New Edge Fitness Supplements

New Edge Fitness Supplements Health and Fitness supplements created by Milen Minev, MSc.

"My goal since I started working with people in the field of physical rehabilitation and strength and conditioning 32 years ago has been to provide them with exceptional quality and purity."

I have created my line of supplements with one goal in mind:To significantly increase your strength and fitness and actu...
03/24/2026

I have created my line of supplements with one goal in mind:

To significantly increase your strength and fitness and actually measure the change through VO2 max testing!

VO2 max test shows us how fit is the client and how strong their heart and lungs are.

NAD+ and Creatine do exactly that: increase the strength and the energy levels of your body.

I am the ONLY health and fitness professional who provides that kind of metabolic testing to his personal training clients and customers who buy his supplements!

A 2023 randomized controlled pilot study examined the effects of 5 grams/day creatine monohydrate in women diagnosed wit...
03/15/2026

A 2023 randomized controlled pilot study examined the effects of 5 grams/day creatine monohydrate in women diagnosed with maior depressive disorder and comorbid anxiety symptoms. Researchers observed a rapid reduction in anxiety severity scores within the first week of supplementation, with continued improvement across the intervention period.

Participants showed significant decreases in standardized anxiety rating scales compared to baseline, and the majority met criteria for clinical response before discontinuation. The authors proposed that creatine's role in brain energy metabolism - particularly its effects on ATP availability in the prefrontal cortex - may help regulate stress circuitry and emotional processing.

My micronized Creatine Monohydrate supplement is ultra pure, pharmaceutical grade creatine and you can purchase it in the USA by sending me a message. Creatine Monohydrate has neuroprotective properties and helps reduce the severity of dementia in elderly people.

One container is 2 months supply and the price is 25$.

The average 50 year old has 26 years left of their life.​​They’ve already completed 66% of their life.​They’ve got 9,490...
03/14/2026

The average 50 year old has 26 years left of their life.

​They’ve already completed 66% of their life.

​They’ve got 9,490 days left

and

​1,352 weekends left.

​Life is short.

​Average life expectancy for men in the US is 73,

​and for women it’s 79.

For those of you who want to fully live what's left of your time on this Earth instead of just waiting for the end as your body gets older and older, I have created New Edge Fitness training programs and supplements.

My promise to you:

I will help you add years to your Life and Strength to your years!

Why buy NAD+ and Creatine from me?Because you know me, I've been training some of you for years now and you know my obse...
03/09/2026

Why buy NAD+ and Creatine from me?
Because you know me, I've been training some of you for years now and you know my obsession with quality.
Thank you for your love and support!
Coach Milen

If you are above 50 and are tired of feeling tired, without energy, poor night sleep, brain fog, no stamina and just fee...
03/05/2026

If you are above 50 and are tired of feeling tired, without energy, poor night sleep, brain fog, no stamina and just feel that your body and mind are aging too fast, please try my NAD+
Message me if you want to support us and purchase my supplement, here I provide the third party laboratory testing of my NAD+

03/01/2026

So many people and nutritional supplements companies sell products and pills that have absolutely no positive impact and after ingestion turn into very expensive urine and excrements.

Unlike those people and companies, I have developed my NAD+ and Micronized Creatine after years of Metabolic testing and validating their effects in humans.

My NAD+ supplement provides 500 mg per serving of Nicotinamide Adenine Dinucleotide (NAD+)The body's production of NAD+ ...
03/01/2026

My NAD+ supplement provides 500 mg per serving of Nicotinamide Adenine Dinucleotide (NAD+)

The body's production of NAD+ drops by 50% by the age of fifty and unfortunately even exercise and eating right cannot restore the levels of NAD+ needed by every cell in your body. My NAD+ restores those levels and people experience that almost immediately in means of more energy and better mental clarity.

Creatine monohydrate is often cited as the most well-researched supplement in existence. As of 2026, the scientific cons...
02/24/2026

Creatine monohydrate is often cited as the most well-researched supplement in existence. As of 2026, the scientific consensus (led by organizations like the International Society of Sports Nutrition) confirms that its benefits extend far beyond just "building strong muscles."

​Here is the breakdown of the scientifically validated benefits of Creatine.

​1. Physical Performance & Muscle Growth

​The most established role of creatine is as an energy recycler. It increases your body's stores of phosphocreatine, which is used to produce ATP (the primary energy molecule) during high-intensity exercise.

