
10/01/2025
Let's do Phytochemistry Friday on a Monday this week.
Formulating herbal remedies is a matter of being strategic with the intersections of biology, chemistry (and etc) and a little bit of energetics.
Take one of the most common and easily obtainable plants used as a medicinal herb in the US.... calendula officinalis... the common marigold. You have it sitting in posts most of the summer.
Not all parts of the calendula flower contain the same compounds โ and this matters when we talk about its therapeutic applications.
๐ Petals (ray florets):
Carotenoids (lutein, zeaxanthin, ฮฒ-carotene) โ major contributors to antioxidant capacity + pigment activity
Flavonoids (quercetin, isorhamnetin, rutin) โ vascular support, free-radical scavenging
Lower concentrations of resins compared to the central florets
๐ Disc florets (inner portion):
Triterpenoid saponins + resins (oleanolic acid derivatives, sterols) โ primary agents in wound-healing and antimicrobial effects
Volatile oils (sesquiterpenes, ฮฑ-cadinol, ฮณ-cadinene) โ antiseptic, anti-inflammatory
Polysaccharides โ immunomodulatory potential
Why use the whole flower?
Petals provide pigment-rich antioxidants and capillary support
Inner florets deliver pharmacologically active resins, saponins, and oils
Together โ a synergistic profile that supports tissue repair, antimicrobial defense, and immune modulation
Calendula can be chemically strategic.
yet another reason I carefully choose my ingredient sources and when possible, I buy whole plants and prepare them myself, rather than buying pre-ground.