God Grant Us The Serenity"

10/24/2025

10/19/2025

Traumatic Brain Injury is a global health challenge that substantially contributes to disability and is responsible for 30% of injury-related deaths.

Annually, over 50 million TBIs occur , & accounts for approximately 30% of injury-related deaths. TBI often results in cognitive impairment, depression, and an increased risk of developing neuropsychiatric diseases, including Parkinson’s and Alzheimer’s diseases, and substance abuse disorders. Notably, alcohol consumption significantly raises TBI risk, with many patients intoxicated during injury. This interplay between alcohol and TBI complicates recovery, as alcohol use can impede neurological healing, and TBI may increase alcohol and substance use.

A recent study, researchers demonstrated that the fluid percussion injury (FPI) model of TBI in male C57BL/6 mice significantly increases alcohol consumption and impairs cognitive function. FPI markedly reduced the number and activity of striatal cholinergic interneurons (CINs) while increasing striatal microglial cells. Then, tested the hypothesis that FPI in mice increases alcohol intake, impairs striatal CIN function, and causes cognitive impairment. Additionally, researchers investigated whether microglial ablation could improve striatal cholinergic function. The results show that FPI increased alcohol preference and induced a hypo-cholinergic state in the striatum. Crucially, microglial depletion using PLX 5622 enhanced cholinergic activity, indicating that microglia could contribute to striatal cholinergic dysfunction following FPI.

Overall, this study identifies the striatal cholinergic system as a potential therapeutic target to mitigate the neurological effects of TBI, including increased alcohol abuse and cognitive deficits.

One love

08/02/2025

https://www.facebook.com/share/17AgtVnk6Q/?mibextid=wwXIfr

A fundraising platform of International 🌍❤️ Fight child poverty. One cause at a time. Give directly to children and communities in need and receive progress updates! First $50K in donations matched so every dollar goes further.

08/02/2025

A baby with a cleft is born every 3 minutes. These babies can experience isolation and often face prejudice in their communities. No child deserves to feel like an outcast.You can save a child’s life with the gift of cleft treatment.

07/31/2025

https://youtu.be/lE7f07KFnLg?si=uD7GSxHeltHJLDXm

07/31/2025

A great organization that saves ao many dogs a year. I’’m thinking of all that make life better sor so many doggies.
aar

By Soul Dog Rescue

06/04/2025

Hello everyone out there who is God grant the serenity Page member. I currently I’m trying to raise money for a cause to help provide services and help spread awareness about traumatic brain injury, which affects more and more people every year, some silently, and all that are affected have a need services. Anyway, here is my link to my fundraising site through TBI America.
Thank you ahead pf time if you’re helping irs a super cause. And if you know of people in your realm of life, know that if they’re suffering from head injury, they’re suffering from a lot more than can be told .

I’m raising money for cause that for those who have been lucky enough to have never had anyone in their family or friends network that has sustained any type of significant Brain Injury, I can tell you firsthand that it is devastating and one of the hardest trials one will ever base in life, and t...

04/26/2025

I can't.

04/22/2025

04/22/2025

St. Jude Walk

04/20/2025

Hey everybody trying to walk this month for a good cause. Post more later