​Increased Strength and Power:

Meta-analyses consistently show that individuals taking creatine experience roughly 8% more strength gains and 14% better performance in repetition tests compared to those who don't.

​Lean Mass Gains:

Creatine promotes muscle growth by:

​Increasing Cell Hydration: It draws water into muscle cells, which acts as a signal for protein synthesis.

​Reducing Protein Breakdown:

It helps preserve muscle tissue during intense training.

​Satellite Cell Signaling:

It helps with the repair and "birth" of new muscle fibers.

​Improved Recovery:

It assists in replenishing muscle glycogen (fuel) more quickly after a workout.

​2. Cognitive & Brain Health

​Research in 2025 and 2026 has significantly expanded our understanding of creatine's effect on the brain, which—like muscle—is an energy-hungry organ.

​Mental Fatigue & Sleep Deprivation:

Creatine has been shown to significantly improve cognitive performance (reasoning, memory, and reaction time) specifically when the brain is stressed, such as during sleep deprivation or intense mental work.

​Neuroprotection:

There is emerging evidence that creatine may help reduce the severity of concussions and mild traumatic brain injuries (mTBI) by maintaining brain energy levels during a crisis.

​Aging & Dementia:

Recent pilot studies (2025) indicate that higher-dose creatine supplementation may improve executive function and working memory in patients with early-stage Alzheimer's or general age-related cognitive decline.

​3. Therapeutic & General Health Benefits

​Sarcopenia Prevention:

Creatine is now highly recommended for older adults to combat age-related muscle loss and preserve bone mineral density.

​Vegetarians/Vegans:

Since creatine is primarily found in meat, those on plant-based diets often have lower baseline levels. Research shows this group typically sees the most dramatic improvements in both physical and cognitive performance when they begin supplementing.

​Blood Sugar Management:

Some studies suggest creatine can help move sugar from the blood into the muscles more efficiently, potentially improving insulin sensitivity.

My Creatine is manufactured in the USA in FDA registered laboratory and is exceptionally pure product. We do not use chloroacetic acid to manufacture cheap creatine that is so prevalent on today's market. If you are interested in my supplements, please send me a private message on Facebook messenger.

Ето научното обяснение за това как NAD+ (Никотинамид аденин динуклеотид) намалява риска от рак, представено чрез неговит...
02/23/2026

Ето научното обяснение за това как NAD+ (Никотинамид аденин динуклеотид) намалява риска от рак, представено чрез неговите основни биохимични механизми.

_________________________________________

​1. Улесняване на ДНК поправката (Механизмът PARP1)

​Най-пряката противоракова функция на NAD+ включва фамилията ензими поли(ADP-рибоза) полимерази (PARP), по-специално PARP1.

​Механизъм: Когато ДНК претърпи едноверижни прекъсвания (SSBs) вследствие на оксидативен стрес или UV радиация, PARP1 разпознава лезията и се свързва с нея.

​Зависимост от NAD+: PARP1 използва NAD+ като субстрат, за да синтезира дълги вериги от поли(ADP-рибоза) (PAR) върху себе си и околните хистони.

​Резултат: Тази „PARилация“ създава силно отрицателен заряд, който разхлабва хроматиновата структура, позволявайки на протеините за поправка (като XRCC1) достъп до увреденото място. Без достатъчно NAD+, PARP1 не може да сигнализира за поправка, което води до натрупване на мутации и потенциална злокачествена трансформация.

​2. Епигенетична регулация (Оста на Сиртуините)

​NAD+ е есенциален ко-фактор за Сиртуините (SIRT1–7) – фамилия NAD+-зависими хистонови деацетилази, които управляват генната експресия и клетъчното дълголетие.

​Геномно заглушаване: SIRT1 и SIRT6 насърчават ДНК поправката и стабилизират генома чрез деацетилиране на хистони и нехистонови протеини като p53 (известен като „страж на генома“).

​SIRT6 и теломерите: SIRT6 е критичен за поддържането на теломерите и поправката на двойноверижни прекъсвания (DSB) чрез пътя на базовата ексцизионна поправка (BER).

​Метаболитно препрограмиране:

Сиртуините предотвратяват Ефекта на Варбург (преминаването към аеробна гликолиза, характерно за рака), като регулират митохондриалната функция и потискат гликолитичните ензими.

