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Vital Pulse Healthy Heart, Happy Life

02/27/2024

Too much cholesterol in our blood is unanimously recognized to be a risk factor for the development of Alzheimer’s disease. Those with a total cholesterol of 225 (mg/dL) or more may have nearly 25 times the odds of ending up with amyloid plaques in their brain 10 to 15 years later.

LDL cholesterol levels average 40 points higher in those with bad gene variants of APOE, but after switching to a diet lower in animal fat, that cholesterol difference can effectively be smoothed out. So, diet can trump genetics.

This may explain the so-called Nigerian paradox: They have among the highest rates of the Alzheimer’s gene, but some of the lowest rates of Alzheimer’s disease. The paradox may be explained by their low cholesterol levels, probably because of their diets low in animal fat.
In terms of dietary guidelines for the prevention of Alzheimer’s, we should center our diets around whole, plant-based foods, such as whole grains, legumes, fruits, and vegetables.
To drastically lower LDL cholesterol levels, we need to drastically reduce our intake of trans fat (found in processed foods and naturally in meat and dairy), saturated fat (found mainly in animal products and junk foods), and dietary cholesterol (found exclusively in animal products, especially eggs).

Watch the video “How Not to Age – Live Presentation” at https://see.nf/45P50wv to learn more.

How Not to Age is out now! Borrow a copy from your local library or order one today: https://see.nf/HNTABook

02/27/2024

If you take young, healthy people and split them into two groups, half on a fat-rich diet and the other half on a carb-rich diet, within just two days, glucose intolerance skyrockets in the fatty diet group. In response to the same sugar water challenge, those who had been taking in a lot of fat ended up with twice the blood sugar. As the amount of fat in the diet goes up, our blood sugar spikes.

Insulin is the key that unlocks the door to our cells to let blood sugar enter and be used or stored as energy. If there was no insulin, blood sugar would be stuck out in the bloodstream, banging on the doors to our cells but unable to get inside. So, with nowhere to go, sugar levels would rise and rise. That’s what happens in type 1 diabetes: The cells in the pancreas that make insulin get destroyed, and, without insulin, sugar in the blood can’t get out of the blood and into our cells, and, therefore, blood sugar rises.

What if there’s enough insulin being produced, but the insulin doesn’t work (as in cases of type 2 diabetes)? When insulin is present, but something is gumming up the lock to open the cell wall, not allowing it to work properly, that’s called insulin resistance. Our cells become resistant to the effect of insulin.

What’s causing this? Fat in the bloodstream can build up inside our muscle cells and create toxic, fatty, breakdown products and free radicals that can block the signaling pathway process. So, no matter how much insulin we have in our blood, it isn’t able to open the glucose gates, and blood sugar levels build up.

This mechanism, by which fat (specifically saturated fat) induces insulin resistance, wasn’t known until fancy MRI techniques were developed to see what was happening inside people’s muscles as fat was infused into their bloodstream.

Insulin doesn’t work as well on a high-fat diet, like a ketogenic one. Our bodies are insulin-resistant. As the amount of fat in our diet gets lower and lower, insulin works better and better. Watch the video "What Causes Insulin Resistance?" on NutritionFacts.org to learn more: http://bit.ly/2t58PeF.

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