04/12/2025
I was floored recently by a post I saw on X, exhorting readers to not be organ donors. The implication was that if you check the organ donor consent on your driver's license, that you may have your organs taken before you are dead.
This is something I have experience interacting with, from my nursing days, from residency, and from my current career, and I would like to clarify the issue for my readers and explain the process.
There are several types of organ and tissue donation:
1. Living donor
2. Donation after brain death
3. Donation after cardiac death
4. Post-death tissue donation
Living donor would be a donation of one kidney, part of a liver, bone marrow, plasma, or blood. These donations do not significantly impact the longevity of the donor in most cases (barring unforeseen surgical complications). They are, aside from plasma donation, strictly due to a generous person being willing to help another human.
Donation after brain death is the most common organ transplantation, in my understanding. To explain the process, I must first explain brain death.
Brain tissue lives inside a closed box, which we think of as our skull. It does not expand, and when the brain swells after an injury in the same way we swell in other areas after injury, there's no place for the swollen organ to expand to. Pressure inside the skull (cranium) rises, and eventually blood cannot flow in to feed the brain. Brain tissue uses a lot of energy to work, and when fuel (glucose) and oxygen stop flowing to the brain, it starts to die in 6 minutes or less. Once dead, it's not coming back.
So, after a head injury or major stroke, this can happen. The autonomous parts of the body, including heart and blood vessels, continue to function, albeit without the normal controls from the brain, as long as we keep air moving in and out of the lungs and fluid and electrolytes balanced in the blood, for a period of time, generally a few days.
The donation process in this situation is that the donor services are notified of a likely impending death, and they send a representative who reviews the status of the patient and the likelihood that there may be viable organs. This person has no influence on care, does not talk with the family, begins coordinating for potential organ matches, and remains on standby until the team caring for the brain-injured patient has exhausted all options for survival and has determined that the patient is brain dead. This is usually confirmed by a blood flow study that proves no blood flow to the brain.
Only after brain death is declared do the transplant coordinators make contact with family, explain the process, and receive consent for donation. While your registration is legally all that is required for consent, family consent is usually attempted and honored. In the event that family is not available, donation can proceed based on the patient's opt-in status.
Once the donation process begins, the transplant coordinator assumes the role of advising care along with the primary medical team. This includes ordering various drugs and labs and managing fluid and electrolyte replacement. This process continues up to the point of the surgical removal of viable organs.
In the operating room, the anesthesia team provides surgical anesthesia just like any other surgery. Even though there is no brain function, the spinal cord still has functioning reflex circuits, so anesthesia limits these responses. The anesthesia team remains active until the heart and lungs have been removed.
Donation after Cardiac Death (DCD) is a more recently accepted procedure where a patient in a persistent vegetative state has care withdrawn and then organs are removed after cardiac death has been confirmed. This is less common, and organ viability is lower than donation after brain death or living donor donation. Again, safeguards are in place so that donation does not influence the decision to withdraw care. I do not have any interface with this process, so I can't comment beyond what I've read.
Post-death tissue donation includes donation of cornea tissue, and bone and tendon donation. These are low-metabolic-activity tissues that do not have as tight a time window for donation.
As physicians, nurses, and support personnel, we take the ethical concerns surrounding the donation process seriously, and we honor the safeguards that are set up to prevent perverse incentives from influencing our care of the living patient.
The online criticism I'm seeing regarding organ donation suggests otherwise, and there are those seeking to spread fear and mistrust regarding organ donation.
Some imply that the financial incentives of donation lead to patients being declared brain dead when they are not, or that care is withdrawn for the purpose of donation. I acknowledge that it could in theory be possible, and I've heard many rumors of this being done in China to political prisoners. But here, in the United States, this would not be tolerated, and I expect that anyone who might do this would be reported by other care team members quite readily.
COVID deepened the mistrust of the health-care industry, and this mistrust feeds into the traction that that these online purveyors of the anti-organ-donation narrative are getting. While I understand that feeling, I believe strongly that it is misplaced, and that the organ donation process in the United States is as ethical as it can be made to be. Many people simply do not understand the process, or actively seek to get attention by telling falsehoods about it.
Organ donation saves lives.
I am a registered organ donor, and have no concerns about that process being abused.
(And yes, the professionals who are part of the process of organ donation do get paid our regular salary, but did you expect us to work for free? It isn't like any of us get a bonus because we recruited a donation. Instead, we get a nice letter from the donor services, telling a little bit about who received the organs.)