​3. Поддържане на митохондриалното здраве

​NAD+ е централен играч в електронно-транспортната верига (ETC), където циклира между своята окислена (NAD+) и редуцирана (NADH) форма.

​Митофагия: Високите нива на NAD+ активират SIRT3 в митохондриите, което стимулира митофагията (изчистването на повредени митохондрии).

​Намаляване на ROS: Увредените митохондрии изпускат реактивни кислородни форми (ROS), които причиняват ДНК уврежданията, водещи до рак. Чрез поддържане на митохондриалния „контрол на качеството“, NAD+ значително намалява ендогенния оксидативен стрес.

​4. Директна активация на p53

​Тумор-супресорният протеин p53 е основната защита на клетката срещу рак; той задейства спиране на клетъчния цикъл или апоптоза (програмирана клетъчна смърт), когато повредите са непоправими.

​Нивата на NAD+ влияят върху активността на SIRT1, който от своя страна модулира p53 чрез деацетилиране.

​Поддържането на оптимална концентрация на NAD+ гарантира, че p53 остава чувствителен към клетъчния стрес, осигурявайки унищожаването на „счупените“ клетки, вместо да им позволи да се репликират в тумор.
#България

P.S. Ако живеете в България и искате да си закупите моя NAD+ който произхождаме в САЩ в регистрирана FDA лаборатория, моля пишете ми на лични.

Here is the scientific breakdown of how NAD+ acts as a tumor-suppressive agent:________________________________________​...
02/23/2026

Here is the scientific breakdown of how NAD+ acts as a tumor-suppressive agent:
________________________________________

​1. Facilitation of DNA Repair (The PARP1 Mechanism)

​The most direct anti-cancer function of NAD+ involves the Poly (ADP-ribose) Polymerase (PARP) family of enzymes, specifically PARP1.

​Mechanism: When DNA suffers single-strand breaks (SSBs) from oxidative stress or UV radiation, PARP1 detects the lesion and binds to it.

​NAD+ Dependency: PARP1 uses NAD+ as a substrate to synthesize long chains of poly(ADP-ribose) (PAR) on itself and surrounding histones.

​Result: This "PARylation" creates a highly negative charge that relaxes the chromatin structure, allowing repair proteins like XRCC1 to access and fix the DNA. Without sufficient NAD+, PARP1 cannot signal for repair, leading to the accumulation of mutations and potential malignant transformation.

​2. Epigenetic Regulation (The Sirtuin Axis)
​NAD+ is the essential co-factor for Sirtuins (SIRT1–7), a family of NAD+-dependent histone deacetylases that govern gene expression and cellular longevity.

​Genomic Silencing: SIRT1 and SIRT6 promote DNA repair and stabilize the genome by deacetylating histones and non-histone proteins like p53 (the "guardian of the genome").

​SIRT6 and Telomeres: SIRT6 is critical for telomere maintenance and DNA double-strand break (DSB) repair via the Base Excision Repair (BER) pathway.

​Metabolic Reprogramming: Sirtuins prevent the Warburg Effect (the shift to aerobic glycolysis common in cancer) by regulating mitochondrial function and suppressing glycolytic enzymes, thereby preventing the metabolic environment that favors tumor growth.

​3. Maintenance of Mitochondrial Health
​NAD+ is a central player in the Electron Transport Chain (ETC), where it alternates between its oxidized (NAD+) and reduced (NADH) forms.

​Mitophagy: High NAD+ levels activate SIRT3 in the mitochondria, which promotes mitophagy (the clearance of damaged mitochondria).

​ROS Reduction: Damaged mitochondria leak Reactive Oxygen Species (ROS), which cause the DNA damage that leads to cancer. By maintaining mitochondrial "quality control," NAD+ significantly lowers the endogenous oxidative stress that drives carcinogenesis.

​4. Direct p53 Activation

​The tumor suppressor protein p53 is the cell's primary defense against cancer; it triggers cell cycle arrest or apoptosis (programmed cell death) when damage is irreparable.

​NAD+ levels influence the activity of SIRT1, which in turn modulates p53 via deacetylation.

​Maintaining an optimal NAD+ concentration ensures that p53 remains responsive to cellular stress, ensuring that "broken" cells are destroyed rather than allowed to replicate into a tumor.


P.S. If you are interested in my NAD+ supplement which we manufacture in the USA in FDA registered laboratory, please send me a private message.

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