰
Susie Suh, Elliot H. Choi, Natasha Atanaskova Mesinkovska

Background: Skin is the organ most extensively exposed to light of a broad range of wavelengths. Several studies have reported that skin expresses photoreceptive molecules called opsins. However, the identity and functional role of opsins in the human skin remain elusive. We aim to summarize current scientific evidence on the types of opsins expressed in the skin and their biological functions.
Methods: A primary literature search was conducted using PubMed to identify arti-cles on dermal opsins found in nonhuman animals and humans.
Results: Twenty-two articles, representing, however, a non-exhaustive selection of the scientific papers published in this specific field, met the inclusion criteria. In non-human animals, opsins and opsin-like structures have been detected in the skin of fruit fly, zebrafish, frog, octopus, sea urchin, hogfish, and mouse, and they mediate skin color change, light avoidance, shadow reflex, and circadian photoentrainment. In humans, opsins are present in various skin cell types, including keratinocytes, mel-anocytes, dermal fibroblasts, and hair follicle cells. They have been shown to mediate wound healing, melanogenesis, hair growth, and skin photoaging.
Conclusion: Dermal opsins have been identified across many nonhuman animals and humans. Current evidence suggests that opsins have biological significance beyond light reception. In nonhuman animals, opsins are involved in behaviors that are critical for survival. In humans, opsins are involved in various functions of the skin although the underlying molecular mechanisms remain unclear. Future investigation on elu-cidating the mechanism of dermal opsins will be crucial to expand the therapeutic benefits of photobiomodulation for various skin disorders.

Full paper: https://onlinelibrary.wiley.com/doi/epdf/10.1111/phpp.12578

03/24/2025

𝐌𝐀𝐒𝐂𝐂/𝐈𝐒𝐎𝐎 𝐜𝐥𝐢𝐧𝐢𝐜𝐚𝐥 𝐩𝐫𝐚𝐜𝐭𝐢𝐜𝐞 𝐠𝐮𝐢𝐝𝐞𝐥𝐢𝐧𝐞𝐬 𝐟𝐨𝐫 𝐭𝐡𝐞 𝐦𝐚𝐧𝐚𝐠𝐞𝐦𝐞𝐧𝐭 𝐨𝐟 𝐦𝐮𝐜𝐨𝐬𝐢𝐭𝐢𝐬 𝐬𝐞𝐜𝐨𝐧𝐝𝐚𝐫𝐲 𝐭𝐨 𝐜𝐚𝐧𝐜𝐞𝐫 𝐭𝐡𝐞𝐫𝐚𝐩𝐲
Lalla, et.al.

BACKGROUND
Mucositis is a highly significant, and sometimes dose‐limiting, toxicity of cancer therapy. The goal of this systematic review was to update the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO) Clinical Practice Guidelines for mucositis.

METHODS
A literature search was conducted to identify eligible published articles, based on predefined inclusion/exclusion criteria. Each article was independently reviewed by 2 reviewers. Studies were rated according to the presence of major and minor flaws as per previously published criteria. The body of evidence for each intervention, in each treatment setting, was assigned a level of evidence, based on previously published criteria. Guidelines were developed based on the level of evidence, with 3 possible guideline determinations: recommendation, suggestion, or no guideline possible.

RESULTS
The literature search identified 8279 papers, 1032 of which were retrieved for detailed evaluation based on titles and abstracts. Of these, 570 qualified for final inclusion in the systematic reviews. Sixteen new guidelines were developed for or against the use of various interventions in specific treatment settings. In total, the MASCC/ISOO Mucositis Guidelines now include 32 guidelines: 22 for oral mucositis and 10 for gastrointestinal mucositis. This article describes these updated guidelines.

CONCLUSIONS
The updated MASCC/ISOO Clinical Practice Guidelines for mucositis will help clinicians provide evidence‐based management of mucositis secondary to cancer therapy. Cancer 2014;120:1453–1461. © 2014 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society.

