Beat Alzheimer's Disease

02/13/2024

Large-scale proteomics data hold promise for individual disease risk prediction. Here the authors use data from more than 50,000 adults without dementia in the UK Biobank to predict the future risk of dementia and highlight GFAP as an important protein elevated in individuals more likely to develop....

01/31/2024

https://www.nytimes.com/2024/01/16/well/mind/dementia-bilingual-language.html

Research suggests that bilingual people enjoy some cognitive benefits later in life, but it probably requires more than a few Spanish lessons in your 60s.

12/10/2023

https://www.economist.com/the-economist-reads/2023/12/03/what-to-read-about-dementia

How the disease will change the world and what the prospects are for treating it

12/06/2023

https://www.wsj.com/health/healthcare/medical-studies-too-white-14e60b22?mod=hp_lead_pos11

Efforts to diversify clinical trials seek to ensure devices, drugs and prevention work for all.

12/06/2023

https://www.nytimes.com/2023/11/15/health/million-veterans-database-va.html

Diverse data from the Million Veteran Program has already contributed to hundreds of medical studies, and the V.A. is continuing to recruit more participants.

11/15/2023

Machine-learning approach detects Alzheimer’s disease with an accuracy of more than 90% — a potential boon for clinicians and scientists developing treatments.

11/09/2023

https://www.nytimes.com/2023/11/08/well/mind/mental-illness-depression-dementia.html

Research is revealing an inextricable link between mental disorders and neurological disorders.

11/06/2023

Research shows that a daily dose of tai chi, the slow-moving meditative, martial art can boost our body and brain. A new study finds adding word games to tai chi doubles the increase in memory.

10/03/2023

People with an abundance of specific neurons are more likely to escape cognitive decline despite having signs of Alzheimer’s in their brains.

10/01/2023

This Review summarizes recent advances in biomarkers and therapies for Alzheimer disease—the products of decades of research—and discusses the challenges, gaps and clinical implications.

08/03/2023

Under-representation of people of colour sparks concerns over the safety and efficacy of drugs in diverse populations.

07/26/2023

Abnormal levels of certain proteins — many of which have roles outside the brain — could be an early hallmark of Alzheimer’s disease or similar conditions.

07/19/2023

A trial of donanemab, an experimental drug, found it modestly slowed the worsening of memory and thinking and worked better in patients at earlier stages and those under 75.

07/14/2023

A leading researcher on Alzheimer’s discusses the latest tools for detecting the disease, health steps you can take and what advances he sees for the next 10 years.

07/07/2023

The F.D.A. gave full approval to the drug, but added a black-box warning about safety risks. Medicare said it would cover most of the high cost.

06/28/2023

Gainesville, wanted to combine those older data with his own to perform a long-term analysis. It was easier said than done. Whereas Acevedo’s data were logged using a standardized data-entry template, the colleague’s data were recorded in a mix of paper notebooks, Excel spreadsheets and hand-drawn maps. “It was some of the most organized data of that era, but we didn’t have the standards then that we have today,” he says. Columns weren’t necessarily consistent from sheet to sheet, nor did they use the same units, and it wasn’t always clear which sampling sites were being measured.

Specialists offer seven tips for effectively sharing your data.

06/25/2023

Alzheimer’s disease, which is the most common form of dementia, affects 6.7 million adults over 65 years old in the United States. It not only slowly destroys a person’s memory but also diminishes communication skills, eroding the ability to understand the meanings of words or to find the right ones.

The family of the celebrity zookeeper Jack Hanna is speaking publicly about the difficulties communicating with him now that he has Alzheimer’s. Experts say that such interactions take patience and sensitivity.

05/16/2023

Genetic resilience found in a person predisposed to early-onset dementia could potentially lead to new treatments.

05/06/2023

Donanemab is not a cure and comes with significant side effects, but patients had longer periods of independent living while on the drug.

05/06/2023

Eating packaged foods like cereal and frozen meals has been associated with anxiety, depression and cognitive decline. Scientists are still piecing together why.

04/29/2023

https://www.nytimes.com/2023/04/28/health/bilingualism-memory-dementia.html?action=click&module=Well&pgtype=Homepage§ion=Health

People who spoke two languages daily in their youth tended to score higher on memory tests later in life, the researchers found.

04/10/2023

Researchers are looking to drug combinations, vaccines and gene therapy as they forge the next generation of treatments for the condition.

04/01/2023

https://www.nytimes.com/2022/03/01/books/review/in-love-amy-bloom.html

Amy Bloom’s midlife love story was interrupted by a dreaded diagnosis. In her memoir, “In Love,” she writes about what happened next.

02/17/2023

Researchers found associations between certain viral illnesses and the risk of Alzheimer’s and other neurodegenerative diseases.

01/11/2023

Reports of deaths potentially linked to the treatment have cast a shadow on what many hail as a landmark approval.

01/07/2023

It has become the bedrock of virtuous eating. Experts answer common questions about how it leads to better health.

01/06/2023

The drug, Leqembi, may modestly slow cognitive decline in early stages of the disease but carries some safety risks. Still, data suggests it is more promising than the small number of other available treatments.

11/19/2022

One of the strongest risk factors for dementia is the ε4 variant of the APOE gene. Yet, many who carry it never develop dementia. The current study examined for the first time whether positive age beliefs that are acquired from the culture may reduce the risk of developing dementia among older indi...