
02/15/2025
HER2- breast cancer patients are often curious about how much benefit they may receive from hormone-blocking therapies and often ask do the benefit outweigh the risks and adverse effects? New research has found that in the future the percentage of ER receptors may be used to guide treatment options https://www.nature.com/articles/s41598-025-90134-9?fbclid=IwZXh0bgNhZW0CMTEAAR01I8Njyof1LXgBq3bl8WyvMFBxG4c6q5uaAWZmFcGlVlmFu2zng2ceGZM_aem_PIhCKZCkofwjWcWN82cdHAnt options.
We used a novel shape-restricted Cox model to determine the desirable ER expression cutoff to predict breast cancer prognoses. Our model treats ER as a continuous variable using a flexible monotone-shaped Cox regression to assess its association with survival outcomes holistically. The study include...