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This page is dedicated to sharing peer-reviewed medical articles pertaining to Ehlers-Danlos Syndrome. Share freely for EDS science awareness! 🦓

This is the sister page for the group “Ehlers-Danlos Syndrome Medical Articles”.

01/02/2026

2025 Sources and consequences of self-doubt in patients with Ehlers-Danlos syndrome: a qualitative study in Europe and North America

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12/31/2025

2025 Challenges in the Management of Patients with Vascular Ehlers-Danlos Syndrome: Lessons from three Clinical Cases

Challenges in the management of patients with vascular Ehlers-Danlos syndrome: lessons from three clinical cases Lara Alayasa Al-Quds University, Faculty of Medicine, Abu Dis, Palestine Razan Fiala Al-Quds University, Faculty of Medicine, Abu Dis, Palestine Adriana Skafi Al-Quds University, Faculty....

12/31/2025

2025 Clinical Presentation, Diagnostic Delays, and Treatment Outcomes in Postural Orthostatic Tachycardia Syndrome (POTS): An Observational Case Series Study in a Single-Centre District General Hospital

Background: Postural orthostatic tachycardia syndrome (POTS) is a heterogeneous disorder of autonomic regulation characterised by unexplained orthostatic tachycardia in the absence of postural hypotension. POTS is a complex and challenging diagnosis owing to the non-specific nature of the present.....

12/31/2025

2025 Surgical management of progressive spinal deformities in FKBP14-associated Ehlers-Danlos syndrome: a case report and literature review

This report aims to present a comprehensive case of progressive spinal instability in kyphoscoliotic Ehlers-Danlos syndrome (EDS) and review the surgical management literature to provide insights into treatment strategies for this challenging ...

12/31/2025

2025 Comprehensive Risk Profile of Gastrointestinal and Extra Articular Comorbidities in Ehlers-Danlos Syndrome: A Propensity-Matched Analysis of 118,256 Individuals

Using a large-scale database and propensity score matching, this study demonstrates that Ehlers–Danlos Syndrome patients have significantly elevated risks for gastrointestinal comorbidities (GERD, IB...

12/31/2025

2025 Perceived quality of life, fatigue and the metabolic cost of walking in generalized hypermobility spectrum disorder and hypermobile Ehlers-Danlos syndrome

IntroductionIndividuals with hypermobile Ehlers-Danlos Syndrome (hEDS) and Hypermobility Spectrum Disorders (HSD) often experience chronic pain, leg fatigue ...

12/31/2025

2025 Distressing Bleeding Symptoms in Interviews of Patients With Hypermobile Ehlers–Danlos Syndrome and Hypermobility Spectrum Disorder

Introduction Hypermobile Ehlers–Danlos Syndrome (hEDS) and hypermobility spectrum disorder (HSD) are associated with symptoms in many organ, but those related to haemostasis are not fully characteri...

12/30/2025

2025 Diaphragmatic Hernia in a Newborn With COL1A1-Associated Classical Ehlers–Danlos Syndrome

Diaphragmatic rupture is an uncommonly seen complication of classical Ehlers–Danlos syndrome (cEDS). There have been no documented cases of diaphragmatic hernia in newborns having cEDS. This case stu...

12/30/2025

2025 Chest Imaging Findings and Tissue Biopsy Experience in a Patient with Type IV Ehlers-Danlos Syndrome: A Case Report

Vascular Ehlers-Danlos syndrome (EDS) is a rare genetic connective tissue disorder caused by abnormalities in extracellular matrix components, such as collagen. Among the six subtypes of EDS, type IV is known to have the worst prognosis. However, ...

12/30/2025

2025 A Caregiver's Perspective: Identifying “Zebras”—Listening to Patients is a Clinical Necessity

This caregiver perspective article shares a decades-long experience of a family navigating the health system to obtain an accurate diagnosis for their nonbinary...

12/09/2025

2025 Aortic Tissue Proteome Alterations in Vascular Ehlers-Danlos Syndrome

Vascular Ehlers-Danlos syndrome (vEDS) is a rare connective tissue disorder caused by mutations in the COL3A1 gene, leading to life-threatening vascular complications. This study presents a proteomic analysis of aortic wall tissue from a 60 year-old vEDS patient with a confirmed COL3A1...

12/08/2025

2025 Clinical utility of chromosomal microarray and whole exome sequencing in evaluating genetic causes for pregnancy loss using products of conception specimens

Objectives To determine the genetic causes of miscarriage by analyzing products of conception (POC). Methods Chromosomal microarray (CMA) using the Affymetrix Cytoscan HD array was performed in 172 POC specimens from women experiencing spontaneous miscarriage before 20 weeks of gestation to detect a...

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