05/15/2026
PCOS is no longer called that, and it has been renamed! 🙌🏽
Polycystic O***y Syndrome has been renamed to PMOS — Polyendocrine Metabolic Ovarian Syndrome.
PCOS NEVER 🙅🏽 really made sense.
First of all, the syndrome has never actually been based on ovarian cysts. These patients do NOT have cysts — they have many antral follicles, meaning a very high ovarian reserve. These are NOT cysts; they do not cause pain, nor do they increase cancer or surgical risk. They are simply lots of eggs!
Second, the old name did not truly describe the syndrome, but now it does!
POLYENDOCRINE
— Involves abnormalities in neuroendocrine hormones such as LH and FSH, insulin, and androgens like testosterone. So it also describes the high diabetes risk with related issues like increased facial hair, acne, and male-pattern hair loss.
METABOLIC — Correctly describes the association with obesity, insulin resistance, fatty liver disease, high cholesterol, and cardiovascular risks that these women carry long after their reproductive years.
OVARIAN — Infrequent ovulation, many antral follicles seen on ultrasound, high ovarian reserve, infertility.
SYNDROME — Meaning it includes many medical aspects and not just a single cause: genetics, environment, etc.
Other related factors include abnormalities in the endometrium such as precancerous changes, depression, anxiety, and sleep apnea, among others.
But this new name correctly describes most of the associated symptoms, which we hope will help properly diagnose and treat the 70% of people who have MPOS but have never been diagnosed! Diagnosis is essential to prevent the serious associated complications, since it is the most common endocrine disorder in women of reproductive age, affecting more than 10% of women!!!
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