Open Access: https://pmc.ncbi.nlm.nih.gov/articles/PMC4164022/

03/21/2025

𝐏𝐡𝐨𝐭𝐨𝐛𝐢𝐨𝐦𝐨𝐝𝐮𝐥𝐚𝐭𝐢𝐨𝐧—𝐔𝐧𝐝𝐞𝐫𝐥𝐲𝐢𝐧𝐠 𝐌𝐞𝐜𝐡𝐚𝐧𝐢𝐬𝐦 𝐚𝐧𝐝 𝐂𝐥𝐢𝐧𝐢𝐜𝐚𝐥 𝐀𝐩𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧𝐬
Dompe, et.al.

The purpose of this study is to explore the possibilities for the application of laser therapy in medicine and dentistry by analyzing lasers’ underlying mechanism of action on different cells, with a special focus on stem cells and mechanisms of repair. The interest in the application of laser therapy in medicine and dentistry has remarkably increased in the last decade. There are different types of lasers available and their usage is well defined by different parameters, such as: wavelength, energy density, power output, and duration of radiation. Laser irradiation can induce a photobiomodulatory (PBM) effect on cells and tissues, contributing to a directed modulation of cell behaviors, enhancing the processes of tissue repair. Photobiomodulation (PBM), also known as low-level laser therapy (LLLT), can induce cell proliferation and enhance stem cell differentiation. Laser therapy is a non-invasive method that contributes to pain relief and reduces inflammation, parallel to the enhanced healing and tissue repair processes. The application of these properties was employed and observed in the treatment of various diseases and conditions, such as diabetes, brain injury, spinal cord damage, dermatological conditions, oral irritation, and in different areas of dentistry.

Open Access: https://pmc.ncbi.nlm.nih.gov/articles/PMC7356229/

03/20/2025

𝐏𝐡𝐨𝐭𝐨𝐛𝐢𝐨𝐦𝐨𝐝𝐮𝐥𝐚𝐭𝐢𝐨𝐧 𝐭𝐡𝐞𝐫𝐚𝐩𝐲 𝐢𝐧 𝐧𝐨𝐧𝐚𝐥𝐜𝐨𝐡𝐨𝐥𝐢𝐜 𝐟𝐚𝐭𝐭𝐲 𝐥𝐢𝐯𝐞𝐫 𝐝𝐢𝐬𝐞𝐚𝐬𝐞
Luz Marina Gonçalves de Araujo Oliveira and Maria Cristina Chavantes

Introduction: Photobiomodulation Therapy (PBMT) can be safely employed in the treatment of liver diseases, such as Non-Alcoholic Fatty Liver Disease (NAFLD).

Materials and Methods: 32 individuals with a mean age range between 51.03 ± 9.58 years, suffering from NAFLD diagnosed by ultrasonography, were randomized into 2 study groups: Placebo's Group and PBMT's Group. Before and after the analysis period given to each group, the aforementioned individuals underwent liver ultrasonography aswell as BMI calculation and their blood samples were submitted to the following laboratory tests (plasma concentrations): Alanine Transaminase (ALT), Aspartate Transaminase (AST), Alkaline Phosphatase (ALP), Bilirubin (total and fractions) (BILI), Gamma-Glutamyl Transpeptidase or Gamma-GT (GGT), Prothrombin Time Activity (PT or PTA), Total Cholesterol and Fractions (TC - HDL, LDL) and Triglycerides (TG). Results: The PBMT’s Group demonstrated improvement in steatosis status in 93.8% of patients whereas the Placebo’s Group showed improvement in the percentage of 37.5%. Reductions in Triglycerides, Total Cholesterol, LDLand GGT levels were also observed in the PBMT’s Group.

Discussion: There was a significant enhancement in steatosis grade in the group that underwent treatment with PBMT, indicating it as a safe and effective method for treating patients with NAFLD.

Free Download:https://www.journalijdr.com/sites/default/files/issue-pdf/24275_0.pdf

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