
09/26/2025
The UK is taking a vigorous approach to engaging individuals and their families after screenings reveal the presence of T1D autoantibodies, which signals the risk of progression to clinical .
TEDDY and Fr1da studies are cited:
"As may be expected, there is an increase in psychological distress (anxiety, depression) when parents (particularly maternal caregivers) are given the news that their child is IAb positive; although in the Fr1da study, psychological distress (depression) seen in parents of IAb positive children returned to baseline within 6–12 months.9 However, in the TEDDY study, anxiety levels in parents of children identified as genetically at-risk only reduced if they were informed that their child was IAb negative. Dropout rates after the first IAb screen can be as high as 50%. The benefits of screening programmes (DKA reduction) are only seen in the context of active monitoring, rather than screening alone. A monitoring programme that is practical and encourages engagement is crucial. It is unclear what the long-term effect is of living with the knowledge of risk, for example, the impact on lifestyle, behaviour and mood; and research is underway to address these knowledge gaps."
Diabetic Medicine | Diabetes UK Journal | Wiley Online Library https://onlinelibrary.wiley.com/doi/10.1111/dme.70117
Health care providers interested in learning more about T1D screenings, diagnoses, and monitoring should review STOP T1D's free online course. Visit stopt1dprogram.org/for-hcp to learn more and register.
Screening for childhood type 1 diabetes (T1D) is increasing worldwide. Historically, screening has been undertaken through research programmes, but increasingly in the UK, children and young people a...