06/20/2024
Vitamin B12 plays a crucial role in various metabolic pathways in the human body. It is essential for the normal function of the blood, eyes, neural system, and DNA synthesis, among other functions. For instance, vitamin B12 is necessary for the synthesis and function of hemoglobin, the oxygen-carrying molecule in red blood cells. Hemoglobin's main component, iron, binds oxygen in the lungs and releases it in the tissues. Vitamin B12 is vital for iron absorption; a deficiency in vitamin B12 can lead to pernicious anemia (also known as vitamin B12/folate deficiency anemia). This condition often results from the body's inability to absorb B12 in the stomach. In such cases, doctors may prescribe injectable vitamin B12.
Injectable vitamin B12 is available in three forms: cyanocobalamin, methylcobalamin, and hydroxocobalamin. The difference between them lies in their biochemistry and usage. When cyanocobalamin is processed by the body, it converts into methylcobalamin, the naturally occurring active form of B12. Cyanocobalamin is equivalent to methylcobalamin as a dietary supplement, but methylcobalamin is preferred for individuals with peripheral neuropathy, whether related to diabetes or not. Hydroxocobalamin is often prescribed by ophthalmologists and is used for other medical purposes. However, hydroxocobalamin is currently on the FDA drug shortage list.
Both injectable methylcobalamin and hydroxocobalamin can be compounded and are available at the Palm Beach Compounding Pharmacy by prescription.
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