01/08/2026
A 2024 human study published in the Journal of Biophotonics by Michael B. Powner and Glen Jeffery investigated whether red-light photobiomodulation affects blood glucose regulation. Healthy adult participants underwent a standard oral glucose tolerance test, with and without exposure to 670 nm red light for 15 minutes. Blood glucose was measured over a 2-hour period following glucose intake to assess post-challenge glucose dynamics.
The study found that a single 15-minute exposure to 670 nm red light reduced total post-glucose blood sugar elevation by 27.7% over two hours, measured as area under the curve, and lowered peak glucose levels by approximately 7.5% compared to control conditions. The proposed mechanism is enhanced mitochondrial activity: red light increases mitochondrial membrane potential and ATP production, raising cellular glucose demand and thereby reducing circulating blood glucose. These results suggest red-light photobiomodulation can acutely blunt post-meal glucose spikes in healthy adults, though longer-term and clinical population studies are still needed.
PMID: 38378043