Amylyx Pharmaceuticals Inc.

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Amylyx Pharmaceuticals Inc.

Ushering in a new era for treating diseases with high unmet needs

03/09/2026

This week, is at Muscular Dystrophy Association's Clinical and Scientific Conference, where we’re presenting an update on our Phase 1 LUMINA trial in . More details below.

02/27/2026

Ahead of tomorrow, Amylyx honors the resilience of those living with rare diseases and the communities that stand beside them. At our recent Anchor Week, we gathered for a Rare Night Out to recognize our shared purpose and participated in Rare Disease Trivia to promote awareness and connection.

02/24/2026

Happy Amylyx Anniversary to Jim Frates, Dan Sitte, Jenny Tavares, and Eric Cooksey! At this month’s Anchor Week, we celebrated the many contributions they’ve made the past 5 years and thanked them for their unwavering commitment to developing novel therapies for communities with high unmet needs.

02/19/2026

We were honored to host Cindy and her husband Ray at our recent Anchor Week. They shared with us the partnership, determination, and hope that have been critical throughout Cindy's journey with post-bariatric hypoglycemia (PBH).

The communities we collaborate with drive us forward, and Cindy and Ray brought our work to life in such a powerful way. Thank you for speaking with !

02/17/2026

Post-bariatric hypoglycemia (PBH) is thought to be caused by changes in hormonal and glycemic patterns, including an excessive glucagon-like peptide-1 (GLP-1) response, leading to repeated episodes of low blood sugar (also know as hypoglycemia) that impair quality of life.

Over time, repeated episodes of hypoglycemia can lead to hypoglycemia unawareness, a condition where the body does not produce the typical early warning signs of hypoglycemia until blood sugar levels drop dangerously low. Learn more about PBH on our website at https://bit.ly/4tCBxTD

02/12/2026

What does it mean to be Rooted in Connection?

Amylyx values the connections between our company and the communities we serve, between questions and solutions, and between insights and actions. We see a path between where we are and where we need to be. Our work, our motivation, and the core values that guide us are deeply interwoven.

Learn more about our company: https://bit.ly/4qsj2OF

02/11/2026

Last week, gathered at headquarters for Anchor Week, a special time for collaboration and connection across our hybrid-remote team and with guests from the broader community. Check out some of the highlights below.

02/06/2026

Raquel’s path to a diagnosis of started at 4 years old when she was diagnosed with diabetes. She started losing her vision at 5 years old. In honor of upcoming , hear her story on this rare condition that affects approximately 3,000 people in the U.S. at https://bit.ly/3Zmju65

02/03/2026

ALS is a relentlessly progressive and fatal neurodegenerative disorder caused by motor neuron death in the brain and spinal cord.

Calpain-2, when overactive, may play an important role in how ALS and other neurodegenerative diseases progress. In research studies, blocking calpain-2 activity has been shown to help protect nerve fibers and support neuron health. Learn more about the connection between calpain-2 and ALS on our website at https://bit.ly/3OhjKkm.

01/30/2026

Wolfram syndrome is a rare genetic disorder that affects approximately 3,000 people living in the U.S. with no approved treatment options.

Common manifestations of Wolfram syndrome include insulin-requiring diabetes mellitus, vision loss, diabetes insipidus, hearing loss, neurogenic bladder, impaired balance and coordination, and difficulty breathing that can progress to respiratory failure. Learn more about Wolfram syndrome on our website at: https://bit.ly/3Zbrhnf

01/26/2026

Our team is growing! Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. If you share our passion and are determined to tackle some of medicine’s toughest challenges, check out the opportunities here and apply: https://www.amylyx.com/open-positions

01/23/2026

Community voices drive innovation. To change the trajectory of diseases with high unmet needs, we first listen to those impacted.

Jessica is a passionate mother, case manager, and advocate with post-bariatric (PBH). She shared her story – and unwavering determination – with us to raise : https://amylyx.com/jessicas-PBH-story

If you’re interested in sharing your experience with PBH, email pbhcommunity@amylyx.com.

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55 Cambridge Parkway, Suite 6W
Cambridge, MA
02142

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